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慢性下腰痛临床病因学研究 被引量:26
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作者 李亨 郑军 《亚太传统医药》 2016年第20期49-51,共3页
慢性下腰痛是骨科临床、针灸推拿及康复医学面临的常见疾病。慢性下腰痛的病因纷繁复杂,给临床诊疗带来巨大挑战,由于慢性下腰痛的临床特殊性,其被一线临床工作者称为"不死的癌症"。通过对现有国内外有关慢性下腰痛病因学分... 慢性下腰痛是骨科临床、针灸推拿及康复医学面临的常见疾病。慢性下腰痛的病因纷繁复杂,给临床诊疗带来巨大挑战,由于慢性下腰痛的临床特殊性,其被一线临床工作者称为"不死的癌症"。通过对现有国内外有关慢性下腰痛病因学分类研究的文献进行综述,归纳总结慢性下腰痛的常见病因,以期能更好地为临床一线工作者诊疗该疾病提供参考依据。 展开更多
关键词 慢性下腰痛 病因学 综述
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Non-viral factors contributing to hepatocellular carcinoma 被引量:7
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作者 Manal A Hamed Sanaa A Ali 《World Journal of Hepatology》 CAS 2013年第6期311-322,共12页
Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide, accounting for over half a million deaths per year. The geographic pattern of HCC incidence is parallel to exposure to viral etiologic factors... Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide, accounting for over half a million deaths per year. The geographic pattern of HCC incidence is parallel to exposure to viral etiologic factors. Its incidence is increasing, ranging between 3% and 9% annually depending on the geographical location, and variability in the incidence rates correspond closely to the prevalence and pattern of the primary etiologic factors. Chronic infections with hepatitis B viruses or hepatitis C viruses have both been recognized as human liver carcinogens with a combined attributable fraction of at least 75% of all HCC cases. Multiple non-viral factors have been implicated in the development of HCC. Increased body mass index and diabetes with subsequent development of non-alcoholic steatohepatitis represent significant risk factors for HCC. Other non-viral causes of HCC include iron overload syndromes, alcohol use, tobacco, oral contraceptive, aflatoxin, pesticides exposure and betel quid chewing, a prevalent habit in the developing world. Wilson disease, α-1 antitrypsin deficiency, Porphyrias, autoimmune hepatitis, Schistosoma japonicum associated with positive hepatitis B surface antigen, and thorotrastray are also contributing hepatocellualar carcinoma. In addition, primary biliary cirrhosis, congestive liver disease and family history of liver cancer increase the risk of HCC incident. In conclusion,clarification of relevant non-viral causes of HCC will help to focus clinicians on those risk factors that are modifiable. The multilevel preventative approach will hopefully lead to a reduction in incidence of non-viral HCC, and a decrease in the patient morbidity and mortality as well as the societal economic burden associated with HCC. 展开更多
关键词 HEPATOCELLULAR CARCINOMA VIRAL etiologic FACTORS Non VIRAL FACTORS
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Antibiotic Susceptibility Patterns of Isolated Bacteria from Otitis Media in Children at Mohamed Aden Sheikh Children Teaching Hospital in Hargeisa, Somaliland
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作者 Saed N. Ahmed 《Journal of Biosciences and Medicines》 2023年第6期57-70,共14页
