A model of the solution space for all the sensor mechanisms based on the Stewart platform is established, which is a novel and useful tool for investigation of the optimal sensor design. A kind of performance evaluati...A model of the solution space for all the sensor mechanisms based on the Stewart platform is established, which is a novel and useful tool for investigation of the optimal sensor design. A kind of performance evaluation atlases are plotted within the model of the solution space, which clearly show relationships between the condition number of Jacobjan matrix and parameters of all the sensor mechanisms. By using the performance atlases, an optimal design for the sensor mechanism can be achieved. Because the elastic joints are proposed for replacing the spherical joints, the Stewart platform based sensor can be designed as small as possible.展开更多
Summary： With dwindling number of new antibiotics and inappropriate use of antibiotics, the emergence and spread of antibiotics resistance occurs commonly in healthcare institutions worldwide. In China, antibiotics a...Summary： With dwindling number of new antibiotics and inappropriate use of antibiotics, the emergence and spread of antibiotics resistance occurs commonly in healthcare institutions worldwide. In China, antibiotics are commonly overprescribed and misused. This study is to assess the effect of the nationwide special campaign on antibiotic stewardship program （ASP） at specialized hospitals in China by investigating prescription information from 2011 to 2012. Data on the hospital consumption and prescription of systemic antibiotics were obtained from four specialized hospitals, including maternity, children＇s, stomatological and cancer hospitals. Systematic random sampling was used to select outpatient prescriptions and inpatient cases. A total of 105 specialized hospitals in 2011 and 121 specialized hospitals in 2012 were analysed. The defined daily doses （DDDs） per 100 inpatient days, the percentage of antibiotic use in outpatient prescriptions, and the percentage of antibiotic use in inpatient eases were used as measurements of antibiotic use. The overall antibiotic use density in the selected hospitals decreased between 2011 and 2012 from 39.37 to 26.54 DDD/100 inpatient days （P〈0.001）. The percentage of antibiotic use in outpatient prescriptions （range： 24.12%-18.71%, P=0.109） and inpatient cases （64.85%-60.10%, P=-0.006） also decreased within the two years. Significant changes were observed among regions and different hospitals within the two years. And antibiotic consumption was correlated with the type and size of specialized hospital in 2012, but not with the regions. This analysis of antibiotic consumption of specialized hospitals allows relevant comparisons for benchmarking and shows that national ASP has improved antibiotic rational use in China. The data will assist policymakers in formulating effective strategies to decrease antibiotic overuse and identify areas that require further work.展开更多
The James Webb Space Telescope(JWST),which cleared a slew of complex technical hurdles and became operational over 2021,has awed and surprised astronomers(Figs.1 and 2).“We are able to see things we had not imagined ...The James Webb Space Telescope(JWST),which cleared a slew of complex technical hurdles and became operational over 2021,has awed and surprised astronomers(Figs.1 and 2).“We are able to see things we had not imagined we would see,”said Christopher Willmer,associate research professor at the University of Arizona Steward Observatory in Tucson,AZ,USA,who has worked on the project since 2007.展开更多
In order to achieve attitude control of the six degrees of freedom steward dynamic platform, as well as the real time simulation cockpit attitude, Washout Filtering method was adopted in this paper as the simulation a...In order to achieve attitude control of the six degrees of freedom steward dynamic platform, as well as the real time simulation cockpit attitude, Washout Filtering method was adopted in this paper as the simulation algorithm to derive Washout Fiher high-pass, low-pass filter transfer functions into a differential equation algorithm and longitudinal acceleration tilt strategy, pitching strategies etc. Experimental examples are used to verify correctness of the algorithm.展开更多
The FAIR Guidelines attempts to make digital data Findable, Accessible, Interoperable, and Reusable(FAIR). To prepare FAIR data, a new data science discipline known as data stewardship is emerging and, as the FAIR Gui...The FAIR Guidelines attempts to make digital data Findable, Accessible, Interoperable, and Reusable(FAIR). To prepare FAIR data, a new data science discipline known as data stewardship is emerging and, as the FAIR Guidelines gain more acceptance, an increase in the demand for data stewards is expected. Consequently, there is a need to develop curricula to foster professional skills in data stewardship through effective knowledge communication. There have been a number of initiatives aimed at bridging the gap in FAIR data management training through both formal and informal programmes. This article describes the experience of developing a digital initiative for FAIR data management training under the Digital Innovations and Skills Hub(DISH) project. The FAIR Data Management course offers 6 short on-demand certificate modules over 12 weeks. The modules are divided into two sets: FAIR data and data science. The core subjects cover elementary topics in data science, regulatory frameworks, FAIR data management, intermediate to advanced topics in FAIR Data Point installation, and FAIR data in the management of healthcare and semantic data. Each week, participants are required to devote 7–8 hours of self-study to the modules, based on the resources provided. Once they have satisfied all requirements, students are certified as FAIR data scientists and qualified to serve as both FAIR data stewards and analysts. It is expected that in-depth and focused curricula development with diverse participants will build a core of FAIR data scientists for Data Competence Centres and encourage the rapid adoption of the FAIR Guidelines for research and development.展开更多
The totipotency of higher plant somatic cells was first demonstrated by Steward on carrot. Since then, tissue culture has been widely practised from which the totipotency of many plant somatic cells has been observed....The totipotency of higher plant somatic cells was first demonstrated by Steward on carrot. Since then, tissue culture has been widely practised from which the totipotency of many plant somatic cells has been observed. The key substance in inducing totipotency seems to be kinetin and cytokinin. Similar work was reported on the Laminaria sporophytes by Saga et al. with limited success. In our laboratory, we used the sporophytes of Laminaria japonica and Undaria pinnatifida to test the totipotency of the somatic cells with a newly synthetic hormone C-751.展开更多
文摘A model of the solution space for all the sensor mechanisms based on the Stewart platform is established, which is a novel and useful tool for investigation of the optimal sensor design. A kind of performance evaluation atlases are plotted within the model of the solution space, which clearly show relationships between the condition number of Jacobjan matrix and parameters of all the sensor mechanisms. By using the performance atlases, an optimal design for the sensor mechanism can be achieved. Because the elastic joints are proposed for replacing the spherical joints, the Stewart platform based sensor can be designed as small as possible.
