摘要
广泛性焦虑障碍(Generalized Anxiety Disorder,GAD)是一种以焦虑为主要临床症状的常见精神疾病,其患病率逐年增高,并有慢性致残的风险,严重影响着人类的身体和心理健康。文章主要从病因病机、辨证分型和治疗方法方面梳理了GAD的中医药研究进展,结果表明GAD的发生可能是刺激源如不良社会生活事件,作用于易感体质的个体,引起心肝等内在脏腑功能失常,进一步产生痰、饮、水、湿、瘀、火等病理因素为主要病因病机,辨证分型主要有心肾不交型、肝郁化火型、痰火上扰型、心脾两虚型、心胆气虚和阴虚内热型。治疗主要有辨证论治、针灸推拿等,其临床疗效显著且远期疗效优于西药治疗,但亦存在缺乏客观证候诊断及疗效评价标准,缺少对发病机制和中药治疗GAD作用靶点的系统深入科学研究等问题,以期为GAD今后的诊疗优化和发病机制的深入研究提供参考。
Generalized Anxiety Disorder(GAD)is a common mental illness with anxiety as its main clinical symptom.Its prevalence is increasing year by year,and it has the risk of chronic disability,which seriously affects human physical and mental health.This article mainly from the etiology and pathogenesis,syndrome differentiation and treatment method has combed the GAD's research progress of traditional Chinese medicine(TCM),the results show that the occurrence of GAD may be a stimulus such as poor social life events,applies to susceptible individuals,heart and other internal viscera function disorder,further produce sputum,drinks,water,dampness,blood stasis,fire as the main etiology and pathogenesis,pathological factors.The syndrome differentiation types are mainly heart and kidney noncommunication type,liver stagnation and fire type,phlegm and fire on the disturbance type,heart and spleen deficiency type,heart and gallbladder qi deficiency and Yin deficiency internal heat type.Treatment mainly include syndrome differentiation and treatment,acupuncture and massage,etc.,the clinical curative effect is distinct,and the forward curative effect is superior to western medicine treatment,but there is also a lack of objective and syndromes curative effect evaluation standard,lack of the mechanism and system of TCM in the treatment of GAD targets into issues of scientific research,in order to optimization and the pathogenesis of GAD for the future of the diagnosis and treatment to provide reference for further studies.
作者
张衍卿
于艳红
王德润
Zhang Yanqing;Yu Yanhong;Wang Derun(College of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2023年第7期2248-2255,共8页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金委员会面上项目(81573829):抑郁症肝气郁证患者抑郁眼神、面部表情和姿态多模态识别及其脑区功能定位,负责人:于艳红。
关键词
广泛性焦虑障碍
中医药
辨证论治
研究进展
Generalized anxiety disorder
Traditional Chinese medicine
Treatment based on syndrome differentiation
Research progress
