目的编制1个内容简洁的躯体化症状疾病认知量表,并完善信效度检测,为非精神病性精神障碍患者的躯体化症状疾病认知评估提供新的工具。方法于2020年5月至2022年1月从四川省人民医院、四川省精神医学中心门诊及住院部选取伴有躯体化症状...目的编制1个内容简洁的躯体化症状疾病认知量表,并完善信效度检测,为非精神病性精神障碍患者的躯体化症状疾病认知评估提供新的工具。方法于2020年5月至2022年1月从四川省人民医院、四川省精神医学中心门诊及住院部选取伴有躯体化症状的非精神病性精神障碍患者473例,根据文献研究法、半结构式访谈法、现有疾病认知量表以及诸位精神科专家临床经验获取量表总条目池(n=46),再经过课题组讨论及德尔菲专家函询法对条目池进行修改形成预测量表。在203例患者中施测量表,根据项目分析的结果对预测量表条目进行筛选形成正式量表。使用探索性因子分析构建量表维度。在270例患者中施测正式量表,使用Cronbachα系数评估总量表和各维度的信度,Pearson相关分析法验证重测信度;使用AMOS软件构建结构方程模型验证量表结构效度,使用Pearson相关分析以PHQ-15、GAD-7、PHQ-9为效标验证量表的效标效度。结果共收集443例患者的有效信息,根据课题组讨论及专家函询结果最终获得36个条目的预测量表,根据项目分析的结果删除20个条目后获得正式量表,共16个条目,包括疾病困扰、症状理解、治疗态度、服药态度4个维度,可解释57.702%的变异率。量表总分与PHQ-15、GAD-7、PHQ-9的相关系数为0.395~0.506;验证性因子分析提示模型拟合较理想[χ^(2)/df=1.719,拟合优度指数(good of fit index,GFI)=0.922,比较适配指数(comparative fit index,CFI)=0.937,标准拟合指数(normed fit index,NFI)=0.865,增值适配指数(incremental fit index,IFI)=0.939,近似误差均方根(root mean square error of approximation,RMSEA)=0.055],效度良好。总量表和4个维度的内部一致性系数、重测信度相关系数分别为0.683~0.831、0.746~0.836,信度良好。结论新编制量表具有良好的信效度,能够用于测量非精神病性精神障碍患者对躯体化症状的疾病认知。展开更多
Malaria commonly causes fever in tropical Africa. In 2010, World Health Organization recommended parasitological diagnosis of malaria before treatment. Rapid Diagnostic Test (RDT) aims at making malaria diagnosis more...Malaria commonly causes fever in tropical Africa. In 2010, World Health Organization recommended parasitological diagnosis of malaria before treatment. Rapid Diagnostic Test (RDT) aims at making malaria diagnosis more accessible. The objective of this study was to assess knowledge, and perception of malaria rapid diagnostic test (mRDT), among doctors in a tertiary health facility. A descriptive, cross sectional study, conducted in October 2016, in a state University Teaching hospital, Enugu state, Nigeria. 86 doctors in the General Outpatient, Internal Medicine, and Paediatrics departments participated. 90.7% of respondents knew parasitological examination of blood is the certain method of making malaria diagnosis, 89.5% knew microscopy and RDT are methods for parasitological diagnosis, 91.9% knew mRDT is quick blood test for malaria, 54.7% knew mRDT is usually specific for one or more species of malaria, 46.5% knew mRDT detects circulating malaria parasite antigen, 29.1% knew mRDT is read 15 to 20 minutes after the test, 70.9% knew mRDT is not superior to microscopy, 79.1% knew mRDT is not 100% specific, 80.2% knew mRDT ought not be done always by Laboratory Scientists, and 66.3% knew more than one type of mRDT kit is available. On perception, 64.0% thought it was important to confirm diagnosis before commencing treatment, 90.7% perceived mRDT as being very useful, 96.5% did not perceive mRDT as endangering patients, 70.9% opinioned that presumptive diagnosis of malaria is not a better way of making diagnosis, 76.7% did not believe malaria diagnosis is always clear on listening to the patient, 90.7% did not perceive mRDT as being hazardous, 83.7% believe using mRDT can reduce the quantity of anti-malaria drugs consumed, and 94.2% opinioned that mRDT should be encouraged and promoted. Training and re-training of health workers shall greatly enhance mRDT use in implementing the WHO T3 Initiative, and ultimately eliminating malaria.展开更多