Background: Otitis media (OM) is a group of inflammatory diseases of the middle ear. OM is a prevailing problem among children in Hargeisa. The antibiotic susceptibility of etiologic bacteria is not investigated in So... Background: Otitis media (OM) is a group of inflammatory diseases of the middle ear. OM is a prevailing problem among children in Hargeisa. The antibiotic susceptibility of etiologic bacteria is not investigated in Somaliland which hinders the effective treatment of OM cases in children. Objective: This study aimed at determining the etiologic bacteria and its antibiotic susceptibilities in children presenting with OM to a pediatric referral hospital in Hargeisa for the period March 2013-May 2017. Methods: A cross-sectional retrospective study was conducted on a random sample of 270 children with OM. The laboratory used standard microbiological techniques for bacterial isolation and Kirby Bauer disk diffusion method for antibiotic susceptibility testing. Data were entered and analyzed using Epi Info 7 and any associations among the study variables tested with Chi2 test with confidence level of 95% and p value of Results: The rate of bacterial isolation was 96.3%. The predominant bacterial isolate was S. aureus (31.48%) followed by P. aeruginosa (24.81%) and P. mirabilis (15.93%) respectively while the least prevalent isolates were coagulase negative Staphylococcus (1.48%), S. pyogenes (0.74%) and Enterobacter spp. (0.37%) in descending order. Age group 0 - 3, χ<sup>2</sup> (143,270 = 223.245, p = 0.000) showed highest bacterial isolation. There was no significant relationship between bacterial isolate and gender, χ<sup>2</sup> (11,270 = 9.2283, p = 0.6008). S. aureus showed highest sensitivity towards ciprofloxacin (85.7%), amikacin (76.5%), and gentamicin (73.8%). All isolates showed mixed resistance pattern. Conclusion: S. aureus, P. aeruginosa and P. mirabilis were the leading causative pathogens of otitis media. No association was established between isolate distribution and gender. Both the isolated gram-positive and gram-negative bacteria showed greatest sensitivity towards ciprofloxacin while the highest resistance was observed to penicillins, tetracyclines and sulfonamides. The Otitis Media among childr 展开更多
关键词 Otitis Media CHILDREN etiologic Bacteria Antibiotic Susceptibility TREATMENT
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112例肺不张纤维支气管镜检查结果分析 被引量:6
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作者 唐桑梓 《中国内镜杂志》 CSCD 2004年第12期63-64,共2页
目的研究纤维支气管镜在肺不张病因诊断方面的价值。方法对112例肺不张进行回顾性病因分析。结果112例肺不张纤支镜的病因检出分别是肿瘤43例(38.39%)、炎症34例(30.36%)、结核21例(18.75%)、异物5例(4.46 %)、原因不明9例(8.04%)。确诊... 目的研究纤维支气管镜在肺不张病因诊断方面的价值。方法对112例肺不张进行回顾性病因分析。结果112例肺不张纤支镜的病因检出分别是肿瘤43例(38.39%)、炎症34例(30.36%)、结核21例(18.75%)、异物5例(4.46 %)、原因不明9例(8.04%)。确诊103例,确诊率91.96%。结论纤支镜对肺不张的病因诊断确诊率高,简单易行且安全可靠,应及早介入。 展开更多
关键词 纤维支气管镜 肺不张 病因
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门诊120例慢性咳嗽患者的诊断和治疗结果分析 被引量:4
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作者 赵国厚 袁开芬 冯海葵 《中国医药导刊》 2008年第7期1006-1008,共3页
