摘要
目的探讨喉结核的发病趋势和临床变化。方法回顾性分析复旦大学附属眼耳鼻喉科医院1993年1月至2006年4月间61例喉结核的临床资料。结果患者年龄17~88岁,平均(51.13±17.05)岁;病程8d^2年。声嘶为其主要症状(81.97%),全身症状不明显。声带为其主要病变部位,病变类型以增生型为主。34例喉部多部位病灶中55.9%(19/34)并发活动性肺结核,27例喉部单一病灶中62.96%(17/27)肺部正常。54例经病理活检确诊,余7例未行活检,但胸片均提示有急性粟粒性肺结核。初诊误诊率为65.57%(40/61)。全部患者确诊后均转至结核病院进行治疗。失访5例,其余56例均治愈。结论当今喉结核的局部病变形态不典型,全身症状不明显;原发性喉结核发病率有增多趋势,发病年龄有增高的趋势。对喉结核的诊断除详细了解病史及症状外,活组织病理检查是该病确诊的重要手段。
Objective To evaluate the trends and the clinical changes in laryngeal tuberculosis. Methods The clinical data of 61 patients with laryngeal tuberculosis from Jan 1993 to Apt 2006 in our hospital were studied retrospectively. Results The age of the patients ranged from 17 to 88 years, with a mean age of （51.13± 17.05） years. The course of disease was 8 days to 2 years. The prominent presenting symptom was dysphonia （81. 97%） either in isolation or accompanied by odynophagia （11.5 %） ,while systemic symptoms were relatively rare. Proliferation was the main type of lesions. Among 34 patients with multiple lesions in the larynx, 19 （55.9%） had active pulmonary tuberculosis, while 17 （62.96%） had normal lung status among 27 patients with single lesions in the larynx. 54 cases were diagnosed pathologically, 7 cases without biopsy had acute phthisis miliaris by X-ray exam. The incidence of misdiagnosis was 65.57% （40/61）. All the patients received a full course of antituberculosis treatment. The results of the antituberculosis medication were satisfactory in all 56 cases patients who were followed up, while 5 cases were lost for follow- up. Conclusions The local clinical manifestations of laryngeal tuberculosis is nonspecific, while the general manifestation is not apparent. The incidence of primary laryngeal tuberculosis is increasing, the age of the patients transform from young to old. The diagnosis of laryngeal tuberculosis depends on the detailed history taking and signs, histopathologic examination of biopsy is important.
出处
《复旦学报（医学版）》
CAS
CSCD
北大核心
2008年第1期139-141,共3页
Fudan University Journal of Medical Sciences
关键词
结核
喉
临床分析
活组织检查
tuberculosis, larynx
clinical analysis
biopsy
