The application of dams built upstream will change the input conditions, including water and sediment, of downstream fluvial system, and destroy previous dynamic quasi-equilibrium reached by channel streamflow, so ind...The application of dams built upstream will change the input conditions, including water and sediment, of downstream fluvial system, and destroy previous dynamic quasi-equilibrium reached by channel streamflow, so indispensable adjustments are necessary for downstream channel to adapt to the new water and sediment supply, leading the fluvial system to restore its previous equilibrium or reach a new equilibrium. Using about 50-year-long hydrological, sedimentary and cross-sectional data, temporal response processes of Toudaoguai cross-section located in the upper Yellow River to the operation of reservoirs built upstream are analyzed. The results show that the Toudaoguai cross-section change was influenced strongly by upstream reservoir operation and downstream channel bed armoring thereafter occurred gradually and extended to the reach below Sanhuhekou gauging station. Besides, median diameter of suspended sediment load experienced a three-stage change that is characterized by an increase at first, then a decrease and an increase again finally, which reflects the process of channel bed armoring that began at Qingtongxia reservoir and then gradually developed downstream to the reach below Sanhuhekou cross-section. Since the joint operation strategy of Longyangxia, Liujiaxia and Qingtongxia reservoirs was introduced in 1986, the three-stage change trend has become less evident than that in the time period between 1969 and 1986 when only Qingtongxia and Liujiaxia reservoirs were put into operation alone. In addition, since 1987, the extent of lateral migration and thalweg elevation change at Toudaoguai cross-section has reduced dramatically, cross-sectional profile and location tended to be stable, which is beneficial to the normal living for local people.展开更多
无线传感器网络中的错误测量数据会导致网络服务质量下降和能量浪费.提出了一种通过融合邻居节点的测量数据来实现故障检测的策略.主要做了以下3项工作:(1)提出了一种新颖的对邻居节点测量数据进行加权的方法;(2)提出了一种衡量测量数...无线传感器网络中的错误测量数据会导致网络服务质量下降和能量浪费.提出了一种通过融合邻居节点的测量数据来实现故障检测的策略.主要做了以下3项工作:(1)提出了一种新颖的对邻居节点测量数据进行加权的方法;(2)提出了一种衡量测量数据之间差距的方法;(3)提出了基于加权中值的故障诊断策略WMFDS(weighted median fault detection scheme),它同时适用于二进制决策和实数测量值.理论分析及仿真结果表明,即使节点发生故障的概率很高,提出的诊断策略也能得到很高的检测精度和较小的误判率,这表明在无线传感器网络故障检测中应用该方法具有很好的性能.展开更多
In order to overcome the phenomenon of image blur and edge loss in the process of collecting and transmitting medical image,a denoising method of medical image based on discrete wavelet transform(DWT)and modified medi...In order to overcome the phenomenon of image blur and edge loss in the process of collecting and transmitting medical image,a denoising method of medical image based on discrete wavelet transform(DWT)and modified median filter for medical image coupling denoising is proposed.The method is composed of four modules:image acquisition,image storage,image processing and image reconstruction.Image acquisition gets the medical image that contains Gaussian noise and impulse noise.Image storage includes the preservation of data and parameters of the original image and processed image.In the third module,the medical image is decomposed as four sub bands(LL,HL,LH,HH)by wavelet decomposition,where LL is low frequency,LH,HL,HH are respective for horizontal,vertical and in the diagonal line high frequency component.Using improved wavelet threshold to process high frequency coefficients and retain low frequency coefficients,the modified median filtering is performed on three high frequency sub bands after wavelet threshold processing.The last module is image reconstruction,which means getting the image after denoising by wavelet reconstruction.The advantage of this method is combining the advantages of median filter and wavelet to make the denoising effect better,not a simple combination of the two previous methods.With DWT and improved median filter coefficients coupling denoising,it is highly practical for high-precision medical images containing complex noises.The experimental results of proposed algorithm are compared with the results of median filter,wavelet transform,contourlet and DT-CWT,etc.According to visual evaluation index PSNR and SNR and Canny edge detection,in low noise images,PSNR and SNR increase by 10%–15%;in high noise images,PSNR and SNR increase by 2%–6%.The experimental results of the proposed algorithm achieved better acceptable results compared with other methods,which provides an important method for the diagnosis of medical condition.展开更多