目的:分析和评价慢性咳嗽患者就诊规律、病因分布、诊断方法、治疗措施及效果,探讨适宜社区和基层的基本诊疗方法。方法:参考Irwin的慢性咳嗽解剖学诊断流程,对门诊120例慢性咳嗽患者的病因进行诊断分析,并按不同病因给予针对治疗。结果... 目的:分析和评价慢性咳嗽患者就诊规律、病因分布、诊断方法、治疗措施及效果,探讨适宜社区和基层的基本诊疗方法。方法:参考Irwin的慢性咳嗽解剖学诊断流程,对门诊120例慢性咳嗽患者的病因进行诊断分析,并按不同病因给予针对治疗。结果:120例慢性咳嗽患者中确诊109例,其中咳嗽变异型哮喘(CVA)31例;鼻后滴流综合征(PNDS)29例;感染后咳嗽(PIC)24例;胃食管反流性咳嗽(GERD)14例;血管紧张素转换酶抑制剂(ACEI)类药物诱导的药源性咳嗽11例。未明确病因11例。109例中103例咳嗽完全控制或治愈,6例明显缓解,有效率100%。结论:CVA、PNDS、PIC、GERD、ACEI类药物诱导性咳嗽等是慢性咳嗽的5个主要病因; Irwin的解剖学诊断流程是慢性咳嗽行之有效的程序化诊断方法。 展开更多
关键词 慢性咳嗽 病因 诊断 治疗
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人兽共患病病因浅析及其防治对策 被引量:3
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作者 宋杰 李琳 赵宝华 《中国兽药杂志》 2007年第3期47-50,共4页
人类传染病60%来源于动物,近年来禽流感、猪链球菌病的暴发直接威胁到了人类的健康和生命。本文通过对全球气候变暖、抗生素滥用、动物亚健康水平等病因以及发病趋势的分析,认为应健全法制、提高公民意识、加快科研速度、协调各方面的力... 人类传染病60%来源于动物,近年来禽流感、猪链球菌病的暴发直接威胁到了人类的健康和生命。本文通过对全球气候变暖、抗生素滥用、动物亚健康水平等病因以及发病趋势的分析,认为应健全法制、提高公民意识、加快科研速度、协调各方面的力量,以预防为主来防控人兽共患病的暴发。 展开更多
关键词 人兽共患病 病因 防治对策
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旅行者腹泻区域间病因学差异分析 被引量:3
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作者 秦佳 韩晓辉 +4 位作者 李俊 周启明 叶魏 张琳 章琪 《中国国境卫生检疫杂志》 CAS 2013年第6期391-395,共5页
目的比较旅行者腹泻(traveler’s diahrrea,TD)病原体的区域间差异,以期为预防和治疗提供依据。方法检索1973年至今发表于Pubmed(Medline)和中国知网的TD相关文献,对TD发生次数、人数、病原体、区域等因素进行整理及分析。结果经统计,... 目的比较旅行者腹泻(traveler’s diahrrea,TD)病原体的区域间差异,以期为预防和治疗提供依据。方法检索1973年至今发表于Pubmed(Medline)和中国知网的TD相关文献,对TD发生次数、人数、病原体、区域等因素进行整理及分析。结果经统计,肠产毒性大肠杆菌(Enterotoxic escherichia coli,ETEC)为最常见病原体,占总TD发病人数的30.86%(1 944/6 300),其中拉丁美洲、非洲和南亚阳性率最高,分别占该区域TD总数的33.59%(1 109/3 302)、31.22%(385/1233)和30.42%(223/733)。其余较高的病原体为肠黏附性大肠杆菌(Enteroadherent Escherichia coli,EAEC)和诺如病毒(Norovirus,NV)。ETEC、EAEC、肠致病性大肠杆菌(Enteropathogenic Escherichia coli,EPEC)、肠出血性大肠杆菌(Enterohemorrhagic Escherichia coli,EHEC)、弯曲杆菌、志贺氏菌、沙门氏菌、气单孢菌、毗邻单胞菌、非霍乱弧菌、贾第鞭毛虫、隐孢子虫、阿米巴原虫的感染均有地区间差异。结论TD的病原体存在地区间差异,了解该差异对TD的预防和治疗具有一定指导意义。 展开更多
关键词 旅行者腹泻 病原体 区域间 病因学 分析
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Microbiology of discharging ears in Ethiopia
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作者 Getachew Tesfaye Daniel Asrat +1 位作者 Yimtubezinash Woldeamanuel Messele Gizaw 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2009年第1期60-67,共8页
Objectives:To isolate and identify the bacterial etiologic agents,including their antibiotic susceptibility pattern isolated from patients with discharging ear infections.Methods:Between September 2006 and February 20... Objectives:To isolate and identify the bacterial etiologic agents,including their antibiotic susceptibility pattern isolated from patients with discharging ear infections.Methods:Between September 2006 and February 2007,178 patients with discharging ear visiting ENT clinics of St.Paul and Tikur Anbessa University Hospitals Addis Ababa,Ethiopia were investigated.Results:Of the patients investigated,52.8%were males and 47.2%were females resulting in an overall male to female ratio of 1.1:1.Ear discharge was the commonest clinical finding followed by hearing problem(91.2%),otalgia(ear pain)(74.7%),fever(17.9%) and itching of external ear(5.1%).S.aureus accounted for 30.2%of the total isolates followed by Proteus ssp. (P.mirabilis,P.vulgaris)(25.4%),and P.aeruginosa(13.4%).Both gram positive and negative bacteria isolated from ear infections showed low resistance rates to most antimicrobial agents