In order to obtain a molecular-targeting photosensitizer mediated by folate receptor,5-p-(4-aminobutoxyphenyl)-10,15,20-tri-p-methoxyphenylporphyrin was synthesized with a four-step procedure starting from p-hydroxybe...In order to obtain a molecular-targeting photosensitizer mediated by folate receptor,5-p-(4-aminobutoxyphenyl)-10,15,20-tri-p-methoxyphenylporphyrin was synthesized with a four-step procedure starting from p-hydroxybenzaldehyde,p-methoxybenzaldehyde and pyrrole,then,a novel folate-porphyrin compound was prepared through a condensation reaction of the aminoporphyrin with actived folic acid.Its structure was characterized by IR,UV-Vis,MS and 1HNMR spectra.展开更多
Porphyrins and methyl viologen(MV;) are widely used as a photosensitizer and an electron acceptor respectively in photoinduced electron transfer systems. Literatures covered numerous examples of photochemical studies ...Porphyrins and methyl viologen(MV;) are widely used as a photosensitizer and an electron acceptor respectively in photoinduced electron transfer systems. Literatures covered numerous examples of photochemical studies of porphyrins covalently linked to various electron acceptor units, such as viologen, which functioned as both a photosensitizer and an electron acceptor in the same molecule. However, the length of the linked chain between porphyrin and viologen is very important. To improve the rate of photoin-展开更多
文摘In order to obtain a molecular-targeting photosensitizer mediated by folate receptor,5-p-(4-aminobutoxyphenyl)-10,15,20-tri-p-methoxyphenylporphyrin was synthesized with a four-step procedure starting from p-hydroxybenzaldehyde,p-methoxybenzaldehyde and pyrrole,then,a novel folate-porphyrin compound was prepared through a condensation reaction of the aminoporphyrin with actived folic acid.Its structure was characterized by IR,UV-Vis,MS and 1HNMR spectra.
基金Supported by the National Natural Science Foundation of China
文摘Porphyrins and methyl viologen(MV;) are widely used as a photosensitizer and an electron acceptor respectively in photoinduced electron transfer systems. Literatures covered numerous examples of photochemical studies of porphyrins covalently linked to various electron acceptor units, such as viologen, which functioned as both a photosensitizer and an electron acceptor in the same molecule. However, the length of the linked chain between porphyrin and viologen is very important. To improve the rate of photoin-
