OBJECTIVES: To analyze the characteristics of early hepatocellular carcinoma by using multi-phase helical CT and assess the value of this method. METHODS: Multi-phase helical CT findings were reviewed double-blindly b...OBJECTIVES: To analyze the characteristics of early hepatocellular carcinoma by using multi-phase helical CT and assess the value of this method. METHODS: Multi-phase helical CT findings were reviewed double-blindly by radiologists. RESULTS: Altogether 24 lesions were found in 21 patients. In plain CT, the lesions were seen as hypodense or isodense areas. After contrast enhancement, 87.5% of the lesions showed regular or irregular hyperdense enhancement, whereas 12.5% demonstrated tumor vessels in arterial phase, which became hypodensed or isodensed nodules in portal phase or the hypodensed in delayed phase. The prevalence of density changes showed a hypo-hyper-hypo and hypo-hypo pattern. CONCLUSIONS: Multi-phase helical CT could reflect the blood supply of early hepatocelluar carcinoma, and is also convenient for the differential diagnosis of hepatic cavernous angioma, metastatic tumor, hepatic nodulous hyperplasia, and hepatic inflammatory granuloma.展开更多
The wavefront shaping based technique has been introduced to detect the edges of amplitude objects through complex media,but the extraction of the boundary information of invisible phase objects through complex media ...The wavefront shaping based technique has been introduced to detect the edges of amplitude objects through complex media,but the extraction of the boundary information of invisible phase objects through complex media has not been demonstrated yet.Here,we present a phase contrast imaging technique to overcome the scattering,aiming to achieve the edge detection of the phase object through the complex media.An operator based on the experimentally measured transmission matrix is obtained by numerically adding a spiral phase in the Fourier domain.With the inverse of the filtered transmission matrix,we can directly reconstruct the edge enhanced images for both amplitude object and phase object beyond scattering.Experimentally,both digital and real objects are imaged,and the results verify that isotropic edge detection can be achieved with our technique.Our work could benefit the detection of invisible phase objects through complex media.展开更多
A patient with insulinoma diagnosed by clinical features and localized preoperatively using a combination of contrast-enhanced ultrasonography （CEUS）, dual phase contrast enhanced spiral computed tomography （DPSCT...A patient with insulinoma diagnosed by clinical features and localized preoperatively using a combination of contrast-enhanced ultrasonography （CEUS）, dual phase contrast enhanced spiral computed tomography （DPSCT） and arterial stimulation and venous sampling （ASVS） was reported. A 37-year-old man was admitted to our hospital because of hypoglycemic attacks, palpitations, and muscular weakness. Fajans＇ ratio reported to be an index for insulinoma was positive. Transabdominal computed tomography and ultrasonography failed to detect any abnormalities. CEUS showed a small low echoic lesion in the pancreatic body with blood flow and the early arterial phase of DPSCT revealed a small strengthening focus, which mimicked a pancreatic tumor in the pancreatic body. ASVS showed that the insulin levels in the hepatic vein were extremely increased by calcium injection to the gastroduodenal artery. An open intra-abdominal operation was performed and an insulinoma was confirmed in the pancreatic body. Enucleation of tumor was undertaken and histopathological examination showed an adenoma, insulin expression was positive in immunofluorescence staining.Symptomatic hypoglycemia never happened even without glucose infusion since the operation. His blood glucose level improved to within the normal range.展开更多
文摘OBJECTIVES: To analyze the characteristics of early hepatocellular carcinoma by using multi-phase helical CT and assess the value of this method. METHODS: Multi-phase helical CT findings were reviewed double-blindly by radiologists. RESULTS: Altogether 24 lesions were found in 21 patients. In plain CT, the lesions were seen as hypodense or isodense areas. After contrast enhancement, 87.5% of the lesions showed regular or irregular hyperdense enhancement, whereas 12.5% demonstrated tumor vessels in arterial phase, which became hypodensed or isodensed nodules in portal phase or the hypodensed in delayed phase. The prevalence of density changes showed a hypo-hyper-hypo and hypo-hypo pattern. CONCLUSIONS: Multi-phase helical CT could reflect the blood supply of early hepatocelluar carcinoma, and is also convenient for the differential diagnosis of hepatic cavernous angioma, metastatic tumor, hepatic nodulous hyperplasia, and hepatic inflammatory granuloma.
基金This work was supported by the National Key Research and Development Program of China(No.2019YFA0705000)the National Natural Science Foundation of China(NSFC)(Nos.12004219,120742251,2192254,91750201,and 11974218)+1 种基金the Innovation Group of Jinan(No.2018GXRC010)the Local Science and Technology Development Project of the Central Government(No.YDZX20203700001766).
文摘The wavefront shaping based technique has been introduced to detect the edges of amplitude objects through complex media,but the extraction of the boundary information of invisible phase objects through complex media has not been demonstrated yet.Here,we present a phase contrast imaging technique to overcome the scattering,aiming to achieve the edge detection of the phase object through the complex media.An operator based on the experimentally measured transmission matrix is obtained by numerically adding a spiral phase in the Fourier domain.With the inverse of the filtered transmission matrix,we can directly reconstruct the edge enhanced images for both amplitude object and phase object beyond scattering.Experimentally,both digital and real objects are imaged,and the results verify that isotropic edge detection can be achieved with our technique.Our work could benefit the detection of invisible phase objects through complex media.
文摘A patient with insulinoma diagnosed by clinical features and localized preoperatively using a combination of contrast-enhanced ultrasonography （CEUS）, dual phase contrast enhanced spiral computed tomography （DPSCT） and arterial stimulation and venous sampling （ASVS） was reported. A 37-year-old man was admitted to our hospital because of hypoglycemic attacks, palpitations, and muscular weakness. Fajans＇ ratio reported to be an index for insulinoma was positive. Transabdominal computed tomography and ultrasonography failed to detect any abnormalities. CEUS showed a small low echoic lesion in the pancreatic body with blood flow and the early arterial phase of DPSCT revealed a small strengthening focus, which mimicked a pancreatic tumor in the pancreatic body. ASVS showed that the insulin levels in the hepatic vein were extremely increased by calcium injection to the gastroduodenal artery. An open intra-abdominal operation was performed and an insulinoma was confirmed in the pancreatic body. Enucleation of tumor was undertaken and histopathological examination showed an adenoma, insulin expression was positive in immunofluorescence staining.Symptomatic hypoglycemia never happened even without glucose infusion since the operation. His blood glucose level improved to within the normal range.
