摘要
目的探讨核磁共振表现颞叶内侧信号异常的神经梅毒的临床特征。方法通过总结本院近期收治的1例及国内外文献报道确诊的28例核磁共振表现为颞叶内侧信号异常患者的临床资料,分析该病的临床特点。结果患者主要表现为认知障碍、癫痫、精神行为异常等。影像学检查与边缘叶脑炎典型征象无明显差别。血清及CSF梅毒特异性检查阳性。结论神经梅毒与边缘叶脑炎有相似临床表现及影像学征象,确诊需检查梅毒特异性抗体。尽早青霉素或头孢曲松治疗可显著改善预后。
Objective To explore the clinical features of neurosyphilis with mesiotemporal changes on magnetic resonance imaging.Methods By analyzing one recent case of neurosyphilis with mesiotemporal changes on magnetic resonance imaging in our hospital and 28 cases reported in the literature,the clinical features of the disease were summarized.Results The clinical manifestations of the disease were cognitive impairment,psychiatric disorders and seizures.The MRI changes seen in limbic-like neurosyphilis and neurosyphilis were indistinguishable.Treponemal and nontreponemal test in serum and CSF was positive.Conclusion Neurosyphilis and limbic-like encephalitis had similar clinical features and sign of MRI,apositive treponemal and nontreponemal test in serum and CSF was required to make the diagnosis.The early treatment of penicillin or ceftriaxone could significantly improve the prognosis.
作者
刘佳琪
周翠萍
孙阳
刘芳
Liu Jiaqi;Zhou Cui ping;Sun Yang(Department of Neurology,Beijing Huaxin Hospital（The First Hospital of Tsinghua University）,Beijing 100016)
出处
《卒中与神经疾病》
2018年第5期562-566,571,共6页
Stroke and Nervous Diseases
关键词
神经梅毒
脑炎
影像学
颞叶内侧
Neurosyphilis
Encephalitis
MRI imaging
Mesiotemporal changes
