基金supported by the National Key Research and Development Program of China(No.2020YFC2004405)the National Natural Science Foundation of China(No.8201101103,81870506,91849208,81670676,and 81422011)+4 种基金Project of Traditional Chinese Medicine in Guangdong Province(No.20201062)Basic Research Project of Shenzhen Science and Technology Innovation Committee(No.JCYJ20180306174648342 and JCYJ20190808102005602)Shenzhen Futian District Public Health Research Project(No.FTWS2019003)the Shenzhen Key Medical Discipline Construction Fund(No.SZXK002)to HUANG Huisupported by the National Natural Science Foundation of China(No.82073408)to CHEN Jie