BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHOD...BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHODS:A total of 1 310 patients,who had been admitted to six hospitals from January 2004 to January 2008,were divided into six groups according to different surgical methods:craniotomy through bone fl ap(group A),craniotomy through a small bone window(group B),stereotactic drilling drainage(group C1 and group C2),neuron-endoscopy operation(group D) and external ventricular drainage(group E) in consideration of hemorrhage position,hemorrhage volume and clinical practice. A retrospective analysis was made of surgical timing and curative effect of the surgical methods.RESULTS:The effectiveness rate of the methods was 74.12% for 1 310 patients after onemonth follow-up. In this series,the disability rate was 44.82% 3–6 months after the operation. Among the 1 310 patients,241(18.40%) patients died after the operation. If hematoma volume was >80 mL and the operation was performed within 3 hours,the mortality rate of group A was signifi cantly lower than that of groups B,C,D,and E(P<0.05). If hematoma volume was 50–80 mL and the operation was performed within 6–12 hours,the mortality rate of groups B and D was lower than that of groups A,C and E(P<0.05). If hematoma volume was 20–50 mL and the operation was performed within 6–24 hours,the mortality rate of group C was lower than that of groups A,B and D(P<0.05).CONCLUSIONS:Craniotomy through a bone f lap is suitable for patients with a large hematoma and hernia of the brain. Stereotactic drilling drainage is suggested for patients with hematoma volume less than 80 mL. The curative effect of HICH individualized treatment would be improved via the suitable selection of operation time and surgical method according to the position and volume of hemorrhage.展开更多
The use of multi-perspective and multi-scalar city networks has gradually developed into a range of critical approaches to understand spatial interactions and linkages. In particular, road linkages represent key chara...The use of multi-perspective and multi-scalar city networks has gradually developed into a range of critical approaches to understand spatial interactions and linkages. In particular, road linkages represent key characteristics of spatial dependence and distance decay, and are of great significance in depicting spatial relationships at the regional scale. Therefore, based on highway passenger flow data between prefecture-level administrative units, this paper attempted to identify the functional structures and regional impacts of city networks in China, and to further explore the spatial organization patterns of the existing functional regions, aiming to deepen our understanding of city network structures and to provide new cognitive perspectives for ongoing research. The research results lead to four key conclusions. First, city networks that are based on highway flows exhibit strong spatial dependence and hierarchical characteristics, to a large extent spatially coupled with the distributions of major megaregions in China. These phenomena are a reflection of spatial relationships at regional scales as well as core-periphery structure. Second, 19 communities that belong to an important type of spatial configuration are identified through community detection algorithm, and we suggest they are correspondingly urban economic regions within urban China. Their spatial metaphors include the administrative region economy, spatial spillover effects of megaregions, and core-periphery structure. Third, each community possesses a specific city network system and exhibits strong spatial dependence and various spatial organization patterns. Regional patterns have emerged as the result of multi-level, dynamic, and networked characteristics. Fourth, adopting a morphology-based perspective, the regional city network systems can be basically divided into monocentric, dual-nuclei, polycentric, and low-level equilibration spatial structures, while most are developing monocentrically.展开更多
基金supported by a grant from Shanghai Pudong New Area(PWZxkq2011-01)
文摘BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHODS:A total of 1 310 patients,who had been admitted to six hospitals from January 2004 to January 2008,were divided into six groups according to different surgical methods:craniotomy through bone fl ap(group A),craniotomy through a small bone window(group B),stereotactic drilling drainage(group C1 and group C2),neuron-endoscopy operation(group D) and external ventricular drainage(group E) in consideration of hemorrhage position,hemorrhage volume and clinical practice. A retrospective analysis was made of surgical timing and curative effect of the surgical methods.RESULTS:The effectiveness rate of the methods was 74.12% for 1 310 patients after onemonth follow-up. In this series,the disability rate was 44.82% 3–6 months after the operation. Among the 1 310 patients,241(18.40%) patients died after the operation. If hematoma volume was >80 mL and the operation was performed within 3 hours,the mortality rate of group A was signifi cantly lower than that of groups B,C,D,and E(P<0.05). If hematoma volume was 50–80 mL and the operation was performed within 6–12 hours,the mortality rate of groups B and D was lower than that of groups A,C and E(P<0.05). If hematoma volume was 20–50 mL and the operation was performed within 6–24 hours,the mortality rate of group C was lower than that of groups A,B and D(P<0.05).CONCLUSIONS:Craniotomy through a bone f lap is suitable for patients with a large hematoma and hernia of the brain. Stereotactic drilling drainage is suggested for patients with hematoma volume less than 80 mL. The curative effect of HICH individualized treatment would be improved via the suitable selection of operation time and surgical method according to the position and volume of hemorrhage.
基金National Natural Science Foundation of China,No.41530751,No.41471113,No.41601165
文摘The use of multi-perspective and multi-scalar city networks has gradually developed into a range of critical approaches to understand spatial interactions and linkages. In particular, road linkages represent key characteristics of spatial dependence and distance decay, and are of great significance in depicting spatial relationships at the regional scale. Therefore, based on highway passenger flow data between prefecture-level administrative units, this paper attempted to identify the functional structures and regional impacts of city networks in China, and to further explore the spatial organization patterns of the existing functional regions, aiming to deepen our understanding of city network structures and to provide new cognitive perspectives for ongoing research. The research results lead to four key conclusions. First, city networks that are based on highway flows exhibit strong spatial dependence and hierarchical characteristics, to a large extent spatially coupled with the distributions of major megaregions in China. These phenomena are a reflection of spatial relationships at regional scales as well as core-periphery structure. Second, 19 communities that belong to an important type of spatial configuration are identified through community detection algorithm, and we suggest they are correspondingly urban economic regions within urban China. Their spatial metaphors include the administrative region economy, spatial spillover effects of megaregions, and core-periphery structure. Third, each community possesses a specific city network system and exhibits strong spatial dependence and various spatial organization patterns. Regional patterns have emerged as the result of multi-level, dynamic, and networked characteristics. Fourth, adopting a morphology-based perspective, the regional city network systems can be basically divided into monocentric, dual-nuclei, polycentric, and low-level equilibration spatial structures, while most are developing monocentrically.
