目的:观察中医六字诀训练结合西医常规治疗慢性阻塞性肺疾病的临床疗效。方法:将Ⅱ期和Ⅲ期慢性阻塞性肺疾病患者40例按照1:1比例随机分为六字诀组和对照组。六字诀组患者在西医常规治疗的基础上进行6个月的六字诀训练,每周训练6次,每...目的:观察中医六字诀训练结合西医常规治疗慢性阻塞性肺疾病的临床疗效。方法:将Ⅱ期和Ⅲ期慢性阻塞性肺疾病患者40例按照1:1比例随机分为六字诀组和对照组。六字诀组患者在西医常规治疗的基础上进行6个月的六字诀训练,每周训练6次,每次训练60 min。对照组患者只接受西医常规治疗,不进行任何运动训练。评价治疗前后两组患者肺功能、6分钟步行距离(6 minutes walking distance,6 MWD)、30 s坐立次数试验(sit and stand test for 30 seconds,30 s SST)和圣乔治呼吸问卷(St George’s respiratory questionnaire,SGRQ)生活质量。结果:六字诀组患者治疗后肺功能、6 MWD、30 s SST和生活质量均较治疗前改善(P<0.05);对照组患者治疗后肺功能、6 MWD、30 s SST与治疗前比较无显著差异(P>0.05),生活质量较治疗前下降(P<0.05)。治疗后六字诀组患者第一秒用力呼气容积占预计值百分比(forced expiratory volume in one second,FEV1/pred%)、6 MWD、30 s SST和生活质量高于对照组(P<0.05)。结论:中医六字诀训练结合西医常规治疗能改善慢性阻塞性肺疾病患者肺功能、运动能力和生活质量。展开更多
Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience.The function of the neural pathway under the damaged sites can be rebuilt using functio...Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience.The function of the neural pathway under the damaged sites can be rebuilt using functional electrical stimulation technology.In this study,the locations of motor function sites in the lumbosacral spinal cord were determined with functional electrical stimulation technology.A three-dimensional map of the lumbosacral spinal cord comprising the relationship between the motor function sites and the corresponding muscle was drawn.Based on the individual experimental parameters and normalized coordinates of the motor function sites,the motor function sites that control a certain muscle were calculated.Phasing pulse sequences were delivered to the determined motor function sites in the spinal cord and hip extension,hip flexion,ankle plantarflexion,and ankle dorsiflexion movements were successfully achieved.The results show that the map of the spinal cord motor function sites was valid.This map can provide guidance for the selection of electrical stimulation sites during the rebuilding of motor function after spinal cord injury.展开更多
文摘目的:观察中医六字诀训练结合西医常规治疗慢性阻塞性肺疾病的临床疗效。方法:将Ⅱ期和Ⅲ期慢性阻塞性肺疾病患者40例按照1:1比例随机分为六字诀组和对照组。六字诀组患者在西医常规治疗的基础上进行6个月的六字诀训练,每周训练6次,每次训练60 min。对照组患者只接受西医常规治疗,不进行任何运动训练。评价治疗前后两组患者肺功能、6分钟步行距离(6 minutes walking distance,6 MWD)、30 s坐立次数试验(sit and stand test for 30 seconds,30 s SST)和圣乔治呼吸问卷(St George’s respiratory questionnaire,SGRQ)生活质量。结果:六字诀组患者治疗后肺功能、6 MWD、30 s SST和生活质量均较治疗前改善(P<0.05);对照组患者治疗后肺功能、6 MWD、30 s SST与治疗前比较无显著差异(P>0.05),生活质量较治疗前下降(P<0.05)。治疗后六字诀组患者第一秒用力呼气容积占预计值百分比(forced expiratory volume in one second,FEV1/pred%)、6 MWD、30 s SST和生活质量高于对照组(P<0.05)。结论:中医六字诀训练结合西医常规治疗能改善慢性阻塞性肺疾病患者肺功能、运动能力和生活质量。
基金supported by the National Natural Science Foundation of China,No.81371663,61534003the Top-notch Academic Programs Project of Jiangsu Higher Education Institutions of China,No.PPZY2015B135
文摘Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience.The function of the neural pathway under the damaged sites can be rebuilt using functional electrical stimulation technology.In this study,the locations of motor function sites in the lumbosacral spinal cord were determined with functional electrical stimulation technology.A three-dimensional map of the lumbosacral spinal cord comprising the relationship between the motor function sites and the corresponding muscle was drawn.Based on the individual experimental parameters and normalized coordinates of the motor function sites,the motor function sites that control a certain muscle were calculated.Phasing pulse sequences were delivered to the determined motor function sites in the spinal cord and hip extension,hip flexion,ankle plantarflexion,and ankle dorsiflexion movements were successfully achieved.The results show that the map of the spinal cord motor function sites was valid.This map can provide guidance for the selection of electrical stimulation sites during the rebuilding of motor function after spinal cord injury.