Objective： To observe the clinical efficacy of acupuncture plus motor therapy for postapoplectic spastic hemiplegia and provide reference for rehabilitation care of patients with spastic hemiplegia after stroke. Meth...Objective： To observe the clinical efficacy of acupuncture plus motor therapy for postapoplectic spastic hemiplegia and provide reference for rehabilitation care of patients with spastic hemiplegia after stroke. Methods： A total of 87 cases with postapoplectic spastic hemiplegia were randomly allocated into a treatment group and a control group. Patients in both groups received basic treatments to control blood pressure, blood sugar, blood fat and improve circulation. The 43 cases in the treatment group received acupuncture combined with motor therapy, whereas the 44 cases in the control group received motor therapy alone（same as the treatment group）. The treatment was conducted once a day, for a total of 3 sessions. One session consisted of 10 times and there was a 1-day interval between two sessions. Then the changes in modified Ashworth scale（MAS） score and Fugl-Meyer assessment scale（FMA） score and clinical efficacy were observed. Results： After treatment, the MAS scores were significantly decreased in both groups, showing intra-group statistical differences（P〈0.01）. The MAS score in the treatment group was significantly lower than that in the control group, showing a between-group statistical difference（P〈0.01）. The total effective rate was 69.8% in the treatment group, versus 45.5% in the control group, showing a between-group statistical difference（P〈0.05）. After treatment, the FMA scores were significantly increased in both groups, showing intra-group statistical differences（P〈0.01）; and the FMA score in the treatment group was significantly higher than that in the control group, showing a between-group statistical difference（P〈0.05）. Conclusion： Acupuncture combined with motor therapy is better than motor therapy alone in alleviating postapoplectic limb spasticity, improving the limb motor function and increasing the activities of daily living（ADL）.展开更多
Objective：To observe the effect of Governor Vessel-unblocking and mind-calming acupuncture on insomnia and further develop the academic idea on Gao＇s lineage acupuncture.Methods：A total of 68 insomnia cases were ra...Objective：To observe the effect of Governor Vessel-unblocking and mind-calming acupuncture on insomnia and further develop the academic idea on Gao＇s lineage acupuncture.Methods：A total of 68 insomnia cases were randomly allocated into an acupuncture group（n=34） and a medication group（n=34） according to their sequences of consultation.Patients in the acupuncture group received acupuncture treatment once a day,5 d a week,for 4 weeks.Patients in the medication group took 1 mg of Estazolam before sleep for each dose,one dose a day,for 4 weeks.Before and after treatment,the sleep quality was evaluated using the Pittsburgh sleep quality index（PSQI）,and the efficacy was assessed using the PSQI reductive rate.Results：After treatment,the global PSQI score and scores of each component in the acupuncture group were significantly decreased（all P〈0.01）.The global PSQI score in the medication group was significantly decreased（P〈0.01）.Except for sleep disturbance,scores of the rest of components were significantly decreased（P〈0.01 or P〈0.05）.The between-group difference was statistically significant in global PSQI score（P〈0.01）.Except for sleep latency and duration,scores of the sleep quality,efficiency,disturbance and daytime dysfunction in the acupuncture group were significantly lower than those in the medication group（all P〈0.05）.In addition,the recovery and marked effect rate in the acupuncture group was significantly higher than that in the medication group（P〈0.05）.Conclusion：The Governor Vessel-unblocking and mind-calming acupuncture is safe,reliable for insomnia and has better efficacy than Estazolam.展开更多
Objective:To observe the short-and long-term clinical efficacy differences of body acupuncture and scalp acupuncture combined with extracorporeal shock wave and simple extracorporeal shock wave.Methods:Sixty patients ...Objective:To observe the short-and long-term clinical efficacy differences of body acupuncture and scalp acupuncture combined with extracorporeal shock wave and simple extracorporeal shock wave.Methods:Sixty patients with scapulohumeral periarthritis were randomly divided into two groups:the treatment group and control group,30 cases in each one.Both groups underwent basic rehabilitation training.Patients in the treatment group were treated with body acupuncture and scalp acupuncture combined with extracorporeal shock wave.Yújì(鱼际 LU10),Hégǔ(合谷L14),Zhōngzhǔ(中渚TE3),Hòuxī(后溪SI3).There were three needles for the scalp acupuncture with the first between Shéntíng(神庭 GV24)and Yìntáng(印堂 EX-HN3),and the other two straightly through the inner canthus and parallel to the first needle.Shock wave treatment was intensively applied in some pressure points around shoulder joint.The control group used the same shock wave therapy as the treatment group.Both groups were all treated