摘要
卟啉作为有机光敏基元中的一种,在光敏剂家族中扮演着很重要的角色,在生物界中广泛存在,具有生物可相容性。通过对四种卟啉类光敏剂的合成与单线态氧产生能力的比较,得出推电子基团、配位金属以及谱带红移的卟啉结构有利于单线态氧的产生,为下一阶段研究其医学应用奠定基础。
Porphyrins, as one of organic photosensitive moieties, play a very important role in the family of photosensitizers. They are widely found in the biological community and are biocompatible. In this paper, four porphyrin photosensitizers were synthesized and their singlet oxygen generation abilities were compared. The results showed that the porphyrin structures with electron-donating group, coordination metal and spectral band redshift were beneficial to the generation of singlet oxygen. This work lays the foundation for the next research on its medical application.
作者
张琰
赵三笑
汪彬
王金金
王晓蓉
张晓欣
周世嘉
ZHANG Yan;ZHAO San-xiao;WANG Bin;WANG Jin-jin;WANG Xiao-rong;ZHANG Xiao-xin;ZHOU Shi-jia(College of Chemistry,Chemical Engineering and Environmental Engineering,Liaoning Shihua University,Liaoning Fushun 113001,China;Fushun Academy of Environmental Sciences,Liaoning Fushun 113006,China)
出处
《当代化工》
CAS
2018年第10期2062-2065,共4页
Contemporary Chemical Industry
基金
2017年辽宁省科技厅博士科研启动基金(20170520158)
2016年辽宁省教育厅一般项目(L2016003)
辽宁石油化工大学引进人才科研启动基金项目(2016XJJ-010)
北方民族大学"粉体材料与特种陶瓷"重点实验室开放基金(1605)
关键词
卟啉
光敏剂
单线态氧
红移
Porphyrin
Photosensitizer
Singlet oxygen
Redshift
