The regulation of gene expression by microRNAs(miRNAs) is a recently discovered pattern of gene regulation in animals and plants.MiRNAs have been implicated in various aspects of animal development and cell differenti...The regulation of gene expression by microRNAs(miRNAs) is a recently discovered pattern of gene regulation in animals and plants.MiRNAs have been implicated in various aspects of animal development and cell differentiation,such as early embryonic development,neuronal development,muscle development,and lymphocyte development,by the analysis of genetic deletions of individual miRNAs in mammals.These studies show that miRNAs are key regulators in animal development and are potential causes of human diseases.Here we review some recent discoveries about the functions of miRNAs in cell differentiation and development.展开更多
[Objective] The aim of this study was to investigate the development rule of muscle fiber in different duck breeds during various developmental stages. [Method] Cherry valley duck, Jinding duck, White muscory duck and...[Objective] The aim of this study was to investigate the development rule of muscle fiber in different duck breeds during various developmental stages. [Method] Cherry valley duck, Jinding duck, White muscory duck and Suma duck （ Cherry valley duck ♂ × Jinding duck ♀ ） were fed for 10 weeks to observe the ultrastructure of muscle fiber by electron microscope, and the myofibril diameter and sarcomere length were also determined. [Result] The myofibril diameter increased with ages. Sarcomere length and myofibril diameter did not change significantly with the increasing ages （P〉0.05）. The myofibril diameter of White muscory duck and Jinding duck were thicker, while that of Cherry valley cluck and Suma duck were thinner. Moreover, the sarcomere length of Suma duck and White muscory duck were longer, while that of Cherry valley duck and Jinding duck were shorter. Thus, the basic characteristics of ultrastructure of muscle fiber were consistent in these duck breeds.[Conclusion] The results have an important meaning for duck breeding.展开更多
基金Supported by National Key Basic Research and Development Program of China (Grant No.2005CB724602)Knowledge Innovation Project of the Chinese Academy of Sciences (Grant Nos.KSCX2-YW-R-096,KSCX1-YW-R-64)
文摘The regulation of gene expression by microRNAs(miRNAs) is a recently discovered pattern of gene regulation in animals and plants.MiRNAs have been implicated in various aspects of animal development and cell differentiation,such as early embryonic development,neuronal development,muscle development,and lymphocyte development,by the analysis of genetic deletions of individual miRNAs in mammals.These studies show that miRNAs are key regulators in animal development and are potential causes of human diseases.Here we review some recent discoveries about the functions of miRNAs in cell differentiation and development.
基金Supported by Key Project for Ministry of National Science and Tech-nique (2006BAD01A09)National 863 Project (2006AA10Z1D8)~~
文摘[Objective] The aim of this study was to investigate the development rule of muscle fiber in different duck breeds during various developmental stages. [Method] Cherry valley duck, Jinding duck, White muscory duck and Suma duck （ Cherry valley duck ♂ × Jinding duck ♀ ） were fed for 10 weeks to observe the ultrastructure of muscle fiber by electron microscope, and the myofibril diameter and sarcomere length were also determined. [Result] The myofibril diameter increased with ages. Sarcomere length and myofibril diameter did not change significantly with the increasing ages （P〉0.05）. The myofibril diameter of White muscory duck and Jinding duck were thicker, while that of Cherry valley cluck and Suma duck were thinner. Moreover, the sarcomere length of Suma duck and White muscory duck were longer, while that of Cherry valley duck and Jinding duck were shorter. Thus, the basic characteristics of ultrastructure of muscle fiber were consistent in these duck breeds.[Conclusion] The results have an important meaning for duck breeding.
