1癌症研究现状与精准医学
过去一百多年,各国对肿瘤浩浩荡荡的研究并没有取得突破性进展,就如Leaf^([1])在2004年Fortune所提到:"Why We're Losing the War on Cancer——and How to Win it?”。近10多年来,基因组学、功能基因...1癌症研究现状与精准医学
过去一百多年,各国对肿瘤浩浩荡荡的研究并没有取得突破性进展,就如Leaf^([1])在2004年Fortune所提到:"Why We're Losing the War on Cancer——and How to Win it?”。近10多年来,基因组学、功能基因组学、高通量生物芯片、新一代测序及生物信息学、高通量RNAi等前沿技术的迅猛发展,国际癌症基因组(ICGC)项目的启动,使得我们将有机会看清肿瘤的全貌,一直在不断重演的“盲人摸象”式研究的历史有望结束。展开更多
Simphiwe Zondi in Johannesburg,South Africa,was especially happy on 16 April.At the 2024 Job Fair of the Chinese-Invested Enterprises in South Africa held in the Gallagher Convention Centre on that day,he presented hi...Simphiwe Zondi in Johannesburg,South Africa,was especially happy on 16 April.At the 2024 Job Fair of the Chinese-Invested Enterprises in South Africa held in the Gallagher Convention Centre on that day,he presented his CV and immediately secured a job as a technical director at the South Africa subsidiary of PowerChina,which ranked 105th on the Fortune Global 500 list in 2023.He was one of the few applicants who signed employment contracts at the job fair.展开更多
The improvement of infrastructure has allowed the express logistics network to extend from cities to villages,and from China to the entire world.LOGISTICS is the last great unexplored continent of business,American gu...The improvement of infrastructure has allowed the express logistics network to extend from cities to villages,and from China to the entire world.LOGISTICS is the last great unexplored continent of business,American guru Peter Drucker forecasted in Fortune magazine in 1962.展开更多
"Picking persimmons,making persimmon cakes,everything is going smoothly!"Every autumn at"Shizi An(or Persimmon Temple),"a small temple hidden in the deep mountains,the persimmon trees in the courty..."Picking persimmons,making persimmon cakes,everything is going smoothly!"Every autumn at"Shizi An(or Persimmon Temple),"a small temple hidden in the deep mountains,the persimmon trees in the courtyard are full of red fruit-like lanterns,tempting everyone to pick them.The author,Uncle Peach,and the illustrator,Fei Jingmiao,have teamed up to create this delightful world that will make you feel the warmth of human nature and the joy of harvest with all living creatures.With love in our hearts,we will never feel cold in the mountains.展开更多
From November 5 to 10,the sixth China International Import Expo(CIIE),themed“New Era,Shared Future,”took place in Shanghai.It was the first fully offline edition of CIIE since the COVID-19 pandemic.This year,69 coun...From November 5 to 10,the sixth China International Import Expo(CIIE),themed“New Era,Shared Future,”took place in Shanghai.It was the first fully offline edition of CIIE since the COVID-19 pandemic.This year,69 countries and three international organizations participated in the Country Exhibition,with 11 countries participating for the first time and 34 countries participating offline for the first time.Sheng Qiuping,Chinese vice minister of commerce,said at a news conference that the sixth CIIE would cover over 367,000 square meters and feature participation from a record 289 Fortune Global 500 companies and industry-leading businesses.展开更多
Climate change is affecting global crop productivity, food quality, and security. However,few studies have addressed the mechanism by which elevated CO_2 may affect the growth of medicinal plants. Isatis indigotica Fo...Climate change is affecting global crop productivity, food quality, and security. However,few studies have addressed the mechanism by which elevated CO_2 may affect the growth of medicinal plants. Isatis indigotica Fortune is a widely used Chinese medicinal herb with multiple pharmacological properties. To investigate the physiological mechanism of I.indigotica response to elevated [CO_2], plants were grown at either ambient [CO_2](385 μmol mol^(-1)) or elevated [CO_2] (590 μmol mol^(-1)) in an open-top chamber (OTC)experimental facility in North China. A significant reduction in transpiration rate (T_r) and stomatal conductance (g_s) and a large increase in water-use efficiency contributed to an increase in net photosynthetic rate (Pn) under elevated [CO_2] 76 days after sowing. Leaf non-photochemical quenching (NPQ) was decreased, so that more energy was used in effective quantum yield of PSII photochemistry (Φ_(PSⅡ)) under elevated [CO_2]. High ΦPSII,meaning high electron transfer efficiency, also increased Pn. The [CO_2]-induced increase in photosynthesis significantly increased biomass by 36.8%. Amounts of metabolic compounds involved in sucrose metabolism, pyrimidine metabolism, flavonoid biosynthesis, and other processes in leaves were reduced under elevated [CO_2]. These results showed that the fertilization effect of elevated [CO_2] is conducive to increasing dry weight but not secondary metabolism in I. indigotica.展开更多
