摘要
多糖是重要的药用活性成分,具有抗肿瘤、抗凝血和免疫调节活性等多种功能,而多糖的分子修饰能够提高它原有的活性或增加新的活性.本文详细阐述了多糖的硫酸化、磷酸化、乙酰化等分子修饰及其对生物活性的影响,最后对多糖的分子修饰及其应用进行了展望.
Polysaccharides are the important medicine ingredient,which play significant role in anti-tumor,immunity modulation and anticoagulation.The structural modification of polysaccharides can not only enhance their intrinsic activities,but also increase the undiscovered activities.In this paper,the methods of structural modification such as sulfation,phosphorylation and acylation in polysaccharides and their influence on biological activity are introduced,and then the structural modification and application of p...
出处
《贵州科学》
2008年第3期66-71,共6页
Guizhou Science
基金
贵州省优秀科教人才省长基金
贵州省自然科学基金(基合字(1999)3105)
关键词
多糖
分子修饰
生物活性
polysaccharide
molecular modification
biological activities
