牙周病和植体周病国际分类研讨会于2017年11月9至11日在美国芝加哥举行,100余名来自世界各地的参会者对1999年的牙周病分类进行修订,提出牙周炎的新分类框架,并参照牙周病分类的方案首次制定了植体周病和状况的分类。与会专家还提出了...牙周病和植体周病国际分类研讨会于2017年11月9至11日在美国芝加哥举行,100余名来自世界各地的参会者对1999年的牙周病分类进行修订,提出牙周炎的新分类框架,并参照牙周病分类的方案首次制定了植体周病和状况的分类。与会专家还提出了病例定义(case definitions),提供了诊断标准以便于临床医师使用。2017年研讨会达成的4篇共识报告和相关领域的19篇综述于2018年6月正式发表在美国牙周学会主办的牙周病学杂志(Journal of Periodontology)和欧洲牙周联盟主办的临床牙周病学杂志(Journal of Clinical Periodontology)特刊上。本文简介了牙周病和植体周病及状况的新分类,并针对1999年分类的主要变化进行重点阐述。展开更多
This paper focused on the relationship between periodontitis and Type 2 diabetes mellitus (T2DM). There is an abundance of evidence that diabetes mellitus play important etiological roles in periodontal diseases. In a...This paper focused on the relationship between periodontitis and Type 2 diabetes mellitus (T2DM). There is an abundance of evidence that diabetes mellitus play important etiological roles in periodontal diseases. In addition, periodontal diseases have powerful and multiple influences on the occurrence and severity of systemic conditions and diseases, such as diabetes mellitus, cardiovascular disease, respiratory disease and pregnancy complications. The relationship of periodontitis and diabetes has been supported by sufficient evidences in the past twenty years: (1) diabetes is an independent risk factor of chronic periodontitis; (2) metabolic control will improve the prognosis of chronic periodontitis; (3) the treatment of chronic periodontitis will improve the metabolic level. Our recent investigation on periodontal status in the families of type 2 diabetes mellitus further confirmed the relationship. It was showed that the periodontal index such as probing depth (PD), attachment loss (AL) and numbers of tooth loss in diabetes family members were significantly higher than non-diabetes family members, while no difference of periodontal parameters was found between well control family members and non diabetes family members. In the development of type 2 diabetes (T2DM) and its complications, the advanced glycation end products (AGEs) and its receptors were to be recognized as important factors. The distributions of AGEs and the receptor for AGEs (RAGE) are highly consistent in various tissues. One study in our laboratory demonstrated that RAGE was strongly expressed in gingival tissues gathered from T2DM patients with periodontitis compared with systemically healthy chronic periodontitis patients, the expression of RAGE was positively correlated with the expression of TNF-α, indicating that AGE-RAGE pathway was involved in the development of periodontitis in T2DM patients. It is known that inflammation could induce the prediabetic status characterized by insulin resistance and dyslipidemia. However, it is still 展开更多
文摘牙周病和植体周病国际分类研讨会于2017年11月9至11日在美国芝加哥举行,100余名来自世界各地的参会者对1999年的牙周病分类进行修订,提出牙周炎的新分类框架,并参照牙周病分类的方案首次制定了植体周病和状况的分类。与会专家还提出了病例定义(case definitions),提供了诊断标准以便于临床医师使用。2017年研讨会达成的4篇共识报告和相关领域的19篇综述于2018年6月正式发表在美国牙周学会主办的牙周病学杂志(Journal of Periodontology)和欧洲牙周联盟主办的临床牙周病学杂志(Journal of Clinical Periodontology)特刊上。本文简介了牙周病和植体周病及状况的新分类,并针对1999年分类的主要变化进行重点阐述。
文摘This paper focused on the relationship between periodontitis and Type 2 diabetes mellitus (T2DM). There is an abundance of evidence that diabetes mellitus play important etiological roles in periodontal diseases. In addition, periodontal diseases have powerful and multiple influences on the occurrence and severity of systemic conditions and diseases, such as diabetes mellitus, cardiovascular disease, respiratory disease and pregnancy complications. The relationship of periodontitis and diabetes has been supported by sufficient evidences in the past twenty years: (1) diabetes is an independent risk factor of chronic periodontitis; (2) metabolic control will improve the prognosis of chronic periodontitis; (3) the treatment of chronic periodontitis will improve the metabolic level. Our recent investigation on periodontal status in the families of type 2 diabetes mellitus further confirmed the relationship. It was showed that the periodontal index such as probing depth (PD), attachment loss (AL) and numbers of tooth loss in diabetes family members were significantly higher than non-diabetes family members, while no difference of periodontal parameters was found between well control family members and non diabetes family members. In the development of type 2 diabetes (T2DM) and its complications, the advanced glycation end products (AGEs) and its receptors were to be recognized as important factors. The distributions of AGEs and the receptor for AGEs (RAGE) are highly consistent in various tissues. One study in our laboratory demonstrated that RAGE was strongly expressed in gingival tissues gathered from T2DM patients with periodontitis compared with systemically healthy chronic periodontitis patients, the expression of RAGE was positively correlated with the expression of TNF-α, indicating that AGE-RAGE pathway was involved in the development of periodontitis in T2DM patients. It is known that inflammation could induce the prediabetic status characterized by insulin resistance and dyslipidemia. However, it is still