文摘目的编制1个内容简洁的躯体化症状疾病认知量表,并完善信效度检测,为非精神病性精神障碍患者的躯体化症状疾病认知评估提供新的工具。方法于2020年5月至2022年1月从四川省人民医院、四川省精神医学中心门诊及住院部选取伴有躯体化症状的非精神病性精神障碍患者473例,根据文献研究法、半结构式访谈法、现有疾病认知量表以及诸位精神科专家临床经验获取量表总条目池(n=46),再经过课题组讨论及德尔菲专家函询法对条目池进行修改形成预测量表。在203例患者中施测量表,根据项目分析的结果对预测量表条目进行筛选形成正式量表。使用探索性因子分析构建量表维度。在270例患者中施测正式量表,使用Cronbachα系数评估总量表和各维度的信度,Pearson相关分析法验证重测信度;使用AMOS软件构建结构方程模型验证量表结构效度,使用Pearson相关分析以PHQ-15、GAD-7、PHQ-9为效标验证量表的效标效度。结果共收集443例患者的有效信息,根据课题组讨论及专家函询结果最终获得36个条目的预测量表,根据项目分析的结果删除20个条目后获得正式量表,共16个条目,包括疾病困扰、症状理解、治疗态度、服药态度4个维度,可解释57.702%的变异率。量表总分与PHQ-15、GAD-7、PHQ-9的相关系数为0.395~0.506;验证性因子分析提示模型拟合较理想[χ^(2)/df=1.719,拟合优度指数(good of fit index,GFI)=0.922,比较适配指数(comparative fit index,CFI)=0.937,标准拟合指数(normed fit index,NFI)=0.865,增值适配指数(incremental fit index,IFI)=0.939,近似误差均方根(root mean square error of approximation,RMSEA)=0.055],效度良好。总量表和4个维度的内部一致性系数、重测信度相关系数分别为0.683~0.831、0.746~0.836,信度良好。结论新编制量表具有良好的信效度,能够用于测量非精神病性精神障碍患者对躯体化症状的疾病认知。
文摘Malaria commonly causes fever in tropical Africa. In 2010, World Health Organization recommended parasitological diagnosis of malaria before treatment. Rapid Diagnostic Test (RDT) aims at making malaria diagnosis more accessible. The objective of this study was to assess knowledge, and perception of malaria rapid diagnostic test (mRDT), among doctors in a tertiary health facility. A descriptive, cross sectional study, conducted in October 2016, in a state University Teaching hospital, Enugu state, Nigeria. 86 doctors in the General Outpatient, Internal Medicine, and Paediatrics departments participated. 90.7% of respondents knew parasitological examination of blood is the certain method of making malaria diagnosis, 89.5% knew microscopy and RDT are methods for parasitological diagnosis, 91.9% knew mRDT is quick blood test for malaria, 54.7% knew mRDT is usually specific for one or more species of malaria, 46.5% knew mRDT detects circulating malaria parasite antigen, 29.1% knew mRDT is read 15 to 20 minutes after the test, 70.9% knew mRDT is not superior to microscopy, 79.1% knew mRDT is not 100% specific, 80.2% knew mRDT ought not be done always by Laboratory Scientists, and 66.3% knew more than one type of mRDT kit is available. On perception, 64.0% thought it was important to confirm diagnosis before commencing treatment, 90.7% perceived mRDT as being very useful, 96.5% did not perceive mRDT as endangering patients, 70.9% opinioned that presumptive diagnosis of malaria is not a better way of making diagnosis, 76.7% did not believe malaria diagnosis is always clear on listening to the patient, 90.7% did not perceive mRDT as being hazardous, 83.7% believe using mRDT can reduce the quantity of anti-malaria drugs consumed, and 94.2% opinioned that mRDT should be encouraged and promoted. Training and re-training of health workers shall greatly enhance mRDT use in implementing the WHO T3 Initiative, and ultimately eliminating malaria.