once a day,6 times a week.Patients were treated for one course which lasted for 4 weeks.VAS score,the Constant-Murley score and the HAMA(the Hamilton Anxiety Scale)are as therapeutic effect index.30 days telephone investigation followed-up after the treatment course was evaluated.Results:Totally 28 cases completed the clinical observation in the treatment group,and 29 cases in the control group.The total effective rate of the treatment group was 85.7%(24/28),which was higher than 69.0%(20/29)of the control group(P<0.05).VAS score:There were significant statistical differences before and after the treatment in the two groups(the treatment group:6.67 ± 1.43 vs 3.47 ± 1.35,the control group:7.57 ± 1.31 vs 5.36 ± 1.45,both P<0.05).There were significant statistical differences before the treatment and at the follow-up in the two groups(the treatment group:6.67 ± 1.43 vs2.68±0.81,the control group:7.57±1.31 vs 4.56±1.35,both P<0.05).The VAS scores of the treatment group after treatment and at the follow-up were re展开更多
BACKGROUND Although hepatocellular carcinoma(HCC) is one of the most vascular solid tumors, antiangiogenic therapy has not induced the expected results.AIM To uncover immunohistochemical(IHC) aspects of angiogenesis i...BACKGROUND Although hepatocellular carcinoma(HCC) is one of the most vascular solid tumors, antiangiogenic therapy has not induced the expected results.AIM To uncover immunohistochemical(IHC) aspects of angiogenesis in HCC.METHODS A retrospective cohort study was performed and 50 cases of HCC were randomly selected. The angiogenesis particularities were evaluated based on the IHC markers Cyclooxygenase-2(COX-2), vascular endothelial growth factor(VEGF) A and the endothelial area(EA) was counted using the antibodies CD31 and CD105.RESULTS The angiogenic phenotype evaluated with VEGF-A was more expressed in small tumors without vascular invasion(pT1), whereas COX-2 was rather expressed in dedifferentiated tumors developed in non-cirrhotic liver. The CD31-related EA value decreased in parallel with increasing COX-2 intensity but was higher in HCC cases developed in patients with cirrhosis. The CD105-related EA was higher in tumors developed in patients without associated hepatitis.CONCLUSION In patients with HCC developed in cirrhosis, the newly formed vessels are rather immature and their genesis is mediated via VEGF. In patients with non-cirrhotic liver, COX-2 intensity and number of mature neoformed vessels increases in parallel with HCC dedifferentiation.展开更多
The deleterious effects of long-term right ventricular pacing necessitated the search for alternative pacing sites which could prevent or alleviate pacinginduced cardiomyopathy.Until recently,biventricular pacing(BiVP...The deleterious effects of long-term right ventricular pacing necessitated the search for alternative pacing sites which could prevent or alleviate pacinginduced cardiomyopathy.Until recently,biventricular pacing(BiVP)was the only modality which could mitigate or prevent pacing induced dysfunction.Further,BiVP could resynchronize the baseline electromechanical dssynchrony in heart failure and improve outcomes.However,the high non-response rate of around 20%-30%remains a major limitation.This non-response has been largely attributable to the direct non-physiological stimulation of the left ventricular myocardium bypassing the conduction system.To overcome this limitation,the concept of conduction system pacing(CSP)came up.Despite initial success of the first CSP via His bundle pacing(HBP),certain drawbacks including lead instability and dislodgements,steep learning curve and rapid battery depletion on many occasions prevented its widespread use for cardiac resynchronization therapy(CRT).Subsequently,CSP via left bundle branch-area pacing(LBBP)was developed in 2018,which over the last few years has shown efficacy comparable to BiVP-CRT in small observational studies.Further,its safety has also been well established and is largely free of the pitfalls of the HBP-CRT.In the recent metanalysis by Yasmin et al,comprising of 6 studies with 389 participants,LBBPCRT was superior to BiVP-CRT in terms of QRS duration,left ventricular ejection fraction,cardiac chamber dimensions,lead thresholds,and functional status amongst heart failure patients with left bundle branch block.However,there are important limitations of the study including the small overall numbers,inclusion of only a single small randomized controlled trial(RCT)and a small follow-up duration.Further,the entire study population analyzed was from China which makes generalizability a concern.Despite the concerns,the meta-analysis adds to the growing body of evidence demonstrating the efficacy of LBBP-CRT.At this stage,one must acknowledge that the fact that stil展开更多
