摘要
目的分析徐州市肾综合征出血热的流行特点及临床表现,为临床诊断及预防控制提供科学依据。方法收集徐州市2010—2021年累计报告的347例肾综合征出血热个案调查资料,应用SPSS 19.0对相关数据进行统计分析。结果2010—2021年徐州市累计报告肾综合征出血热347例,患者平均年龄为(47.27±13.76)岁,其中男性280例,女性67例,男女性别比为4.18∶1;累计报告死亡病例2例。2010—2021年发病率波动在0.17/10万~0.55/10万,年平均发病率为0.33/10万。发病高峰为10—12月(224例,占64.55%),年龄以35~65岁组为主(240例),占69.16%,职业分布以农民为主(269例),占77.52%;累计报告病例数居前3位的依次为新沂市90例(25.94%)、邳州市79例(22.77%)、铜山区51例(14.70%),累计报告发病率较高的3个县区依次为新沂市(0.80/10万)、邳州市(0.45/10万)和贾汪区(0.41/10万)。症状以轻型和中型为主(83.29%),临床表现以急性起病为主(94.24%),多见发热(92.51%)、乏力(91.35%)、血小板减少(74.64%)、白细胞计数增多(71.47%)等症状。58.50%的患者7 d内确诊,97.12%的患者从未接种过疫苗,93.66%的患者有明确的接触史。结论2010—2021年徐州市肾综合征出血热发病呈现出高度散发状态,以轻型和中型为主,维持在较低的发病水平,大部分病例的预后良好,应继续做好全市肾综合征出血热疫情监测、防鼠灭鼠及开展重点人群的健康教育工作。
Objective To analyze the epidemiological characteristics and clinical manifestations of hemorrhagic fever with renal syndrome(HFRS)in Xuzhou City,so as to provide scientific evidence for clinical diagnosis,prevention,and control.Methods The survey data of 347 cases of HFRS reported in Xuzhou City from 2010 to 2021 were collected,and SPSS19.0 was used to statistically analyze the relevant data.Results From 2010 to 2021,a total of 347 cases of HFRS were reported in Xuzhou City,with an average age of(47.27±13.76)years,including 280 males and 67 females,with a male⁃to⁃female sex ratio of 4.18∶1,and 2 deaths were reported.From 2010 to 2021,the incidence fluctuated from 0.17/105 to 0.55/105,and the average annual incidence rate was 0.33/105.The peak incidence was from October to December(224 cases,account⁃ing for 64.55%),the age group was mainly 35-65 years old(240 cases),accounting for 69.16%,and the occupational distribu⁃tion was mainly farmers(269 cases),accounting for 77.52%.The top three cumulative reported cases were 90 cases(25.94%)in Xinyi City,79 cases(22.77%)in Pizhou City,and 51 cases(14.70%)in Tongshan District and the three counties(districts)with higher cumulative reported incidence rates were Xinyi City(0.80/105),Pizhou City(0.45/105)and Jia Wang District(0.41/105).The symptoms were mainly mild and medium(83.29%),and the clinical manifestations were mainly acute onset(94.24%).Fever(92.51%),fatigue(91.35%),thrombocytopenia(74.64%),and increased white blood cell count(71.47%)were more common.Totally 58.50%of patients were diagnosed within 7 days,97.12%of patients had never been vaccinated,and 93.66%had a clear contact history.Conclusions From 2010 to 2021,the incidence of HFRS in Xuzhou City showed a high sporadic state,mainly mild and medium,maintained at a low incidence level,and the prognosis of most cases was good.The city’s HFRS epidemic surveillance,rodent control,and health education for key populations should continue to be done.
作者
安晓红
葛小伍
李娜
AN Xiaohong;GE Xiaowu;LI Na(Xuzhou Center for Disease Control and Prevention,Xuzhou 221006,Jiangsu,China)
出处
《中国校医》
2023年第5期343-345,368,共4页
Chinese Journal of School Doctor
基金
徐州市科技项目(KC21265)
关键词
肾综合征出血热
流行病学监测
临床特征
Hemorrhagic fever with renal syn⁃drome(HFRS)
Epidemiological surveillance
Clinical char⁃acteristic