基金supported by grants from the General Program of National Natural Science Foundation of China(No.71073062)Major Project in Philosophy and Social Science of Ministry of Education in China(No.10JZD0027)
文摘Summary： With dwindling number of new antibiotics and inappropriate use of antibiotics, the emergence and spread of antibiotics resistance occurs commonly in healthcare institutions worldwide. In China, antibiotics are commonly overprescribed and misused. This study is to assess the effect of the nationwide special campaign on antibiotic stewardship program （ASP） at specialized hospitals in China by investigating prescription information from 2011 to 2012. Data on the hospital consumption and prescription of systemic antibiotics were obtained from four specialized hospitals, including maternity, children＇s, stomatological and cancer hospitals. Systematic random sampling was used to select outpatient prescriptions and inpatient cases. A total of 105 specialized hospitals in 2011 and 121 specialized hospitals in 2012 were analysed. The defined daily doses （DDDs） per 100 inpatient days, the percentage of antibiotic use in outpatient prescriptions, and the percentage of antibiotic use in inpatient eases were used as measurements of antibiotic use. The overall antibiotic use density in the selected hospitals decreased between 2011 and 2012 from 39.37 to 26.54 DDD/100 inpatient days （P〈0.001）. The percentage of antibiotic use in outpatient prescriptions （range： 24.12%-18.71%, P=0.109） and inpatient cases （64.85%-60.10%, P=-0.006） also decreased within the two years. Significant changes were observed among regions and different hospitals within the two years. And antibiotic consumption was correlated with the type and size of specialized hospital in 2012, but not with the regions. This analysis of antibiotic consumption of specialized hospitals allows relevant comparisons for benchmarking and shows that national ASP has improved antibiotic rational use in China. The data will assist policymakers in formulating effective strategies to decrease antibiotic overuse and identify areas that require further work.
文摘The James Webb Space Telescope(JWST),which cleared a slew of complex technical hurdles and became operational over 2021,has awed and surprised astronomers(Figs.1 and 2).“We are able to see things we had not imagined we would see,”said Christopher Willmer,associate research professor at the University of Arizona Steward Observatory in Tucson,AZ,USA,who has worked on the project since 2007.
文摘In order to achieve attitude control of the six degrees of freedom steward dynamic platform, as well as the real time simulation cockpit attitude, Washout Filtering method was adopted in this paper as the simulation algorithm to derive Washout Fiher high-pass, low-pass filter transfer functions into a differential equation algorithm and longitudinal acceleration tilt strategy, pitching strategies etc. Experimental examples are used to verify correctness of the algorithm.
基金VODAN-Africathe Philips Foundation+2 种基金the Dutch Development Bank FMOCORDAIDthe GO FAIR Foundation for supporting this research
文摘The FAIR Guidelines attempts to make digital data Findable, Accessible, Interoperable, and Reusable(FAIR). To prepare FAIR data, a new data science discipline known as data stewardship is emerging and, as the FAIR Guidelines gain more acceptance, an increase in the demand for data stewards is expected. Consequently, there is a need to develop curricula to foster professional skills in data stewardship through effective knowledge communication. There have been a number of initiatives aimed at bridging the gap in FAIR data management training through both formal and informal programmes. This article describes the experience of developing a digital initiative for FAIR data management training under the Digital Innovations and Skills Hub(DISH) project. The FAIR Data Management course offers 6 short on-demand certificate modules over 12 weeks. The modules are divided into two sets: FAIR data and data science. The core subjects cover elementary topics in data science, regulatory frameworks, FAIR data management, intermediate to advanced topics in FAIR Data Point installation, and FAIR data in the management of healthcare and semantic data. Each week, participants are required to devote 7–8 hours of self-study to the modules, based on the resources provided. Once they have satisfied all requirements, students are certified as FAIR data scientists and qualified to serve as both FAIR data stewards and analysts. It is expected that in-depth and focused curricula development with diverse participants will build a core of FAIR data scientists for Data Competence Centres and encourage the rapid adoption of the FAIR Guidelines for research and development.
文摘The totipotency of higher plant somatic cells was first demonstrated by Steward on carrot. Since then, tissue culture has been widely practised from which the totipotency of many plant somatic cells has been observed. The key substance in inducing totipotency seems to be kinetin and cytokinin. Similar work was reported on the Laminaria sporophytes by Saga et al. with limited success. In our laboratory, we used the sporophytes of Laminaria japonica and Undaria pinnatifida to test the totipotency of the somatic cells with a newly synthetic hormone C-751.
