摘要
目的探讨增加压迫系数(ICF)的角膜塑形镜矫正儿童近视眼的有效性和安全性。方法前瞻性队列研究。连续收集2016年5月至2018年12月在成都医学院第一附属医院眼科门诊验配角膜塑形镜的近视眼患儿资料, 纳入右眼进行研究。依据患儿情况验配角膜塑形镜, 近视度数<3.00 D者为低度近视, ≥3.00 D者为中度近视, 低度和中度近视的患儿分别采用Excel随机数分为低度近视试验组、低度近视对照组和中度近视试验组、中度近视对照组, 分别验配ICF和常规压迫系数的角膜塑形镜。对比各组戴镜1年期间的眼轴长度、等效球镜度数(SE)、最佳矫正视力(BCVA)、近视力、眼前节情况(Efron分级)、角膜滞后量(CH)、角膜阻力因子(CRF)、角膜补偿眼压(IOPcc)、泪膜破裂时间(BUT)、高阶像差、调节幅度和调节灵敏度(AF)。分类资料采用χ2检验, 计量资料采用独立样本t检验。结果戴镜1年后, 低度近视试验组与低度近视对照组的AL、SE、BCVA、NVA、Efron分级、CH、CRF、IOPcc、BUT、高阶像差、调节幅度和AF的差异均无统计学意义(均P>0.05)。戴镜6个月后, 中度近视试验组眼轴长度增加了(0.05±0.03)mm, 与中度近视对照组的(0.08±0.04)mm相比, 差异有统计学意义(t=-3.416, P=0.001)。戴镜1年后, 中度近视试验组眼轴长度增加了(0.12±0.04)mm, 与中度近视对照组的(0.16±0.05)mm相比, 差异有统计学意义(t=-4.017, P<0.001);中度近视试验组的SE为(-0.16±0.40)D, 与中度近视对照组的(-0.58±0.60)D相比, 差异有统计学意义(t=3.529, P=0.001);两组总高阶像差、球差及AF的差异亦有统计学意义(均P<0.05), 而两组BCVA、近视力、眼前节情况、CH、CRF、IOPcc、BUT及调节幅度的差异均无统计学意义(均P>0.05)。结论 ICF角膜塑形镜在观察期内能够安全有效地矫正儿童近视眼, 对中度近视眼的进展控制效果更好。
Objective To discuss the efficacy and safety of orthokeratology with increased compression factor(ICF)in myopia correction in children.Methods It was a prospective cohort study.Data of the right eyes of myopic children who visited the First Affiliated Hospital of Chengdu Medical College for orthokeratology were collected continuously from May 2016 to Dec 2018.All children had low myopia(<3.00 D)or moderate myopia(≥3.00 D),and were grouped using random numbers in Excel to receive orthokeratology with ICF or conventional compression factor(CCF).The axial length(AL),spherical equivalent(SE),best corrected visual acuity(BCVA),near visual acuity(NVA),Efron grade,corneal hysteresis(CH),corneal resistance factor(CRF),corneal-compensated intraocular pressure(IOPcc),tear film break-up time(BUT),higher-order aberrations(HOAs),accommodative amplitude(AA)and accommodative facility(AF)were compared between groups during the 1-year treatment period.The Chi-squared test was used to compare the categorical data,while the independent-sample t-test was performed to assess the measurement data.Results After 1 year of treatment,there were no statistical differences in AL,SE,BCVA,NVA,Efron grade,CH,CRF,IOPcc,BUT,HOAs,AA and AF between the low myopia ICF group and the low myopia CCF group(all P>0.05).After 6 months of treatment,the AL increased by(0.05±0.03)mm in the moderate myopia ICF group and by(0.08±0.04)mm in the moderate myopia CCF group(t=-3.416,P=0.001).After 1 year of treatment,the AL increased by(0.12±0.04)mm in the moderate myopia ICF group and by,(0.16±0.05)mm in the moderate myopia CCF group(t=-4.017,P<0.001).The SE was(-0.16±0.40)D in the moderate myopia ICF group,significantly different from that in the moderate myopia CCF group[(-0.58±0.60)D;t=3.529,P=0.001].There were also statistical differences in HOAs,spherical aberrations and AF(all P<0.05),but no statistical differences in BCVA,NVA,Efron grade,CH,CRF,IOPcc,BUT and AA between the two groups(all P>0.05).Conclusions Orthokeratology with ICF safely and effec
作者
唐文婷
李佳倩
李世贝
唐勇军
马丁鹏
Tang Wenting;Li Jiaqian;Li Shibei;Tang Yongjun;Ma Dingpeng(Department of Ophthalmology,the First Affiliated Hospital of Chengdu Medical College,Chengdu 610500,China;Department of Ophthalmology,the People′s Hospital of Songpan County,Aba Tibetan Qiang Autonomous Prefecture 623300,China)
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2022年第11期907-913,共7页
Chinese Journal of Ophthalmology
基金
四川省教育厅项目(15ZA0262)。
关键词
近视
接触镜
角膜塑形术
结果可重复性
增强压迫系数
Myopia
Contact lenses
Orthokeratologic procedures
Reproducibility of results
increased compression factor