In this study, rats were put into traumatic brain injury-induced coma and treated with median nerve electrical stimulation. We explored the wake-promoting effect, and possible mechanisms, of median nerve electrical st...In this study, rats were put into traumatic brain injury-induced coma and treated with median nerve electrical stimulation. We explored the wake-promoting effect, and possible mechanisms, of median nerve electrical stimulation. Electrical stimulation upregulated the expression levels of orexin-A and its receptor OX1R in the rat prefrontal cortex. Orexin-A expression gradually in-creased with increasing stimulation, while OX1R expression reached a peak at 12 hours and then decreased. In addition, after the OX1R antagonist, SB334867, was injected into the brain of rats after traumatic brain injury, fewer rats were restored to consciousness, and orexin-A and OXIR expression in the prefrontal cortex was downregulated. Our ifndings indicate that median nerve electrical stimulation induced an up-regulation of orexin-A and OX1R expression in the pre-frontal cortex of traumatic brain injury-induced coma rats, which may be a potential mechanism involved in the wake-promoting effects of median nerve electrical stimulation.展开更多
To understand the variations in vegetation and their correlation with climate factors in the upper catchments of the Yellow River, China, Normalized Difference Vegetation Index（NDVI） time series data from 2000 to 20...To understand the variations in vegetation and their correlation with climate factors in the upper catchments of the Yellow River, China, Normalized Difference Vegetation Index（NDVI） time series data from 2000 to 2010 were collected based on the MOD13Q1 product. The coefficient of variation, Theil–Sen median trend analysis and the Mann–Kendall test were combined to investigate the volatility characteristic and trend characteristic of the vegetation. Climate data sets were then used to analyze the correlation between variations in vegetation and climate change. In terms of the temporal variations, the vegetation in this study area improved slightly from 2000 to 2010, although the volatility characteristic was larger in 2000–2005 than in 2006–2010. In terms of the spatial variation, vegetation which is relatively stable and has a significantly increasing trend accounts for the largest part of the study area. Its spatial distribution is highly correlated with altitude, which ranges from about 2000 to 3000 m in this area. Highly fluctuating vegetation and vegetation which showed a significantly decreasing trend were mostly distributed around the reservoirs and in the reaches of the river with hydropower developments. Vegetation with a relatively stable and significantly decreasing trend and vegetation with a highly fluctuating and significantly increasing trend are widely dispersed. With respect to the response of vegetation to climate change, about 20–30% of the vegetation has a significant correlation with climatic factors and the correlations in most areas are positive： regions with precipitation as the key influencing factor account for more than 10% of the area; regions with temperature as the key influencing factor account for less than 10% of the area; and regions with precipitation and temperature as the key influencing factors together account for about 5% of the total area. More than 70% of the vegetation has an insignificant correlation with climatic factors.展开更多
