目的:探讨术前不同时间口服磷酸钠盐溶液进行肠道准备时对患者夜间睡眠质量的影响。方法:选取2014年7月至2015年10月广西壮族自治区人民医院收治的选择术前需要肠道准备的择期手术患者360例,随机分为观察组和对照组,每组180例,均用磷酸...目的:探讨术前不同时间口服磷酸钠盐溶液进行肠道准备时对患者夜间睡眠质量的影响。方法:选取2014年7月至2015年10月广西壮族自治区人民医院收治的选择术前需要肠道准备的择期手术患者360例,随机分为观察组和对照组,每组180例,均用磷酸钠盐口服溶液45 m L加温开水250 m L后服用,进行肠道准备,观察组术前1 d 16:00服用;对照组术前1d 19:00服用。应用国际上常用的Athens失眠量表评价2组患者手术前晚睡眠质量情况。结果:观察组Athens评分显著低于对照组,观察组当晚夜间睡眠时间≥6.5 h的人数达96.1%,对照组为34.4%,差异有统计学意义(P<0.01)。结论:术前1d 6:00口服磷酸钠盐口服溶液进行肠道准备为最佳的肠道准备时间。既保证肠道清洁质量,同时保证睡眠质量。展开更多
We described the case report of a patient presented with no known predisposing factor, generalized malaise with vomiting, locked jaw, perioral paraesthesia, carpopedal spasm and a positive Chvostek’s sign which resul...We described the case report of a patient presented with no known predisposing factor, generalized malaise with vomiting, locked jaw, perioral paraesthesia, carpopedal spasm and a positive Chvostek’s sign which resulted from severe electrolyte disturbance at 5 hours after use of oral sodium phosphate solution (NaPO4) as bowel preparation for colonoscopy. On presentation, she developed hyperphosphatemia and symptomatic hypocalcaemia with serum phosphate of 1.84 mmol/L and adjusted calcium level 1.67 mmol/L respectively. Her symptoms subsided after immediate intravenous calcium gluconate followed by oral calcium supplement. The electrolyte disturbances were normalized with an uneventful clinical course. The potentially fatal complications of sodium phosphate solution which commonly prescribed as bowel preparation for conventional colonoscopy could develop though previously reported as uncommon in patients without predisposing factors, and should not be overlooked. Urgent assessment and immediate correction of electrolyte disturbances are needed. Recommendations on patient selection of use of sodium phosphate to minimize risk of developing adverse events are needed to incorporate in clinical protocols.展开更多
1例41岁女性患者因反复便血10余年拟行肠镜检查以明确诊断，口服磷酸钠盐口服溶液（45 ml 溶于750 ml 温水）进行肠道准备，9 h 后出现恶心、呕吐、头晕、乏力、精神差、神志淡漠。急查血电解质示钾3.0 mmol/ L，钠118 mmol/ L，氯92 mm...1例41岁女性患者因反复便血10余年拟行肠镜检查以明确诊断，口服磷酸钠盐口服溶液（45 ml 溶于750 ml 温水）进行肠道准备，9 h 后出现恶心、呕吐、头晕、乏力、精神差、神志淡漠。急查血电解质示钾3.0 mmol/ L，钠118 mmol/ L，氯92 mmol/ L。考虑为磷酸钠盐口服溶液致电解质紊乱引起的低渗性脑病。相继给予静脉滴注10%氯化钾注射液、门冬氨酸钾镁注射液、10%氯化钠注射液、甘油果糖注射液。21 h 后患者神志转清，约27 h 后复查电解质示钾4.35 mmol/ L，钠130 mmol/ L，氯109 mmol/ L，钙2.15 mmol/ L。展开更多
文摘目的:探讨术前不同时间口服磷酸钠盐溶液进行肠道准备时对患者夜间睡眠质量的影响。方法:选取2014年7月至2015年10月广西壮族自治区人民医院收治的选择术前需要肠道准备的择期手术患者360例,随机分为观察组和对照组,每组180例,均用磷酸钠盐口服溶液45 m L加温开水250 m L后服用,进行肠道准备,观察组术前1 d 16:00服用;对照组术前1d 19:00服用。应用国际上常用的Athens失眠量表评价2组患者手术前晚睡眠质量情况。结果:观察组Athens评分显著低于对照组,观察组当晚夜间睡眠时间≥6.5 h的人数达96.1%,对照组为34.4%,差异有统计学意义(P<0.01)。结论:术前1d 6:00口服磷酸钠盐口服溶液进行肠道准备为最佳的肠道准备时间。既保证肠道清洁质量,同时保证睡眠质量。
文摘We described the case report of a patient presented with no known predisposing factor, generalized malaise with vomiting, locked jaw, perioral paraesthesia, carpopedal spasm and a positive Chvostek’s sign which resulted from severe electrolyte disturbance at 5 hours after use of oral sodium phosphate solution (NaPO4) as bowel preparation for colonoscopy. On presentation, she developed hyperphosphatemia and symptomatic hypocalcaemia with serum phosphate of 1.84 mmol/L and adjusted calcium level 1.67 mmol/L respectively. Her symptoms subsided after immediate intravenous calcium gluconate followed by oral calcium supplement. The electrolyte disturbances were normalized with an uneventful clinical course. The potentially fatal complications of sodium phosphate solution which commonly prescribed as bowel preparation for conventional colonoscopy could develop though previously reported as uncommon in patients without predisposing factors, and should not be overlooked. Urgent assessment and immediate correction of electrolyte disturbances are needed. Recommendations on patient selection of use of sodium phosphate to minimize risk of developing adverse events are needed to incorporate in clinical protocols.
文摘1例41岁女性患者因反复便血10余年拟行肠镜检查以明确诊断，口服磷酸钠盐口服溶液（45 ml 溶于750 ml 温水）进行肠道准备，9 h 后出现恶心、呕吐、头晕、乏力、精神差、神志淡漠。急查血电解质示钾3.0 mmol/ L，钠118 mmol/ L，氯92 mmol/ L。考虑为磷酸钠盐口服溶液致电解质紊乱引起的低渗性脑病。相继给予静脉滴注10%氯化钾注射液、门冬氨酸钾镁注射液、10%氯化钠注射液、甘油果糖注射液。21 h 后患者神志转清，约27 h 后复查电解质示钾4.35 mmol/ L，钠130 mmol/ L，氯109 mmol/ L，钙2.15 mmol/ L。