Objective： To observe the instant analgesic effect of Governor Vessel-regulating and collateral-unblocking acupuncture method in treating primary headache and to inherit and carry forward the academic achievements of...Objective： To observe the instant analgesic effect of Governor Vessel-regulating and collateral-unblocking acupuncture method in treating primary headache and to inherit and carry forward the academic achievements of Gao＇s acupuncture school in Yanzhao （Hebei Province） area. Methods： Eighty eligible primary headache patients were randomized into an observation group and a control group following their visiting sequence, 40 patients in each group. The observation group was intervened by Yanzhao Gao＇s Governor Vessel-regulating and collateral-unblocking acupuncture, and the control group was intervened by ordinary acupuncture method. The visual analogue scale （VAS） was used to evaluate the headache intensity before and after the first treatment session in the two groups, to compare the instant analgesic effect of the two acupuncture methods. Results： After the first treatment session, the VAS scores dropped significantly in both groups （both P〈0.05）. The change of VAS score after the initial treatment in the observation group was significantly different from that in the control group （P〈0.05）. The percentage of patients with headache completely vanished instantly after the first treatment was markedly higher in the observation group than that in the control group （P〈0.05）. Conclusion： The two acupuncture methods both can produce a significant instant analgesic effect in treating primary headache, while Yanzhao Gao＇s Governor Vessel-regulating and collateral-unblocking acupuncture method is superior to ordinary acupuncture method.展开更多
BACKGROUND Fourth degree burns damage the full thickness of the skin and affect underlying tissues.Skin grafting after debridement is often used to cover the wounds of salvageable severe burns.A granulation wound can ...BACKGROUND Fourth degree burns damage the full thickness of the skin and affect underlying tissues.Skin grafting after debridement is often used to cover the wounds of salvageable severe burns.A granulation wound can be formed by drilling the skull to the barrier layer to solve the problem of skull exposure.Low oxygen levels present at high altitudes aggravate ischemia and hypoxia which can negatively impact wound healing.The impaired healing in such cases can be ameliorated by hyperbaric oxygen therapy.CASE SUMMARY We describe a patient who presented with fourth degree burns to the left temporal and facial regions upon admission in December 2018.The periosteum of the skull and the deep fascia of the face were exposed.After the first stage of debridement and skin grafting,the temporal skin did not survive well.Granulation was induced by cranial drilling,and then a local flap was transferred to cover the wound.The left temporal and facial wounds were completely covered and the patient recovered well.CONCLUSION Skin grafting and flap transfer after early debridement to cover the wound and control infection were of great significance.In the later stages of the patient's treatment,survival of the skin graft and skin flap was observed.The second stage repair was performed to achieve successful skin grafting by cranial granulation.Granulation was formed by drilling the skull,and then the wound was closed,which is suitable for cases with skull exposure and wounds with poor blood supply.We consider that hyperbaric oxygen treatment and improving tissue oxygen supply were beneficial in this patient.展开更多
文摘Objective： To observe the clinical efficacy of acupuncture plus motor therapy for postapoplectic spastic hemiplegia and provide reference for rehabilitation care of patients with spastic hemiplegia after stroke. Methods： A total of 87 cases with postapoplectic spastic hemiplegia were randomly allocated into a treatment group and a control group. Patients in both groups received basic treatments to control blood pressure, blood sugar, blood fat and improve circulation. The 43 cases in the treatment group received acupuncture combined with motor therapy, whereas the 44 cases in the control group received motor therapy alone（same as the treatment group）. The treatment was conducted once a day, for a total of 3 sessions. One session consisted of 10 times and there was a 1-day interval between two sessions. Then the changes in modified Ashworth scale（MAS） score and Fugl-Meyer assessment scale（FMA） score and clinical efficacy were observed. Results： After treatment, the MAS scores were significantly decreased in both groups, showing intra-group statistical differences（P〈0.01）. The MAS score in the treatment group was significantly lower than that in the control group, showing a between-group statistical difference（P〈0.01）. The total effective rate was 69.8% in the treatment group, versus 45.5% in the control group, showing a between-group statistical difference（P〈0.05）. After treatment, the FMA scores were significantly increased in both groups, showing intra-group statistical differences（P〈0.01）; and the FMA score in the treatment group was significantly higher than that in the control group, showing a between-group statistical difference（P〈0.05）. Conclusion： Acupuncture combined with motor therapy is better than motor therapy alone in alleviating postapoplectic limb spasticity, improving the limb motor function and increasing the activities of daily living（ADL）.