tested.Overall ceftriaxone and ciprofloxacin were the most effective drugs when compared to other drugs tested against the grampositive and gram-negative bacteria.Conclusion:Otitis media was the most common clinical finding in patients with ear infection.With discharging ear,the gram-negative bacteria were the predominant isolates.The susceptibility pattern of isolates from the study showed that ceftriaxone,ciprofloxacin and gentamicin were the most effective drugs.It is recommended that treatment of ear infections should be based on culture and sensitivity at the study sites.Therefore,efforts should be directed towards early diagnosis and treatment of acute ear infection and continued re-evaluation of the resistant patterns of organisms to optimize treatments and reduce complications. 展开更多
关键词 OTITIS externa OTITIS media BACTERIAL etiologic agents Antibiotic SUSCEPTIBILITY pattern Ethiopia
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Understanding recurrent pregnancy loss:recent advances on its etiology,clinical diagnosis,and management 被引量:1
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作者 Chunwei Cao Shiyu Bai +3 位作者 Jing Zhang Xiaoyue Sun Anming Meng Hui Chen 《Medical Review》 2022年第6期570-589,共20页
Recurrent pregnancy loss(RPL)has become an important reproductive health issue worldwide.RPL affects about 2%–3%of reproductive-aged women,and makes serious threats to women’s physical and mental health.However,the ... Recurrent pregnancy loss(RPL)has become an important reproductive health issue worldwide.RPL affects about 2%–3%of reproductive-aged women,and makes serious threats to women’s physical and mental health.However,the etiology of approximately 50%of RPL cases remains unknown(unexplained RPL),which poses a big challenge for clinical management of these patients.RPL has been widely regarded as a complex disease where its etiology has been attributed to numerous factors.Heretofore,various risk factors for RPL have been identified,such as maternal ages,genetic factors,anatomical structural abnormalities,endocrine dysfunction,prethrombotic state,immunological factors,and infection.More importantly,development and applications of next generation sequencing technology have significantly expanded opportunities to discover chromosomal aberrations and single gene variants responsible for RPL,which provides new insight into its pathogenic mechanisms.Furthermore,based upon patients’diagnostic evaluation and etiologic diagnosis,specific therapeutic recommendations have been established.This review will highlight current understanding and recent advances on RPL,with a special focus on the immunological and genetic etiologies,clinical diagnosis and therapeutic management. 展开更多
关键词 etiologic diagnosis genetic etiology next generation sequencing recurrent pregnancy loss therapeutic recommendations
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北京市密云县病毒性肝炎病原学分型诊断调查 被引量:2
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作者 李立琴 王亚琼 王化勇 《首都公共卫生》 2009年第6期256-261,共6页