[Objective] The aim of this study is to evaluate the safety and bacteriostasis of Yandureqing(AEE)and its microemulsion(AEE-ME).[Method]The acute toxicity was tested in mice by intragastric administration,and median l...[Objective] The aim of this study is to evaluate the safety and bacteriostasis of Yandureqing(AEE)and its microemulsion(AEE-ME).[Method]The acute toxicity was tested in mice by intragastric administration,and median lethal dose(LD50)as well as its 95% confidence interval was calculated by modified Karber method;the bacteriostasis was investigated by cylinder plate method.[Result]LD50 of AEE in mice was 10.937 g/kg with the 95% confidence interval of 9.309-12.850 g/kg;and LD50 of AEE-ME in mice was 5.357 g/kg with the 95% confidence interval of 4.388-6.566 g/kg.The MICs of AEE to Escherichia coli O149 from swine,Staphylococcus aureus,Salmonella pullorum and Streptococcus agalactiae were 10.00,20.00,20.00 and 10.00 mg/ml,respectively;while the MICs of AEE-ME to the 4 kinds of bacteria mentioned above were 5.00,10.00,5.00 and 5.00 mg/ml in turn,and that to Pseudomonas aeruginosa is 20.00 mg/ml.[Conclusion]AEE is an actually nontoxic drug and AEE-ME belongs to the low toxic preparation.AEE and AEE-ME have obvious bacteriostasis,in which AEE-ME is superior to AEE.展开更多
Electrical stimulation of the median nerve is a noninvasive technique that facilitates awakening from coma. In rats with traumatic brain injury-induced coma, median nerve stimulation markedly enhances prefrontal corte...Electrical stimulation of the median nerve is a noninvasive technique that facilitates awakening from coma. In rats with traumatic brain injury-induced coma, median nerve stimulation markedly enhances prefrontal cortex expression of orexin-A and its receptor, orexin receptor 1. To further understand the mechanism underlying wakefulness mediated by electrical stimulation of the median nerve, we evaluated its effects on the expression of the N-methyl-D-aspartate receptor subunit NR1 in the prefrontal cortex in rat models of traumatic brain injury-induced coma, using immunohistochemistry and western blot assays. In rats with traumatic brain injury, NR1 expression increased with time after injury. Rats that underwent electrical stimulation of the median nerve（30 Hz, 0.5 ms, 1.0 m A for 15 minutes） showed elevated NR1 expression and greater recovery of consciousness than those without stimulation. These effects were reduced by intracerebroventricular injection of the orexin receptor 1 antagonist SB334867. Our results indicate that electrical stimulation of the median nerve promotes recovery from traumatic brain injury-induced coma by increasing prefrontal cortex NR1 expression via an orexin-A-mediated pathway.展开更多
基金National Natural Science Foundation of China, No.40771031 Thanks are expressed to the Yellow River Conservancy Commission and International Network on Erosion and Sedimentation for the permission of access to hydrometric data. We are also grateful to Dr. Wang Xiujie from Tianjin University for his generous help.
文摘The application of dams built upstream will change the input conditions, including water and sediment, of downstream fluvial system, and destroy previous dynamic quasi-equilibrium reached by channel streamflow, so indispensable adjustments are necessary for downstream channel to adapt to the new water and sediment supply, leading the fluvial system to restore its previous equilibrium or reach a new equilibrium. Using about 50-year-long hydrological, sedimentary and cross-sectional data, temporal response processes of Toudaoguai cross-section located in the upper Yellow River to the operation of reservoirs built upstream are analyzed. The results show that the Toudaoguai cross-section change was influenced strongly by upstream reservoir operation and downstream channel bed armoring thereafter occurred gradually and extended to the reach below Sanhuhekou gauging station. Besides, median diameter of suspended sediment load experienced a three-stage change that is characterized by an increase at first, then a decrease and an increase again finally, which reflects the process of channel bed armoring that began at Qingtongxia reservoir and then gradually developed downstream to the reach below Sanhuhekou cross-section. Since the joint operation strategy of Longyangxia, Liujiaxia and Qingtongxia reservoirs was introduced in 1986, the three-stage change trend has become less evident than that in the time period between 1969 and 1986 when only Qingtongxia and Liujiaxia reservoirs were put into operation alone. In addition, since 1987, the extent of lateral migration and thalweg elevation change at Toudaoguai cross-section has reduced dramatically, cross-sectional profile and location tended to be stable, which is beneficial to the normal living for local people.
