Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic inf...Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic information including worldwide incidence, prevalence, burden of health loss(disability-adjusted life year;DALYs) and mortality of larynx cancer was obtained from the Global Health Data Exchange(GHDx) database.Results: The current incidence, prevalence and mortality of laryngeal cancer are estimated at 2.76 cases/year per 100,000 inhabitants, 14.33 cases/year per 100,000 inhabitants and 1.66 deaths/year per 100,000 inhabitants,respectively, averaging 3.28 million DALYs each year. Incidence and prevalence have increased by 12% and 24%,respectively during the past 3 decades, whilst mortality has declined by around 5%. The epidemiologic burden of this malignancy is approximately 5-fold higher in males and increases in parallel with ageing, peaking after 65 years of age. Both incidence and mortality rates are higher in Europe and lower in Africa, but the ratio between deaths and incidence is the highest in Africa. Incidence has gradually declined in Europe during the past 3 decades, whilst it has increased in South-East Asia and Western Pacific. Cigarette smoking and alcohol abuse contribute for about 90% of overall worldwide mortality for laryngeal cancer.Conclusions: Laryngeal cancer still poses a high clinical and societal burden, with an escalating temporal trend not expected to reverse soon.展开更多
目的:观察布地奈德(Budeson ide)雾化吸入治疗急性喉炎的效果。方法:将101例急性喉炎患者随机分为两组,分别使用布地奈德雾化吸入、常规(4万单位庆大霉素∶12.5mg泼尼松龙∶20m l 0.9%NaC l溶液)超声雾化吸入,治疗后第7天进行动态喉镜...目的:观察布地奈德(Budeson ide)雾化吸入治疗急性喉炎的效果。方法:将101例急性喉炎患者随机分为两组,分别使用布地奈德雾化吸入、常规(4万单位庆大霉素∶12.5mg泼尼松龙∶20m l 0.9%NaC l溶液)超声雾化吸入,治疗后第7天进行动态喉镜复查及嗓音分析,了解声带恢复情况,比较两种治疗方法的效果。结果:布地奈德和常规超声雾化吸入的两组患者有效率分别为93.9%和78.8%。两组间疗效比较差异有显著性意义(P<0.05)。结论:布地奈德雾化吸入治疗急性喉炎的疗效优于常规超声雾化吸入。展开更多
目的气管内燃烧三级预防策略在支撑喉镜下CO_2激光手术中预防气管内燃烧这一并发症的意义。方法回顾1992年2月~2016年12月于北京同仁医院行支撑喉镜下CO_2激光手术的喉肿物患者,第一阶段1992年2月~2008年12月,第二阶段2009年1月~2016年1...目的气管内燃烧三级预防策略在支撑喉镜下CO_2激光手术中预防气管内燃烧这一并发症的意义。方法回顾1992年2月~2016年12月于北京同仁医院行支撑喉镜下CO_2激光手术的喉肿物患者,第一阶段1992年2月~2008年12月,第二阶段2009年1月~2016年12月。比较这两个阶段术中发生气管内燃烧的差别。结果 4例气管内燃烧均发生于第一阶段,其中3例为声门型喉癌,1例为声带息肉及任克水肿。第二阶段未发生气管内燃烧。2例激光打破套囊后被及时发现,但未更换气管插管,将吸入氧浓度百分比(fraction of inspiration O_2,FiO_2)从70%降至30%,盐水纱条填塞套囊上区后,继续行激光手术致气管内燃烧;另外2例术中未发现套囊破损,气管内燃烧发生时FiO_2为70%。1例出现颈段气管狭窄,需长期带气切套管;其余3例无严重术后并发症。结论支撑喉镜下CO_2激光手术中喉气管内燃爆的三级预防策略有利于防止气管内燃爆的发生。展开更多
文摘Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic information including worldwide incidence, prevalence, burden of health loss(disability-adjusted life year;DALYs) and mortality of larynx cancer was obtained from the Global Health Data Exchange(GHDx) database.Results: The current incidence, prevalence and mortality of laryngeal cancer are estimated at 2.76 cases/year per 100,000 inhabitants, 14.33 cases/year per 100,000 inhabitants and 1.66 deaths/year per 100,000 inhabitants,respectively, averaging 3.28 million DALYs each year. Incidence and prevalence have increased by 12% and 24%,respectively during the past 3 decades, whilst mortality has declined by around 5%. The epidemiologic burden of this malignancy is approximately 5-fold higher in males and increases in parallel with ageing, peaking after 65 years of age. Both incidence and mortality rates are higher in Europe and lower in Africa, but the ratio between deaths and incidence is the highest in Africa. Incidence has gradually declined in Europe during the past 3 decades, whilst it has increased in South-East Asia and Western Pacific. Cigarette smoking and alcohol abuse contribute for about 90% of overall worldwide mortality for laryngeal cancer.Conclusions: Laryngeal cancer still poses a high clinical and societal burden, with an escalating temporal trend not expected to reverse soon.
文摘目的:观察布地奈德(Budeson ide)雾化吸入治疗急性喉炎的效果。方法:将101例急性喉炎患者随机分为两组,分别使用布地奈德雾化吸入、常规(4万单位庆大霉素∶12.5mg泼尼松龙∶20m l 0.9%NaC l溶液)超声雾化吸入,治疗后第7天进行动态喉镜复查及嗓音分析,了解声带恢复情况,比较两种治疗方法的效果。结果:布地奈德和常规超声雾化吸入的两组患者有效率分别为93.9%和78.8%。两组间疗效比较差异有显著性意义(P<0.05)。结论:布地奈德雾化吸入治疗急性喉炎的疗效优于常规超声雾化吸入。
文摘目的气管内燃烧三级预防策略在支撑喉镜下CO_2激光手术中预防气管内燃烧这一并发症的意义。方法回顾1992年2月~2016年12月于北京同仁医院行支撑喉镜下CO_2激光手术的喉肿物患者,第一阶段1992年2月~2008年12月,第二阶段2009年1月~2016年12月。比较这两个阶段术中发生气管内燃烧的差别。结果 4例气管内燃烧均发生于第一阶段,其中3例为声门型喉癌,1例为声带息肉及任克水肿。第二阶段未发生气管内燃烧。2例激光打破套囊后被及时发现,但未更换气管插管,将吸入氧浓度百分比(fraction of inspiration O_2,FiO_2)从70%降至30%,盐水纱条填塞套囊上区后,继续行激光手术致气管内燃烧;另外2例术中未发现套囊破损,气管内燃烧发生时FiO_2为70%。1例出现颈段气管狭窄,需长期带气切套管;其余3例无严重术后并发症。结论支撑喉镜下CO_2激光手术中喉气管内燃爆的三级预防策略有利于防止气管内燃爆的发生。
