摘要
体外受精-胚胎移植（in vitro fertilization-embryo transfer, IVF-ET）技术发展最开始,大多数采用的受精方法是每个卵子加2～5万精子体外培养16～18 h进行受精,即常规的过夜受精法.在20世纪末开始大量报道,采用短时受精（2～4 h）较常规过夜受精可以提高优质胚胎率,从而提高妊娠率[1,2].我中心自2001年IVF-ET助孕采用短时受精,现将短时受精和常规过夜受精两者助孕情况报道如下.
Objective： To investigate the effect of short co-incubation of gametes on the outcomes of in vitro fertilization-embryo transfer （IVF-ET）. Methods： The clinical date of 2,044 IVF-ET cycles with short gamete co-incubation （2 h） in IVF and 274 cycles with conventional overnight co-incubation were analyzed retrospectively. Results： The lower fertilization rate and higher polyspermic fertilization rate were found in the group of short co-incubation of gametes than those in the group of overnight fertilization, and the difference was significant （P〈0.01）. No significant difference was found in cleavage rate, high-quality embryo rate, im plantation rate, pregnancy rate, miscarriage rate or ectopic pregnancy rate between the two groups. Conclusion： Short co-incubation of gametes in IVF treatment may increase the polyspermic fertilization rate.
出处
《生殖医学杂志》
CAS
2011年第2期85-87,共3页
Journal of Reproductive Medicine
关键词
短时受精
体外受精-胚胎移植
多精受精
Short gamete co-incubation
fertilization In vitro fertilization-embryo transfer
Polyspermic
