摘要
目的探讨糖皮质激素联合氨茶碱治疗慢阻肺急性加重期的临床疗效。方法选取2017年4月至2019年9月在我院进行治疗急性加重期慢阻肺的患者40例进行对比分析。根据患者进行治疗的时间顺序将40例患者分为研究组和参照组,每组20人。参照组患者采用布他林联合氨茶碱的治疗方案对患者进行治疗,研究组患者则采用糖皮质激素联合氨茶碱对慢阻肺急性加重期的患者进行治疗。通过对比两组患者的血气指数、并发症发生率、治疗总有效率及患者生活质量判断临床疗效。结果(1)对比两组患者的血气指数:研究组患者的血气指数明显比参照组患者优秀,差异显著(P<0.05),有统计学意义。(2)对比两组患者的并发症发生率:研究组患者的并发症发生率低于参照组患者,差异显著(P<0.05)。(3)对比两组患者的治疗效果:研究组患者的治疗效果高于参照组患者的治疗效果,差异显著(P<0.05),有统计学意义。(4)研究组患者的生活质量高于参照组患者,差异显著(P<0.05)。结论通过对比两组患者的研究数据,证明糖皮质激素联合氨茶碱治疗慢阻肺急性加重期的临床疗效良好,降低了患者的并发症发生率,提升了患者的生活质量,具有很高的临床学价值,值得临床推广使用。
Objective To explore the clinical effect of glucocorticoid combined with aminophylline in the treatment of acute exacerbation of COPD.Methods From April 2017 to September 2019,40 patients with COPD in acute exacerbation stage were selected for comparative analysis.According to the time sequence of treatment,40 patients were divided into study group and reference group,20 in each group.The patients in the reference group were treated with butaline and aminophylline,while those in the study group were treated with glucocorticoid and aminophylline.The clinical effect was evaluated by comparing the blood gas index,the incidence of complications and the total effective rate of the two groups.Results(1)Comparison of two groups of patients with blood gas index:the study group of patients with blood gas index was significantly better than the reference group,the difference was significant(P<0.05),with statistical significance.(2)Compared the incidence of complications in the two groups:the incidence of complications in the study group was lower than that in the reference group,the difference was significant(P<0.05).(3)Compared the treatment effect of two groups of patients:the treatment effect of the study group was higher than that of the reference group,the difference was significant(P<0.05),with statistical significance.(4)The quality of life in the study group was higher than that in the control group(P<0.05).Conclusion By comparing the data of the two groups of patients,it is proved that glucocorticoid combined with aminophylline has a good clinical effect in the treatment of acute exacerbation of COPD,which can reduce the incidence of complications and improve the quality of life of patients.It has a high clinical value and is worthy of clinical application.
作者
陈旋
CHEN Xuan(The First Hospital of Xuzhou Mining Group,Xuzhou,Jiangsu 221131)
出处
《智慧健康》
2020年第25期194-196,共3页
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