摘要
目的阐述高龄孕妇在妊娠中晚期阶段产检时接受唐氏筛查的作用以及价值。方法收集邗江区妇幼保健所从2019年6月-2020年12月时间段内的100例中期孕妇研究,根据年龄将其分为观察组与对照组,每组分别纳入50例孕妇。对整体100例孕妇进行唐氏筛查,并通过羊水穿刺,分析胎儿是否存在唐氏综合征,并对比相关指标。结果结果显示,观察组唐氏筛查阳性率为26%、羊水穿刺阳性率为14%,对照组唐氏筛查阳性率为10%、羊水穿刺阳性率为2%,对比发现P<0.05。观察组存在不良妊娠结局的人数为9例,所占比例为18%,对照组存在不良妊娠的人数为1例,对比发现P<0.05。观察组甲胎蛋白为(0.88±0.05)μg/L、促性腺激素为(2.76±0.31)mU/mL,对照组甲胎蛋白为1.78±0.17μg/L、促性腺激素为(1.34±0.12)mU/mL,对比观察组高于对照组,P<0.05。结论将唐氏综合征筛查用于高龄孕妇产前检查中,可以降低产妇发生不良妊娠结局的概率,并及时对其进行针对性的护理。
Objective To describe effect and value of Down’s screening for elderly pregnant women during prenatal examination in middle and third trimester of pregnancy.Methods The paper chose 100 mid-term pregnant women in Hanjiang maternal and child health center from June 2019 to December 2020,and divided them into observation group and control group according to age,with 50 pregnant women in each group.All 100 cases pregnant women were screened for Down’s syndrome and amniocentesis,to analyze possible Down’s syndrome.Relevant indexes were compared.Results Positive rates of Down’s screening and amniocentesis were 26%and 14%in observation group,10%and 2%in control group,comparison showed P<0.05.There were 9 cases with adverse pregnancy outcomes in observation group,accounting for 18%,1 case with adverse pregnancy in control group,comparison showed P<0.05.Alpha fetoprotein in observation group was(0.88±0.05)μG/L,gonadotropin was(2.76±0.31)mu/ml,and alpha fetoprotein in control group was(1.78±0.17)μG/L and gonadotropin were(1.34±0.12)mu/ml,that of observation group was higher than control group(P<0.05).Conclusion Down’s syndrome screening in can reduce probability of adverse pregnancy outcome,and provide targeted nursing in time prenatal examination of elderly pregnant women.
作者
牛家磊
NIU Jia-lei(Yangzhou City Hanjiang District Maternal and Child Health Care Center,Yangzhou,Jiangsu,225000)
出处
《智慧健康》
2021年第33期7-9,共3页
Smart Healthcare
关键词
高龄孕妇
妊娠中期
产前诊断
唐氏筛查
Elderly pregnant women
Second trimester of pregnancy
Prenatal diagnosis
Down’s screening