基金supported by Project of Hebei Provincial Administration of Traditional Chinese Medicine(No.2015011)~~
文摘Objective：To observe the effect of Governor Vessel-unblocking and mind-calming acupuncture on insomnia and further develop the academic idea on Gao＇s lineage acupuncture.Methods：A total of 68 insomnia cases were randomly allocated into an acupuncture group（n=34） and a medication group（n=34） according to their sequences of consultation.Patients in the acupuncture group received acupuncture treatment once a day,5 d a week,for 4 weeks.Patients in the medication group took 1 mg of Estazolam before sleep for each dose,one dose a day,for 4 weeks.Before and after treatment,the sleep quality was evaluated using the Pittsburgh sleep quality index（PSQI）,and the efficacy was assessed using the PSQI reductive rate.Results：After treatment,the global PSQI score and scores of each component in the acupuncture group were significantly decreased（all P〈0.01）.The global PSQI score in the medication group was significantly decreased（P〈0.01）.Except for sleep disturbance,scores of the rest of components were significantly decreased（P〈0.01 or P〈0.05）.The between-group difference was statistically significant in global PSQI score（P〈0.01）.Except for sleep latency and duration,scores of the sleep quality,efficiency,disturbance and daytime dysfunction in the acupuncture group were significantly lower than those in the medication group（all P〈0.05）.In addition,the recovery and marked effect rate in the acupuncture group was significantly higher than that in the medication group（P〈0.05）.Conclusion：The Governor Vessel-unblocking and mind-calming acupuncture is safe,reliable for insomnia and has better efficacy than Estazolam.
基金Supported by Key scientific research project of Heilongjiang administration of traditional Chinese medicine:No.ZHY18-065Inheritance studio project of national fa-mous traditional Chinese medicine experts Sun Yuanzheng,National education of traditional Chinese medicine:No.[2014]20Postgraduate innovative research project of Heilongjiang University of traditional Chinese medicine:No.2018yjscx047
文摘Objective:To observe the short-and long-term clinical efficacy differences of body acupuncture and scalp acupuncture combined with extracorporeal shock wave and simple extracorporeal shock wave.Methods:Sixty patients with scapulohumeral periarthritis were randomly divided into two groups:the treatment group and control group,30 cases in each one.Both groups underwent basic rehabilitation training.Patients in the treatment group were treated with body acupuncture and scalp acupuncture combined with extracorporeal shock wave.Yújì(鱼际 LU10),Hégǔ(合谷L14),Zhōngzhǔ(中渚TE3),Hòuxī(后溪SI3).There were three needles for the scalp acupuncture with the first between Shéntíng(神庭 GV24)and Yìntáng(印堂 EX-HN3),and the other two straightly through the inner canthus and parallel to the first needle.Shock wave treatment was intensively applied in some pressure points around shoulder joint.The control group used the same shock wave therapy as the treatment group.Both groups were all treated once a day,6 times a week.Patients were treated for one course which lasted for 4 weeks.VAS score,the Constant-Murley score and the HAMA(the Hamilton Anxiety Scale)are as therapeutic effect index.30 days telephone investigation followed-up after the treatment course was evaluated.Results:Totally 28 cases completed the clinical observation in the treatment group,and 29 cases in the control group.The total effective rate of the treatment group was 85.7%(24/28),which was higher than 69.0%(20/29)of the control group(P<0.05).VAS score:There were significant statistical differences before and after the treatment in the two groups(the treatment group:6.67 ± 1.43 vs 3.47 ± 1.35,the control group:7.57 ± 1.31 vs 5.36 ± 1.45,both P<0.05).There were significant statistical differences before the treatment and at the follow-up in the two groups(the treatment group:6.67 ± 1.43 vs2.68±0.81,the control group:7.57±1.31 vs 4.56±1.35,both P<0.05).The VAS scores of the treatment group after treatment and at the follow-up were re
文摘BACKGROUND Although hepatocellular carcinoma(HCC) is one of the most vascular solid tumors, antiangiogenic therapy has not induced the expected results.AIM To uncover immunohistochemical(IHC) aspects of angiogenesis in HCC.METHODS A retrospective cohort study was performed and 50 cases of HCC were randomly selected. The angiogenesis particularities were evaluated based on the IHC markers Cyclooxygenase-2(COX-2), vascular endothelial growth factor(VEGF) A and the endothelial area(EA) was counted using the antibodies CD31 and CD105.RESULTS The angiogenic phenotype evaluated with VEGF-A was more expressed in small tumors without vascular invasion(pT1), whereas COX-2 was rather expressed in dedifferentiated tumors developed in non-cirrhotic liver. The CD31-related EA value decreased in parallel with increasing COX-2 intensity but was higher in HCC cases developed in patients with cirrhosis. The CD105-related EA was higher in tumors developed in patients without associated hepatitis.CONCLUSION In patients with HCC developed in cirrhosis, the newly formed vessels are rather immature and their genesis is mediated via VEGF. In patients with non-cirrhotic liver, COX-2 intensity and number of mature neoformed vessels increases in parallel with HCC dedifferentiation.