目的了解急性病毒性肝炎的分型诊断与疫情报告之间的差距,准确掌握北京市密云县各型病毒性肝炎发病情况的基线资料,为今后制定科学的防治策略提供科学依据。方法收集2005~2008年医疗机构网络直报的急性病毒性肝炎发病病例,对其进行流... 目的了解急性病毒性肝炎的分型诊断与疫情报告之间的差距,准确掌握北京市密云县各型病毒性肝炎发病情况的基线资料,为今后制定科学的防治策略提供科学依据。方法收集2005~2008年医疗机构网络直报的急性病毒性肝炎发病病例,对其进行流行病学调查或血清学检测。结果2005~2008年网报急性病毒性肝炎总例数为455例,核实确诊305例,符合率为67.03%。305例中甲型病毒性肝炎3例,占急性病毒性肝炎的0.98%;乙型病毒性肝炎161例,占52.79%;丙型病毒性肝炎27例,占8.85%;丁型病毒性肝炎1例,占0.33%,戊型病毒性肝炎58例,占19.02%;未分型肝炎55例,占18.03%。2005~2008年,密云县急性病毒性肝炎发病病例以乙型为主,甲型比例很小,但戊型肝炎的发病不容忽视。结论乙型肝炎、戊型肝炎应为当前病毒性肝炎防治重点;应进一步规范临床病毒性肝炎的诊断,同时继续定期开展病毒性肝炎的血清学监测。 展开更多
关键词 急性病毒性肝炎 分型诊断 流行病学 酶联免疫吸附试验
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昆明市妇幼保健院肠道病毒EV71疫苗接种后手足口病病原构成变化 被引量:2
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作者 李秀芳 王艳 +2 位作者 张倩 代大春 杨桂云 《云南医药》 2021年第5期421-423,426,共4页
目的通过观察疫苗接种前后我院手足口病病原构成变化,了解肠道病毒EV71疫苗接种后免疫保护情况,为肠道病毒EV71疫苗接种推广提供临床客观依据。方法以疫苗投入使用的2016年为分界点,选择昆明市妇幼保健院2014、2015年确诊为手足口病且... 目的通过观察疫苗接种前后我院手足口病病原构成变化,了解肠道病毒EV71疫苗接种后免疫保护情况,为肠道病毒EV71疫苗接种推广提供临床客观依据。方法以疫苗投入使用的2016年为分界点,选择昆明市妇幼保健院2014、2015年确诊为手足口病且已行病原学检查的患儿为对照组,2017、2018年确诊手足口病且行病原学检查患儿为观察组。比较2组肠道病毒EV71的感染率;同时把是否EV71感染作为因变量,是否接种疫苗,性别和年龄作为自变量进行多因素分析。结果男童观察组和对照组肠道病毒EV71感染率分别为2.1%、18%,2组之间存在统计学差异(χ2=21.269,P<0.05);女童观察组和对照组肠道病毒EV71感染率分别为0.9%、17.3%,2组之间差异有统计学意义(χ2=18.953,P<0.05)。观察组和对照组肠道病毒EV71感染率分别为1.6%、17.7%,2组之间差异有统计学意义(χ2=40.1,P<0.05)。多因素分析结果显示只有是否接种疫苗为影响因素,接种疫苗为保护因素,接种疫苗者感染EV71的可能性是不接种者的0.032倍。结论2016年接种肠道EV71灭活疫苗后,昆明市妇幼保健院就诊手足口病患儿中肠道病毒EV71病原构成比有下降,接种疫苗者感染EV71的可能性较不接种者小,疫苗接种对肠道病毒EV71感染引起的手足口病有很好的预防作用。 展开更多
关键词 手足口病 肠道病毒EV71 病原学 病原构成 感染率
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Discussing the Dietary Regimen and Disease Prevention and its Application as an Anti‑epidemic Measure 被引量:1
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作者 Jianhe Fang Weifeng Zhu Hongning Liu 《Chinese Medicine and Culture》 2020年第3期146-151,共6页
This article discusses the role of dietary regimen in the traditional culture of Chinese medicine according to its origin.Dietary regimen is a technique that inherits the traditional culture of Chinese medicine.Throug... This article discusses the role of dietary regimen in the traditional culture of Chinese medicine according to its origin.Dietary regimen is a technique that inherits the traditional culture of Chinese medicine.Through analysis of the characteristics of the dietary regimen and the discussion of the idea of disease prevention,the application of the dietary regimen in disease prevention is sought.Under the guidance of three key factors,the application of the dietary regimen in disease prevention is mainly manifested in two aspects.First,the dietary regimen can be used to guide the daily reasonable diet to maintain the human body in a balance of Yin and Yang,which could prevent the occurrence of diseases.Second,on the basis of minimizing health loss,it can be used for disease treatment,adjuvant treatment,and rehabilitation.Finally,taking preventive treatment as the guiding ideology,the application of a dietary regimen as an“anti‑epidemic”was briefly discussed. 展开更多
关键词 Anti‑epidemic dietary regimen disease prevention three categories of etiologic factors traditional culture of Chinese medicine
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昆明市妇幼保健院2014~2018年门急诊手足口病的病原构成变化 被引量:1
