摘要
目的探讨对慢性鼻-鼻窦炎患者采用轮廓化鼻内镜手术治疗的临床效果及对改善鼻黏液纤毛清除功能与血清炎性因子水平的作用。方法选择我院2019年5月至2021年6月收治慢性鼻-鼻窦炎患者65例,按照手术方式不同分为2组,对照组(n=32)采用功能性鼻内镜手术治疗,实验组(n=33)采用轮廓化鼻内镜手术治疗,比较两组临床疗效,与治疗前、治疗3月后通过糖精实验评估患者鼻黏液纤毛清除功能,并检测患者C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)水平评估患者血清炎性因子的变化。结果实验组治疗总有效率高于对照组;治疗3月后,实验组黏液纤毛清除速度、清除率大于对照组;糖精清除时间短于对照组;CRP、TNF-α水平小于对照组;差异有统计学意义(P<0.05)。结论对慢性鼻-鼻窦炎患者采用轮廓化鼻内镜手术治疗效果理想,能够有效改善患者的鼻黏液纤毛清除功能,且可减轻机体炎性反应,值得推广。
Objective To investigate the clinical effect of contour nasal endoscopic surgery and improving the nasal mucocilia clearance function and serum inflammatory factors.Methods We selected 65 patients with chronic rhino-sinusitis from May 2019 to June 2021,which were divided into two groups.Control groups(n=32)used functional nasal endoscopic surgery,experimental group(n=33)used contour nasal endoscopic surgical treatment,compared the clinical efficacy of the two groups,and evaluated the serum nasal mucinous cilia clearance function by saccharin experiments,and tested C response protein(CRP)and tumor necrosis factor-(TNF-).Results The total treatment efficiency of the experimental group was higher than the control group;after March of treatment,mucocilia clearance rate of the experimental group was greater than that;saccharin clearance time was shorter than the control group;CRP and TNF-level were less than the control group;statistically significant(P<0.05).Conclusion Outline nasal endoscopic surgery can effectively improve the nasal mucinous cilia clearance function and reduce the inflammatory response,which is worth promoting.
作者
陈丽
Chen Li(Department of Otolaryngology,Hongze District People’s Hospital of Huai’an City,Jiangsu Huai’an,223100,China)
出处
《中国医学文摘（耳鼻咽喉科学）》
2023年第1期49-51,28,共4页
Chinese Medical Digest(Otorhinolaryngology)
关键词
慢性鼻-鼻窦炎
功能性鼻内镜手术
轮廓化鼻内镜手术
鼻黏液纤毛清除功能
血清炎性因子
Chronic nasal-sinusitis
Functional nasal endoscopic surgery
Contour nasal endoscopic surgery
Nasal mucinous ciliary clearance function
Serum inflammatory factors