文摘The deleterious effects of long-term right ventricular pacing necessitated the search for alternative pacing sites which could prevent or alleviate pacinginduced cardiomyopathy.Until recently,biventricular pacing(BiVP)was the only modality which could mitigate or prevent pacing induced dysfunction.Further,BiVP could resynchronize the baseline electromechanical dssynchrony in heart failure and improve outcomes.However,the high non-response rate of around 20%-30%remains a major limitation.This non-response has been largely attributable to the direct non-physiological stimulation of the left ventricular myocardium bypassing the conduction system.To overcome this limitation,the concept of conduction system pacing(CSP)came up.Despite initial success of the first CSP via His bundle pacing(HBP),certain drawbacks including lead instability and dislodgements,steep learning curve and rapid battery depletion on many occasions prevented its widespread use for cardiac resynchronization therapy(CRT).Subsequently,CSP via left bundle branch-area pacing(LBBP)was developed in 2018,which over the last few years has shown efficacy comparable to BiVP-CRT in small observational studies.Further,its safety has also been well established and is largely free of the pitfalls of the HBP-CRT.In the recent metanalysis by Yasmin et al,comprising of 6 studies with 389 participants,LBBPCRT was superior to BiVP-CRT in terms of QRS duration,left ventricular ejection fraction,cardiac chamber dimensions,lead thresholds,and functional status amongst heart failure patients with left bundle branch block.However,there are important limitations of the study including the small overall numbers,inclusion of only a single small randomized controlled trial(RCT)and a small follow-up duration.Further,the entire study population analyzed was from China which makes generalizability a concern.Despite the concerns,the meta-analysis adds to the growing body of evidence demonstrating the efficacy of LBBP-CRT.At this stage,one must acknowledge that the fact that stil
基金supported by Projects of Hebei Provincial Administration of Traditional Chinese Medicine, No. 2014038, No. 2015145~~
文摘Objective： To observe the instant analgesic effect of Governor Vessel-regulating and collateral-unblocking acupuncture method in treating primary headache and to inherit and carry forward the academic achievements of Gao＇s acupuncture school in Yanzhao （Hebei Province） area. Methods： Eighty eligible primary headache patients were randomized into an observation group and a control group following their visiting sequence, 40 patients in each group. The observation group was intervened by Yanzhao Gao＇s Governor Vessel-regulating and collateral-unblocking acupuncture, and the control group was intervened by ordinary acupuncture method. The visual analogue scale （VAS） was used to evaluate the headache intensity before and after the first treatment session in the two groups, to compare the instant analgesic effect of the two acupuncture methods. Results： After the first treatment session, the VAS scores dropped significantly in both groups （both P〈0.05）. The change of VAS score after the initial treatment in the observation group was significantly different from that in the control group （P〈0.05）. The percentage of patients with headache completely vanished instantly after the first treatment was markedly higher in the observation group than that in the control group （P〈0.05）. Conclusion： The two acupuncture methods both can produce a significant instant analgesic effect in treating primary headache, while Yanzhao Gao＇s Governor Vessel-regulating and collateral-unblocking acupuncture method is superior to ordinary acupuncture method.
文摘BACKGROUND Fourth degree burns damage the full thickness of the skin and affect underlying tissues.Skin grafting after debridement is often used to cover the wounds of salvageable severe burns.A granulation wound can be formed by drilling the skull to the barrier layer to solve the problem of skull exposure.Low oxygen levels present at high altitudes aggravate ischemia and hypoxia which can negatively impact wound healing.The impaired healing in such cases can be ameliorated by hyperbaric oxygen therapy.CASE SUMMARY We describe a patient who presented with fourth degree burns to the left temporal and facial regions upon admission in December 2018.The periosteum of the skull and the deep fascia of the face were exposed.After the first stage of debridement and skin grafting,the temporal skin did not survive well.Granulation was induced by cranial drilling,and then a local flap was transferred to cover the wound.The left temporal and facial wounds were completely covered and the patient recovered well.CONCLUSION Skin grafting and flap transfer after early debridement to cover the wound and control infection were of great significance.In the later stages of the patient's treatment,survival of the skin graft and skin flap was observed.The second stage repair was performed to achieve successful skin grafting by cranial granulation.Granulation was formed by drilling the skull,and then the wound was closed,which is suitable for cases with skull exposure and wounds with poor blood supply.We consider that hyperbaric oxygen treatment and improving tissue oxygen supply were beneficial in this patient.
