摘要
The aminolysis of ethyl acetate was promoted significantly via continuous reaction in a tubular reactor.Npropylacetamide was thus synthesized without presence of solvent and catalyst.The optimum conditions were obtained as follows:the reaction temperature is 218℃,the reaction pressure is 3.5 MPa,the molar ratio(ethyl acetate:N-propylamine)is 1:1,and the residence time is 350 min.Accordingly,the conversion of ethyl acetate is up to94.8%.Furthermore,the kinetics of the rapid reaction stage(when the conversion of ethyl acetate is 20%-80%)can be expressed as Ink=-4629.441/T+2.1366,and the apparent activation energy is Ea=38489 J·mol-1.
The aminolysis of ethyl acetate was promoted significantly via continuous reaction in a tubular reactor.Npropylacetamide was thus synthesized without presence of solvent and catalyst.The optimum conditions were obtained as follows:the reaction temperature is 218℃,the reaction pressure is 3.5 MPa,the molar ratio（ethyl acetate:N-propylamine） is 1:1,and the residence time is 350 min.Accordingly,the conversion of ethyl acetate is up to94.8%.Furthermore,the kinetics of the rapid reaction stage（when the conversion of ethyl acetate is 20%-80%） can be expressed as Ink=-4629.44 1/T+2.1366,and the apparent activation energy is Ea=38489 J·mol-1.
基金
financial support from the National Natural Science Foundation of China(21476194)
the National Key Research and Development Program of China(2016YFB0301800).
