Compared with traditional solid-state drives(SSDs),open-channel SSDs(OCSSDs)expose their internal physical layout and provide a host-based flash translation layer(FTL)that allows host-side software to control the inte...Compared with traditional solid-state drives(SSDs),open-channel SSDs(OCSSDs)expose their internal physical layout and provide a host-based flash translation layer(FTL)that allows host-side software to control the internal operations such as garbage collection(GC)and input/output(I/O)scheduling.In this paper,we comprehensively survey research works built on OCSSDs in recent years.We show how they leverage the features of OCSSDs to achieve high throughput,low latency,long lifetime,strong performance isolation,and high resource utilization.We categorize these efforts into five groups based on their optimization methods:adaptive interface customizing,rich FTL co-designing,internal parallelism exploiting,rational I/O scheduling,and efficient GC processing.We discuss the strengths and weaknesses of these efforts and find that almost all these efforts face a dilemma between performance effectiveness and management complexity.We hope that this survey can provide fundamental knowledge to researchers who want to enter this field and further inspire new ideas for the development of OCSSDs.展开更多
AIM: To investigate the effects of dextrans of various molecular weights (Mw) during a 12 h cold storage time-course on energetics, histology and mucosal infiltration of fluorescein isothiocyanate (FITC)-dextran. METH...AIM: To investigate the effects of dextrans of various molecular weights (Mw) during a 12 h cold storage time-course on energetics, histology and mucosal infiltration of fluorescein isothiocyanate (FITC)-dextran. METHODS: Rodent intestines were isolated and received a standard University of Wisconsin vascular flush followed by intraluminal administration of a nutrientrich preservation solution containing dextrans of varying Mw: Group D1, 73 kdal; Group D2, 276 kdal; Group D3, 534 kdal; Group D4, 1185 kdal; Group D5, 2400 kdal. RESULTS: Using FITC-labeled dextrans, fluorescent micrographs demonstrated varying degrees of mucosal infiltration; lower Mw (groups D1-D3: 73-534 kdal) dextrans penetrated the mucosa as early as 2 h, whereas the largest dextran (D5: 2400 kdal) remained captive within the lumen and exhibited no permeability even after 12 h. After 12 h, median injury grades ranged from 6.5 to 7.5 in groups D1-D4 (73-1185 kdal) representing injury of the regenerative cryptal regions and submucosa; this was in contrast to group D5 (2400 kdal) which exhibited villus denudation (with intact crypts) corresponding to a median injury grade of 4 (P < 0.05). Analysis of tissue energetics reflected a strong positive correlation between Mw and adenosine triphosphate (r 2 = 0.809), total adenylates (r 2 = 0.865) and energy charge (r 2 = 0.667).CONCLUSION: Our data indicate that dextrans of Mw > 2400 kdal act as true impermeant agents during 12 h ischemic storage when incorporated into an intraluminal preservation solution.展开更多
This study was carried out to determine the thermo-physical properties of rubber seed in the moisture range of 9.1%to 14.8%(w.b.).The length,width,thickness,measured surface area,bulk density and true density increase...This study was carried out to determine the thermo-physical properties of rubber seed in the moisture range of 9.1%to 14.8%(w.b.).The length,width,thickness,measured surface area,bulk density and true density increased with increasing moisture content with high coefficients of determination(significant at p<0.05).Their optimum values at 14.8%moisture content were 17.00 mm,11.94 mm,8.26 mm,285.20 mm^(2),295.00 kg/m^(3) and 470.67 kg/m^(3),respectively.The angle of repose increased as moisture content increased with low coefficient of determination and has optimum value of 28.81°at 14.8%moisture content.The specific heat capacity and thermal conductivity decreased linearly while thermal diffusivity increased exponentially with an increase in moisture content(significant at p<0.05).The optimum values of specific heat capacity,thermal conductivity and diffusivity at 14.8%moisture content were 55.84 kJ/(kg.K),0.032 W/(m.K)and 1.93×10^(-9) m^(2)/s,respectively.The results are essential in the design of storage structure for rubber seed.展开更多
基金Project supported by the National Natural Science Foundation of China(No.62025203)。
文摘Compared with traditional solid-state drives(SSDs),open-channel SSDs(OCSSDs)expose their internal physical layout and provide a host-based flash translation layer(FTL)that allows host-side software to control the internal operations such as garbage collection(GC)and input/output(I/O)scheduling.In this paper,we comprehensively survey research works built on OCSSDs in recent years.We show how they leverage the features of OCSSDs to achieve high throughput,low latency,long lifetime,strong performance isolation,and high resource utilization.We categorize these efforts into five groups based on their optimization methods:adaptive interface customizing,rich FTL co-designing,internal parallelism exploiting,rational I/O scheduling,and efficient GC processing.We discuss the strengths and weaknesses of these efforts and find that almost all these efforts face a dilemma between performance effectiveness and management complexity.We hope that this survey can provide fundamental knowledge to researchers who want to enter this field and further inspire new ideas for the development of OCSSDs.