基金Supported by the National Natural Science Foundation of China under Grant No.60633060(国家自然科学基金)the National High-Tech Research and Development Plan of China under Grant No.2006AA01Z223(国家高技术研究发展计划(863))the National Grand Fundamental Research973Program of China under Grant No.2005CB321604(国家重点基础研究发展规划(973))
文摘无线传感器网络中的错误测量数据会导致网络服务质量下降和能量浪费.提出了一种通过融合邻居节点的测量数据来实现故障检测的策略.主要做了以下3项工作:(1)提出了一种新颖的对邻居节点测量数据进行加权的方法;(2)提出了一种衡量测量数据之间差距的方法;(3)提出了基于加权中值的故障诊断策略WMFDS(weighted median fault detection scheme),它同时适用于二进制决策和实数测量值.理论分析及仿真结果表明,即使节点发生故障的概率很高,提出的诊断策略也能得到很高的检测精度和较小的误判率,这表明在无线传感器网络故障检测中应用该方法具有很好的性能.
基金Project(2016JJ4074)supported by the Natural Science Foundation of Hunan Province,ChinaProject(14C0920)supported by the Hunan Provincial Education Department,ChinaProject(61771191)supported by the National Natural Science Foundation of China
文摘In order to overcome the phenomenon of image blur and edge loss in the process of collecting and transmitting medical image,a denoising method of medical image based on discrete wavelet transform(DWT)and modified median filter for medical image coupling denoising is proposed.The method is composed of four modules:image acquisition,image storage,image processing and image reconstruction.Image acquisition gets the medical image that contains Gaussian noise and impulse noise.Image storage includes the preservation of data and parameters of the original image and processed image.In the third module,the medical image is decomposed as four sub bands(LL,HL,LH,HH)by wavelet decomposition,where LL is low frequency,LH,HL,HH are respective for horizontal,vertical and in the diagonal line high frequency component.Using improved wavelet threshold to process high frequency coefficients and retain low frequency coefficients,the modified median filtering is performed on three high frequency sub bands after wavelet threshold processing.The last module is image reconstruction,which means getting the image after denoising by wavelet reconstruction.The advantage of this method is combining the advantages of median filter and wavelet to make the denoising effect better,not a simple combination of the two previous methods.With DWT and improved median filter coefficients coupling denoising,it is highly practical for high-precision medical images containing complex noises.The experimental results of proposed algorithm are compared with the results of median filter,wavelet transform,contourlet and DT-CWT,etc.According to visual evaluation index PSNR and SNR and Canny edge detection,in low noise images,PSNR and SNR increase by 10%–15%;in high noise images,PSNR and SNR increase by 2%–6%.The experimental results of the proposed algorithm achieved better acceptable results compared with other methods,which provides an important method for the diagnosis of medical condition.
基金funded by grants from the National Natural Science Foundation of China,No.81260295the Natural Science Foundation of Jiangxi Province of China,No.20132BAB205063
文摘In this study, rats were put into traumatic brain injury-induced coma and treated with median nerve electrical stimulation. We explored the wake-promoting effect, and possible mechanisms, of median nerve electrical stimulation. Electrical stimulation upregulated the expression levels of orexin-A and its receptor OX1R in the rat prefrontal cortex. Orexin-A expression gradually in-creased with increasing stimulation, while OX1R expression reached a peak at 12 hours and then decreased. In addition, after the OX1R antagonist, SB334867, was injected into the brain of rats after traumatic brain injury, fewer rats were restored to consciousness, and orexin-A and OXIR expression in the prefrontal cortex was downregulated. Our ifndings indicate that median nerve electrical stimulation induced an up-regulation of orexin-A and OX1R expression in the pre-frontal cortex of traumatic brain injury-induced coma rats, which may be a potential mechanism involved in the wake-promoting effects of median nerve electrical stimulation.
