Objective:To explore the usefulness of multishot diffusion tensor imaging(DTI)for evaluating the neurological function of patients with spinal cord tumors Methods:Routine magnetic resonance imaging and multishot DTI w...Objective:To explore the usefulness of multishot diffusion tensor imaging(DTI)for evaluating the neurological function of patients with spinal cord tumors Methods:Routine magnetic resonance imaging and multishot DTI were performed in five patients with spinal cord tumors.The values of fractional anisotropy(FA)and radial diffusivity(RD)were analyzed.Results:Multishot DTI of spinal cord tumors allowed for defining the margins of tumors and determining the relationship of tumors with the adjacent white matter structures of the spinal cord.Multishot DTI demonstrated significantly increased RD and decreased FA of spinal cord tumors compared with those of the normal spinal cord.Conclusions:Multishot DTI is a potentially useful modality for differentiating resectable tumors from nonresectable ones based on preoperative imaging alone as well as for differentiating intramedullary tumors from extramedullary ones.Further prospective studies are warranted to confirm these results.展开更多
Diffusion tensor imaging(DTI)technique can detect the dispersion of water molecules in the white matter of the spinal cord,the integrity of the spinal fiber bundle,and the pathological changes after injury.Clinically,...Diffusion tensor imaging(DTI)technique can detect the dispersion of water molecules in the white matter of the spinal cord,the integrity of the spinal fiber bundle,and the pathological changes after injury.Clinically,DTI is sensitive to acute and chronic spinal cord injuries,and is most commonly used for the diagnosis of cervical spondylotic myelopathy,multiple sclerosis,secondary brain damage after spinal cord injury,and spinal nerve root damage.In animal studies involving rats,monkeys,cattle,cats,pigs,dogs,etc.,DTI could quantitatively analyze the microstructural and pathological changes of the injured spinal cord and provide a powerful auxiliary diagnosis for behavioral evaluation.展开更多
文摘Objective:To explore the usefulness of multishot diffusion tensor imaging(DTI)for evaluating the neurological function of patients with spinal cord tumors Methods:Routine magnetic resonance imaging and multishot DTI were performed in five patients with spinal cord tumors.The values of fractional anisotropy(FA)and radial diffusivity(RD)were analyzed.Results:Multishot DTI of spinal cord tumors allowed for defining the margins of tumors and determining the relationship of tumors with the adjacent white matter structures of the spinal cord.Multishot DTI demonstrated significantly increased RD and decreased FA of spinal cord tumors compared with those of the normal spinal cord.Conclusions:Multishot DTI is a potentially useful modality for differentiating resectable tumors from nonresectable ones based on preoperative imaging alone as well as for differentiating intramedullary tumors from extramedullary ones.Further prospective studies are warranted to confirm these results.
文摘Diffusion tensor imaging(DTI)technique can detect the dispersion of water molecules in the white matter of the spinal cord,the integrity of the spinal fiber bundle,and the pathological changes after injury.Clinically,DTI is sensitive to acute and chronic spinal cord injuries,and is most commonly used for the diagnosis of cervical spondylotic myelopathy,multiple sclerosis,secondary brain damage after spinal cord injury,and spinal nerve root damage.In animal studies involving rats,monkeys,cattle,cats,pigs,dogs,etc.,DTI could quantitatively analyze the microstructural and pathological changes of the injured spinal cord and provide a powerful auxiliary diagnosis for behavioral evaluation.
文摘目的探讨首发未用药的偏执型精神分裂症患者的多个脑区白质磁共振弥散张量成像(diffusion tensor imaging,DTI)的特点,以期为精神分裂症"脑内连接异常的假说"提供依据。方法选取20例首发偏执型精神分裂症患者,应用DTI扫描,检测脑内21个感兴趣区(regions of interest,ROI)白质纤维的微细结构,并与20名年龄、性别和文化程度相匹配的正常对照比较。结果患者组额叶、内囊前肢、外囊的左右两侧FA值和左侧颞叶、左侧内囊膝部、胼胝体膝部FA值小于对照组(P<0.05)。患者组额叶左右侧FA值差异无统计学意义(P>0.05),而对照组左侧大于右侧(P<0.05);患者组内囊膝部和后肢FA值右侧大于左侧(P<0.05),而对照组左侧大于右侧(P<0.05)。患者组双侧外囊FA值均小于对照组(P<0.05)。结论未用药首发偏执型精神分裂症患者脑内多个白质区部分各向异性降低,尤其是额叶皮层下环路更加显著,数个白质区部分各向异性的正常"左>右"的偏侧性缺失或倒置,支持精神分裂症脑内连接异常的神经病理假说。