基金Supported by Operating funds awarded by the Canadian Institutes of Health Research(to Churchill TA)salary award from Alberta Heritage Foundation for Medical Research(to Kokotilo MS)
文摘AIM: To investigate the effects of dextrans of various molecular weights (Mw) during a 12 h cold storage time-course on energetics, histology and mucosal infiltration of fluorescein isothiocyanate (FITC)-dextran. METHODS: Rodent intestines were isolated and received a standard University of Wisconsin vascular flush followed by intraluminal administration of a nutrientrich preservation solution containing dextrans of varying Mw: Group D1, 73 kdal; Group D2, 276 kdal; Group D3, 534 kdal; Group D4, 1185 kdal; Group D5, 2400 kdal. RESULTS: Using FITC-labeled dextrans, fluorescent micrographs demonstrated varying degrees of mucosal infiltration; lower Mw (groups D1-D3: 73-534 kdal) dextrans penetrated the mucosa as early as 2 h, whereas the largest dextran (D5: 2400 kdal) remained captive within the lumen and exhibited no permeability even after 12 h. After 12 h, median injury grades ranged from 6.5 to 7.5 in groups D1-D4 (73-1185 kdal) representing injury of the regenerative cryptal regions and submucosa; this was in contrast to group D5 (2400 kdal) which exhibited villus denudation (with intact crypts) corresponding to a median injury grade of 4 (P < 0.05). Analysis of tissue energetics reflected a strong positive correlation between Mw and adenosine triphosphate (r 2 = 0.809), total adenylates (r 2 = 0.865) and energy charge (r 2 = 0.667).CONCLUSION: Our data indicate that dextrans of Mw > 2400 kdal act as true impermeant agents during 12 h ischemic storage when incorporated into an intraluminal preservation solution.
文摘This study was carried out to determine the thermo-physical properties of rubber seed in the moisture range of 9.1%to 14.8%(w.b.).The length,width,thickness,measured surface area,bulk density and true density increased with increasing moisture content with high coefficients of determination(significant at p<0.05).Their optimum values at 14.8%moisture content were 17.00 mm,11.94 mm,8.26 mm,285.20 mm^(2),295.00 kg/m^(3) and 470.67 kg/m^(3),respectively.The angle of repose increased as moisture content increased with low coefficient of determination and has optimum value of 28.81°at 14.8%moisture content.The specific heat capacity and thermal conductivity decreased linearly while thermal diffusivity increased exponentially with an increase in moisture content(significant at p<0.05).The optimum values of specific heat capacity,thermal conductivity and diffusivity at 14.8%moisture content were 55.84 kJ/(kg.K),0.032 W/(m.K)and 1.93×10^(-9) m^(2)/s,respectively.The results are essential in the design of storage structure for rubber seed.