基金National Natural Science Foundation of China,No.41171318 National Key Technology Support Program,No.2012BAH32B03+1 种基金No.2012BAH33B05 The Remote Sensing Investigation and Assessment Project for Decade-Change of the National Ecological Environment（2000–2010）
文摘To understand the variations in vegetation and their correlation with climate factors in the upper catchments of the Yellow River, China, Normalized Difference Vegetation Index（NDVI） time series data from 2000 to 2010 were collected based on the MOD13Q1 product. The coefficient of variation, Theil–Sen median trend analysis and the Mann–Kendall test were combined to investigate the volatility characteristic and trend characteristic of the vegetation. Climate data sets were then used to analyze the correlation between variations in vegetation and climate change. In terms of the temporal variations, the vegetation in this study area improved slightly from 2000 to 2010, although the volatility characteristic was larger in 2000–2005 than in 2006–2010. In terms of the spatial variation, vegetation which is relatively stable and has a significantly increasing trend accounts for the largest part of the study area. Its spatial distribution is highly correlated with altitude, which ranges from about 2000 to 3000 m in this area. Highly fluctuating vegetation and vegetation which showed a significantly decreasing trend were mostly distributed around the reservoirs and in the reaches of the river with hydropower developments. Vegetation with a relatively stable and significantly decreasing trend and vegetation with a highly fluctuating and significantly increasing trend are widely dispersed. With respect to the response of vegetation to climate change, about 20–30% of the vegetation has a significant correlation with climatic factors and the correlations in most areas are positive： regions with precipitation as the key influencing factor account for more than 10% of the area; regions with temperature as the key influencing factor account for less than 10% of the area; and regions with precipitation and temperature as the key influencing factors together account for about 5% of the total area. More than 70% of the vegetation has an insignificant correlation with climatic factors.
基金Supported by Specific Program Funded by Basic Scientific Research Operating Expenses of Central Public Scientific Research Institutes(BRF060403)Key Project of Scientific and Technical Supporting Pro-grams of Gansu Province(0804NKCA074)~~
文摘[Objective] The aim of this study is to evaluate the safety and bacteriostasis of Yandureqing(AEE)and its microemulsion(AEE-ME).[Method]The acute toxicity was tested in mice by intragastric administration,and median lethal dose(LD50)as well as its 95% confidence interval was calculated by modified Karber method;the bacteriostasis was investigated by cylinder plate method.[Result]LD50 of AEE in mice was 10.937 g/kg with the 95% confidence interval of 9.309-12.850 g/kg;and LD50 of AEE-ME in mice was 5.357 g/kg with the 95% confidence interval of 4.388-6.566 g/kg.The MICs of AEE to Escherichia coli O149 from swine,Staphylococcus aureus,Salmonella pullorum and Streptococcus agalactiae were 10.00,20.00,20.00 and 10.00 mg/ml,respectively;while the MICs of AEE-ME to the 4 kinds of bacteria mentioned above were 5.00,10.00,5.00 and 5.00 mg/ml in turn,and that to Pseudomonas aeruginosa is 20.00 mg/ml.[Conclusion]AEE is an actually nontoxic drug and AEE-ME belongs to the low toxic preparation.AEE and AEE-ME have obvious bacteriostasis,in which AEE-ME is superior to AEE.
基金supported by the National Natural Science Foundation of China,No.81260295the Natural Science Foundation of Jiangxi Province of China,No.20132BAB205063
文摘Electrical stimulation of the median nerve is a noninvasive technique that facilitates awakening from coma. In rats with traumatic brain injury-induced coma, median nerve stimulation markedly enhances prefrontal cortex expression of orexin-A and its receptor, orexin receptor 1. To further understand the mechanism underlying wakefulness mediated by electrical stimulation of the median nerve, we evaluated its effects on the expression of the N-methyl-D-aspartate receptor subunit NR1 in the prefrontal cortex in rat models of traumatic brain injury-induced coma, using immunohistochemistry and western blot assays. In rats with traumatic brain injury, NR1 expression increased with time after injury. Rats that underwent electrical stimulation of the median nerve（30 Hz, 0.5 ms, 1.0 m A for 15 minutes） showed elevated NR1 expression and greater recovery of consciousness than those without stimulation. These effects were reduced by intracerebroventricular injection of the orexin receptor 1 antagonist SB334867. Our results indicate that electrical stimulation of the median nerve promotes recovery from traumatic brain injury-induced coma by increasing prefrontal cortex NR1 expression via an orexin-A-mediated pathway.
