摘要
目的:研究傣药“毫命”(姜黄Curcuma longa L.根茎)水提部位的化学成分。方法:采用大孔树脂柱层析、硅胶柱层析、半制备HPLC等多种色谱分离方法,对“毫命”水提部位中的成分进行分离纯化,根据理化性质和波谱数据对所得化合物进行结构鉴定。结果:从“毫命”水提部位中分离得到11个化合物,分别鉴定为:longpene E(1)、香草醇(2)、姜黄素(3)、去甲氧基姜黄素(4)、双去甲氧基姜黄素(5)、甜没药姜黄醇(6)、甜没药姜黄醇B(7)、intermedin B(8)、longpene C(9)、赤式-愈创木基甘油-β-松柏基醚(10)、新橄榄树脂素(11)。结论:其中,化合物1为新化合物,化合物10、11为首次从该植物中分离得到。
Objective:To study the chemical constituents of water extraction from the Dai medicine"Haoming"(Curcuma longa rhizome).Methods:The various chromatographic techniques,such as macro-porous resin,silica gel column chromatography and semiprep HPLC were used to isolate and purify compounds from the water extraction of Curcuma longa rhizome,the structures of these compounds were identified by analysis of physicochemical property and spectroscopic data.Results:Eleven compounds were isolated from water extraction of Curcuma longa rhizome and identified as longpene E(1),citronellol(2),curcumin(3),demethoxycurcumin(4),bisdemethoxycurcumin(5),bisacurone(6),bisacurone B(7),intermedin B(8),longpene C(9),erythro-guaiacylglycerol-β-coniferyl ether(10),neoolivil(11),respectively.Conclusion:Among them,compound 1 is a new compound,compounds 10,11 are isolated from Curcuma longa rhizome for the first time.
作者
张莹莹
覃香世
陈绍田
徐雨
吕小满
陈佳
ZHANG Ying-ying;QIN Xiang-shi;CHEN Shao-tian;XU Yu;LYU Xiao-man;CHEN Jia(Yunnan University of Chinese Medicines/Yunnan Key Laboratory of Dai and Yi Medicines,Kunming 650500,China;Kunming Institute of Botany,Chinese Academy of Sciences/Southwest China Germplasm Bank of Wildlife,Kunming 650201,China)
出处
《中药材》
CAS
北大核心
2023年第5期1156-1160,共5页
Journal of Chinese Medicinal Materials
基金
国家自然科学基金委员会地区基金项目(82060785)
云南省科技厅基础研究计划中医联合项目面上项目(202001AZ070001-027)
云南省傣医药与彝医药重点实验室开放课题(202210JS2201)
关键词
傣药
姜黄
水提取部位
化学成分
Dai medicines
Curcuma longa L.
Water extraction
Chemical constituents