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作者 李秀芳 王艳 +2 位作者 刘春明 代大春 杨桂云 《昆明医科大学学报》 CAS 2021年第4期138-141,共4页
目的通过对昆明市妇幼保健院手足口病病原构成观察,了解肠道病毒EV71疫苗接种后免疫保护情况;为肠道病毒EV71疫苗接种推广提供临床客观依据。方法采集2014年1月至2018年12月间到昆明市妇幼保健院门急诊就诊临床确诊手足口病患儿的粪便标... 目的通过对昆明市妇幼保健院手足口病病原构成观察,了解肠道病毒EV71疫苗接种后免疫保护情况;为肠道病毒EV71疫苗接种推广提供临床客观依据。方法采集2014年1月至2018年12月间到昆明市妇幼保健院门急诊就诊临床确诊手足口病患儿的粪便标本,进行肠道病毒EV71,柯萨奇病毒A组16型,肠道病毒通用型PCR检测。按照是否接种肠道病毒EV71型灭活疫苗分为观察组和对照组。比较2组EV71及非EV71型病原构成比;同时把是否EV71感染作为因变量,是否接种疫苗,性别和年龄作为自变量进行多因素分析。结果观察组和对照组感染肠道病毒EV71构成比分别为0.6%、15%,2组之间存在差异(χ^(2)=27.088,P<0.05)。多因素分析结果显示只有是否接种疫苗为影响因素,接种疫苗为保护因素,接种疫苗者对EV71保护率达96.8%。结论昆明市妇幼保健院门急诊手足口病患儿中接种肠道病毒EV71灭活疫苗者感染肠道病毒EV71的构成比低于未接种者,推广疫苗接种对人群预防EV71感染引起的手足口病有很好的效果。 展开更多
关键词 手足口病 肠道病毒EV71 病原学 病原构成 构成比
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349例重型病毒性肝炎的临床特点及病毒标志物检测结果分析 被引量:1
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作者 徐爱华 徐学俊 《中国病原生物学杂志》 CSCD 2008年第6期459-461,共3页
目的了解重型病毒性肝炎住院病例的临床及病原学特点,探讨慢性肝炎重症化及其预后的关系。方法采用回顾性调查方法,对349例重型病毒性肝炎的临床特点及病毒标志物检测结果进行分析。结果349例重型病毒性肝炎患者中,发生于急性肝炎的28例... 目的了解重型病毒性肝炎住院病例的临床及病原学特点,探讨慢性肝炎重症化及其预后的关系。方法采用回顾性调查方法,对349例重型病毒性肝炎的临床特点及病毒标志物检测结果进行分析。结果349例重型病毒性肝炎患者中,发生于急性肝炎的28例,发生于慢性肝炎有明确肝病史和无明确肝病史的分别为245例和76例;引起重型肝炎的病毒中以HBV单一或重叠感染率最高,占82.2%(287/349),6例(1.72%)未能确定病原,未发现单一HAV、HDV和HGV感染者,HBV重叠HEV感染者病死率为65.2%(15/23),HEV重叠其他肝炎病毒感染者的病死率为60%(18/30),均比单一HBV或单一HEV感染者高(P<0.01和P<0.05)。结论重型肝炎仍以HBV感染为主,HBV和HEV重叠感染可以加重病情、病死率高。 展开更多
关键词 重型病毒性肝炎 病原学 临床特点 重叠感染
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The application of the “Treatment in Accordance with Three Categories of Etiologic Factors” theory in the prevention and treatment of epidemic diseases in traditional Chinese medicine since the Ming and Qing Dynasties
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作者 Bo-Yang Zhang 《Medical Theory and Hypothesis》 2022年第4期20-26,共7页
“Treatment in accordance with three categories of etiologic factors”(consideration of the climatic and seasonal conditions,environment and individual’s constitution in the treatment of diseases),that is,treatment f... “Treatment in accordance with three categories of etiologic factors”(consideration of the climatic and seasonal conditions,environment and individual’s constitution in the treatment of diseases),that is,treatment following time,place and individual,is one of the basic principles followed by Chinese medicine in the clinical treatment of diseases.This paper analyzes the similarities and differences in traditional Chinese medicine treatment of patients with epidemic diseases in different regions and periods since the Ming(1368-1644 C.E.)and Qing(1636-1912 C.E.)Dynasties.In addition,the theory of epidemic disease prevention and control based on the application of“treatment in accordance with three categories of etiologic factors”was discussed to inspire and guide the prevention and treatment of COVID-19. 展开更多
关键词 traditional Chinese medicine treatment in accordance with three categories of etiologic factors epidemic diseases COVID-19
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吉兰-巴雷综合征合并肺炎相关危险因素及病原学特点
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作者 许晓辉 马聪敏 韩月珍 《武汉大学学报(医学版)》 CAS 2015年第5期739-742,共4页
