目的比较中重度宫腔粘连分离术(transcervical resection of adhesion,TCRA)后两种预防宫腔再粘连方法的临床效果。方法回顾性分析2014年9月至2016年11月在深圳市宝安区妇幼保健院确诊为中重度宫腔粘连(intrauterine adhesions,IUA)的12...目的比较中重度宫腔粘连分离术(transcervical resection of adhesion,TCRA)后两种预防宫腔再粘连方法的临床效果。方法回顾性分析2014年9月至2016年11月在深圳市宝安区妇幼保健院确诊为中重度宫腔粘连(intrauterine adhesions,IUA)的120例患者的病例资料,随机分为A组57例、B组63例。两组患者术后均使用人工周期+阿司匹林肠溶片,A组术后宫腔放置宫内节育器+透明质酸钠,B组术后宫腔放置Foley球囊导尿管+透明质酸钠,比较两组患者术后宫腔形态、月经改善及妊娠情况。结果中度IUA患者中,A组、B组的宫腔形态好转率分别为38.7%、51.5%,治愈率分别为19.4%、36.4%,再粘连率分别为67.7%、45.5%,月经改善有效率分别为54.8%、81.8%,妊娠率分别为36.4%、54.5%;重度IUA患者中,A组、B组的宫腔形态好转率分别为34.6%、46.4%,治愈率分别为11.5%、28.6%,再粘连率分别为84.6%、60.7%,月经改善有效率分别为38.5%、71.4%,妊娠率分别为11.1%、22.2%。以上各项疗效比较差异均有统计学意义(P<0.05)。结论中重度IUA分离术后使用Foley球囊导尿管+透明质酸钠组治疗效果优于宫内节育器+透明质酸钠,值得临床推广。展开更多
AIM： To determine the effects of the calcineurin inhibitors, cyclosporine and tacrolimus, on hepatitis C virus （HCV） replication and activity of recurrent hepatitis C in patients post liver transplantation. METHODS...AIM： To determine the effects of the calcineurin inhibitors, cyclosporine and tacrolimus, on hepatitis C virus （HCV） replication and activity of recurrent hepatitis C in patients post liver transplantation. METHODS： The data of a cohort of 107 patients who received liver transplantation for HCV-associated liver cirrhosis between 1999 and 2003 in our center were retrospectively analyzed. The level of serum HCV-RNA and the activity of recurrent hepatitis were compared between 47 patients who received either cyclosporine or tacrolimus as the primary immunosuppressive agent and an otherwise similar immunosuppressive regimen which did not lead to biliary complications within the first 12 mo after transplantation. RESULTS： HCV-RNA increased within 3 mo after transplantation but the differences between the cyclosporine group and the tacrolimus group were insignificant （P=0.49 at 12 too）. In addition, recurrent hepatitis as determined by serum transarninases and histological grading of portal inflammation and fibrosis showed no significant difference after 12 mo （P= 0.34）.CONCLUSION： Cyclosporine or tacrolimus as a primary immunosuppressive agent does not influence the induction or severity of recurrent hepatitis in HCV- infected patients after liver transplantation.展开更多
Traditional Chinese medicine （TCM）, an important component of complementary and alternative medicine, has evolved over thousands of years with its own unique system of theories, diagnostics and therapies. TCM has be...Traditional Chinese medicine （TCM）, an important component of complementary and alternative medicine, has evolved over thousands of years with its own unique system of theories, diagnostics and therapies. TCM has been increasingly used in the last decades and become well known for its significant role in preventing and treating cancer. We believe that TCM possesses advantages over Western medicine in specific aspects at a certain stage of cancer treatment. Here we summarize the advantages of TCM from three aspects： preventing tumorigenesis; attenuating toxicity and enhancing the treatment effect; and reducing tumor recurrence and metastasis.展开更多
文摘目的比较中重度宫腔粘连分离术(transcervical resection of adhesion,TCRA)后两种预防宫腔再粘连方法的临床效果。方法回顾性分析2014年9月至2016年11月在深圳市宝安区妇幼保健院确诊为中重度宫腔粘连(intrauterine adhesions,IUA)的120例患者的病例资料,随机分为A组57例、B组63例。两组患者术后均使用人工周期+阿司匹林肠溶片,A组术后宫腔放置宫内节育器+透明质酸钠,B组术后宫腔放置Foley球囊导尿管+透明质酸钠,比较两组患者术后宫腔形态、月经改善及妊娠情况。结果中度IUA患者中,A组、B组的宫腔形态好转率分别为38.7%、51.5%,治愈率分别为19.4%、36.4%,再粘连率分别为67.7%、45.5%,月经改善有效率分别为54.8%、81.8%,妊娠率分别为36.4%、54.5%;重度IUA患者中,A组、B组的宫腔形态好转率分别为34.6%、46.4%,治愈率分别为11.5%、28.6%,再粘连率分别为84.6%、60.7%,月经改善有效率分别为38.5%、71.4%,妊娠率分别为11.1%、22.2%。以上各项疗效比较差异均有统计学意义(P<0.05)。结论中重度IUA分离术后使用Foley球囊导尿管+透明质酸钠组治疗效果优于宫内节育器+透明质酸钠,值得临床推广。
文摘AIM： To determine the effects of the calcineurin inhibitors, cyclosporine and tacrolimus, on hepatitis C virus （HCV） replication and activity of recurrent hepatitis C in patients post liver transplantation. METHODS： The data of a cohort of 107 patients who received liver transplantation for HCV-associated liver cirrhosis between 1999 and 2003 in our center were retrospectively analyzed. The level of serum HCV-RNA and the activity of recurrent hepatitis were compared between 47 patients who received either cyclosporine or tacrolimus as the primary immunosuppressive agent and an otherwise similar immunosuppressive regimen which did not lead to biliary complications within the first 12 mo after transplantation. RESULTS： HCV-RNA increased within 3 mo after transplantation but the differences between the cyclosporine group and the tacrolimus group were insignificant （P=0.49 at 12 too）. In addition, recurrent hepatitis as determined by serum transarninases and histological grading of portal inflammation and fibrosis showed no significant difference after 12 mo （P= 0.34）.CONCLUSION： Cyclosporine or tacrolimus as a primary immunosuppressive agent does not influence the induction or severity of recurrent hepatitis in HCV- infected patients after liver transplantation.
文摘Traditional Chinese medicine （TCM）, an important component of complementary and alternative medicine, has evolved over thousands of years with its own unique system of theories, diagnostics and therapies. TCM has been increasingly used in the last decades and become well known for its significant role in preventing and treating cancer. We believe that TCM possesses advantages over Western medicine in specific aspects at a certain stage of cancer treatment. Here we summarize the advantages of TCM from three aspects： preventing tumorigenesis; attenuating toxicity and enhancing the treatment effect; and reducing tumor recurrence and metastasis.
