Sulfide-containing waste streams are generated by a number of industries. It is emitted into the environment as dis- solved sulfide (S2- and HS-) in wastewaters and as H2S in waste gases. Due to its corrosive nature, ...Sulfide-containing waste streams are generated by a number of industries. It is emitted into the environment as dis- solved sulfide (S2- and HS-) in wastewaters and as H2S in waste gases. Due to its corrosive nature, biological hydrogen sulfide removal processes are being investigated to overcome the chemical and disposal costs associated with existing chemically based removal processes. The nitrogen and sulfur metabolism interacts at various levels of the wastewater treatment process. Hence, the sulfur cycle offers possibilities to integrate nitrogen removal in the treatment process, which needs to be further optimized by appropriate design of the reactor configuration, optimization of performance parameters, retention of biomass and optimization of biomass growth. The present paper reviews the biotechnological advances to remove sulfides from various environments.展开更多
背景:外源性硫化氢(H_(2)S)对成骨细胞的形成和分化有重要的影响,成骨细胞是骨质疏松疾病发生发展的重要功能细胞,而外源性H_(2)S对骨质疏松水平及相关激素的影响尚未见研究。目的:探讨内源性H_(2)S浓度与骨质疏松的相关性,以及补充外源...背景:外源性硫化氢(H_(2)S)对成骨细胞的形成和分化有重要的影响,成骨细胞是骨质疏松疾病发生发展的重要功能细胞,而外源性H_(2)S对骨质疏松水平及相关激素的影响尚未见研究。目的:探讨内源性H_(2)S浓度与骨质疏松的相关性,以及补充外源性H_(2)S对骨代谢临床随访常用生化、激素指标的影响。方法:纳入60只大鼠,随机分为3组(n=20),模型组、外源性H_(2)S组通过切除大鼠双侧卵巢建立经典的骨质疏松模型,假手术组进行假手术处理,不做卵巢切除术。假手术组、模型组大鼠腹腔注射1 mg/kg生理盐水,外源性H_(2)S组大鼠腹腔注射100μg/kg外源性H_(2)S缓释剂GYY4137,用药频率均为2 d 1次,实验期为12周。定量对比分析各组大鼠血浆H_(2)S水平、血钙和血磷浓度以及血浆碱性磷酸酶活性、骨钙素、降钙素、甲状旁腺素、瘦素表达水平。结果与结论:①与假手术组相比,给药第8,12周模型组大鼠L5骨密度、血浆H_(2)S、钙、磷、碱性磷酸酶、降钙素水平显著降低,骨钙素、甲状旁腺素、瘦素水平则显著升高(P<0.05);②与假手术组相比,给药第8,12周外源性H_(2)S组L5骨密度、血浆H_(2)S、磷、骨钙素、降钙素、甲状旁腺素和瘦素差异无显著性意义(P>0.05),而血浆钙水平、碱性磷酸酶活性仍降低(P<0.05);③与模型组相比,外源性H_(2)S组血浆H_(2)S、钙、磷水平升高,瘦素水平降低(P<0.05),而给药第8,12周L5骨密度、碱性磷酸酶活性、骨钙素、降钙素、甲状旁腺素水平差异均无显著性意义(P>0.05);④结果表明,内源性H_(2)S浓度与去势大鼠骨质疏松模型的骨质疏松病情呈现负相关关系,外源性补充提高血浆H_(2)S浓度可以改善或反转血浆钙、磷和部分骨代谢激素指标水平;提示血浆H_(2)S浓度与骨质疏松存在相关性,补充外源性H_(2)S对因雌激素减少导致的骨质疏松症具有潜在治疗效果。展开更多
基金Project supported by the National Natural Science Foundation ofChina (No. 30070017)the Science and Technology Foundationfor Key Project of Zhejiang Province (No. 2003C13005), China
文摘Sulfide-containing waste streams are generated by a number of industries. It is emitted into the environment as dis- solved sulfide (S2- and HS-) in wastewaters and as H2S in waste gases. Due to its corrosive nature, biological hydrogen sulfide removal processes are being investigated to overcome the chemical and disposal costs associated with existing chemically based removal processes. The nitrogen and sulfur metabolism interacts at various levels of the wastewater treatment process. Hence, the sulfur cycle offers possibilities to integrate nitrogen removal in the treatment process, which needs to be further optimized by appropriate design of the reactor configuration, optimization of performance parameters, retention of biomass and optimization of biomass growth. The present paper reviews the biotechnological advances to remove sulfides from various environments.
文摘背景:外源性硫化氢(H_(2)S)对成骨细胞的形成和分化有重要的影响,成骨细胞是骨质疏松疾病发生发展的重要功能细胞,而外源性H_(2)S对骨质疏松水平及相关激素的影响尚未见研究。目的:探讨内源性H_(2)S浓度与骨质疏松的相关性,以及补充外源性H_(2)S对骨代谢临床随访常用生化、激素指标的影响。方法:纳入60只大鼠,随机分为3组(n=20),模型组、外源性H_(2)S组通过切除大鼠双侧卵巢建立经典的骨质疏松模型,假手术组进行假手术处理,不做卵巢切除术。假手术组、模型组大鼠腹腔注射1 mg/kg生理盐水,外源性H_(2)S组大鼠腹腔注射100μg/kg外源性H_(2)S缓释剂GYY4137,用药频率均为2 d 1次,实验期为12周。定量对比分析各组大鼠血浆H_(2)S水平、血钙和血磷浓度以及血浆碱性磷酸酶活性、骨钙素、降钙素、甲状旁腺素、瘦素表达水平。结果与结论:①与假手术组相比,给药第8,12周模型组大鼠L5骨密度、血浆H_(2)S、钙、磷、碱性磷酸酶、降钙素水平显著降低,骨钙素、甲状旁腺素、瘦素水平则显著升高(P<0.05);②与假手术组相比,给药第8,12周外源性H_(2)S组L5骨密度、血浆H_(2)S、磷、骨钙素、降钙素、甲状旁腺素和瘦素差异无显著性意义(P>0.05),而血浆钙水平、碱性磷酸酶活性仍降低(P<0.05);③与模型组相比,外源性H_(2)S组血浆H_(2)S、钙、磷水平升高,瘦素水平降低(P<0.05),而给药第8,12周L5骨密度、碱性磷酸酶活性、骨钙素、降钙素、甲状旁腺素水平差异均无显著性意义(P>0.05);④结果表明,内源性H_(2)S浓度与去势大鼠骨质疏松模型的骨质疏松病情呈现负相关关系,外源性补充提高血浆H_(2)S浓度可以改善或反转血浆钙、磷和部分骨代谢激素指标水平;提示血浆H_(2)S浓度与骨质疏松存在相关性,补充外源性H_(2)S对因雌激素减少导致的骨质疏松症具有潜在治疗效果。