文摘1癌症研究现状与精准医学
过去一百多年,各国对肿瘤浩浩荡荡的研究并没有取得突破性进展,就如Leaf^([1])在2004年Fortune所提到:"Why We're Losing the War on Cancer——and How to Win it?”。近10多年来,基因组学、功能基因组学、高通量生物芯片、新一代测序及生物信息学、高通量RNAi等前沿技术的迅猛发展,国际癌症基因组(ICGC)项目的启动,使得我们将有机会看清肿瘤的全貌,一直在不断重演的“盲人摸象”式研究的历史有望结束。
文摘Simphiwe Zondi in Johannesburg,South Africa,was especially happy on 16 April.At the 2024 Job Fair of the Chinese-Invested Enterprises in South Africa held in the Gallagher Convention Centre on that day,he presented his CV and immediately secured a job as a technical director at the South Africa subsidiary of PowerChina,which ranked 105th on the Fortune Global 500 list in 2023.He was one of the few applicants who signed employment contracts at the job fair.
文摘The improvement of infrastructure has allowed the express logistics network to extend from cities to villages,and from China to the entire world.LOGISTICS is the last great unexplored continent of business,American guru Peter Drucker forecasted in Fortune magazine in 1962.
文摘"Picking persimmons,making persimmon cakes,everything is going smoothly!"Every autumn at"Shizi An(or Persimmon Temple),"a small temple hidden in the deep mountains,the persimmon trees in the courtyard are full of red fruit-like lanterns,tempting everyone to pick them.The author,Uncle Peach,and the illustrator,Fei Jingmiao,have teamed up to create this delightful world that will make you feel the warmth of human nature and the joy of harvest with all living creatures.With love in our hearts,we will never feel cold in the mountains.
文摘From November 5 to 10,the sixth China International Import Expo(CIIE),themed“New Era,Shared Future,”took place in Shanghai.It was the first fully offline edition of CIIE since the COVID-19 pandemic.This year,69 countries and three international organizations participated in the Country Exhibition,with 11 countries participating for the first time and 34 countries participating offline for the first time.Sheng Qiuping,Chinese vice minister of commerce,said at a news conference that the sixth CIIE would cover over 367,000 square meters and feature participation from a record 289 Fortune Global 500 companies and industry-leading businesses.
基金partially supported by the National Natural Science Foundation of China (Nos. 31601212, 31371693, and 31471556)Research on Science and Technology of Shanxi Province (No. 20150311006-2)+1 种基金Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi (No. 2015146)the Shanxi 100-Talent Program
文摘Climate change is affecting global crop productivity, food quality, and security. However,few studies have addressed the mechanism by which elevated CO_2 may affect the growth of medicinal plants. Isatis indigotica Fortune is a widely used Chinese medicinal herb with multiple pharmacological properties. To investigate the physiological mechanism of I.indigotica response to elevated [CO_2], plants were grown at either ambient [CO_2](385 μmol mol^(-1)) or elevated [CO_2] (590 μmol mol^(-1)) in an open-top chamber (OTC)experimental facility in North China. A significant reduction in transpiration rate (T_r) and stomatal conductance (g_s) and a large increase in water-use efficiency contributed to an increase in net photosynthetic rate (Pn) under elevated [CO_2] 76 days after sowing. Leaf non-photochemical quenching (NPQ) was decreased, so that more energy was used in effective quantum yield of PSII photochemistry (Φ_(PSⅡ)) under elevated [CO_2]. High ΦPSII,meaning high electron transfer efficiency, also increased Pn. The [CO_2]-induced increase in photosynthesis significantly increased biomass by 36.8%. Amounts of metabolic compounds involved in sucrose metabolism, pyrimidine metabolism, flavonoid biosynthesis, and other processes in leaves were reduced under elevated [CO_2]. These results showed that the fertilization effect of elevated [CO_2] is conducive to increasing dry weight but not secondary metabolism in I. indigotica.