目的:探讨吉兰-巴雷综合征(GBS)相关性肺炎的危险因素及病原学特点。方法:收集160例GBS合并肺炎患者(观察组)及164例无肺炎的GBS患者(对照组)的临床资料,分析GBS合并肺炎的危险因素。结果:GBS合并肺炎组中年龄、变异型GBS、慢性阻塞性... 目的:探讨吉兰-巴雷综合征(GBS)相关性肺炎的危险因素及病原学特点。方法:收集160例GBS合并肺炎患者(观察组)及164例无肺炎的GBS患者(对照组)的临床资料,分析GBS合并肺炎的危险因素。结果:GBS合并肺炎组中年龄、变异型GBS、慢性阻塞性肺病、吞咽困难、气管切开、使用呼吸机、使用质子泵抑制剂、未应用免疫球蛋白、肌电图有脱髓鞘合并轴索损伤表现、住院天数均高于对照组(P<0.05),Logistic回归分析表明年龄、变异型GBS、慢性阻塞性肺病、吞咽困难、气管切开、使用呼吸机、使用质子泵抑制剂、未应用免疫球蛋白是GBS合并肺炎的独立危险因素(P<0.05)。共检出有效菌株124株,其中革兰阴性杆菌71.8%,革兰阳性球菌28.2%。结论:年龄、变异型GBS、慢性阻塞性肺病、吞咽困难、气管切开、使用呼吸机、使用质子泵抑制剂、未应用免疫球蛋白是GBS合并肺炎的独立危险因素,GBS合并肺炎患者的主要致病菌为革兰阴性杆菌。 展开更多
关键词 吉兰-巴雷综合征 肺炎 危险因素 病原学
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Discussing the Dietary Regimen and Disease Prevention and its Application as an Anti-epidemic Measure
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作者 Jianhe Fang Weifeng Zhu Hongning Liu 《Chinese Medicine and Culture》 2019年第1期146-151,共6页
This article discusses the role of dietary regimen in the traditional culture of Chinese medicine according to its origin.Dietary regimen is a technique that inherits die traditional culture of Chinese medicine.Throug... This article discusses the role of dietary regimen in the traditional culture of Chinese medicine according to its origin.Dietary regimen is a technique that inherits die traditional culture of Chinese medicine.Through analysis of the characteristics of the dietary regimen and the discussion of the idea of disease prevention,the application of the dietary regimen in disease prevention is sought.Under the guidance of three key factors,the application of the dietary regimen in disease prevention is mainly manifested in two aspects,h irst,the dietary regimen can be used to guide the daily reasonable diet to maintain the human body in a balance of Yin and Yang,which could prevent the occurrence of diseases.Second,on the basis of minimizing health loss,it can be used for disease treatment,adjuvant treatment,and rehabilitation.Finally,taking preventive treatment as the guiding ideology,the application of a dietary regimen as an"anti-epidemic"was briefly discussed. 展开更多
关键词 Anti-epidemic dietary regimen disease prevention three categories of etiologic factors traditional culture of Chinese medicine
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一起鼠伤寒沙门菌食物中毒的病原学检测与溯源分析
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作者 徐兰 钱惠芬 +4 位作者 吴鹏程 施菊萍 施爱萍 樊飞 刘芳 《医学动物防制》 2021年第5期434-437,共4页
目的对一起由鼠伤寒沙门菌引起的食物中毒进行病原学检测与溯源分析。方法将采集的样本先用实时荧光定量PCR(real-time fluorescent quantitative PCR,RT-PCR)进行初步检测,然后按常规进行病原菌的分离培养、生化鉴定、血清型分型和药... 目的对一起由鼠伤寒沙门菌引起的食物中毒进行病原学检测与溯源分析。方法将采集的样本先用实时荧光定量PCR(real-time fluorescent quantitative PCR,RT-PCR)进行初步检测,然后按常规进行病原菌的分离培养、生化鉴定、血清型分型和药敏试验,用脉冲场凝胶电泳(pulsed-field gel electrophoresis,PFGE)对分离出的沙门菌菌株进行同源性分析。结果11份肛拭子样本中有5份检出鼠伤寒沙门菌,5份食品样本中有2份检出鼠伤寒沙门菌,7株鼠伤寒沙门菌均对头孢唑林、头孢替坦、阿米卡星、庆大霉素和妥布霉素耐药,其中有5株对呋喃妥因中度敏感。运用PFGE对分离到的鼠伤寒沙门菌进行分子分型,其图谱相似性系数为85.29%~100.00%。结论本次食物中毒是由进食被鼠伤寒沙门菌污染的皮蛋和炒小瓜所致,通过PFGE对致病菌进行溯源,追踪菌株的来源,PFGE能有效应用于食物中毒溯源分析。 展开更多
关键词 鼠伤寒沙门菌 食物中毒 脉冲场凝胶电泳 病原学 分析
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Clinical and microbiological features of vulvovaginitis in Mexican girls
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作者 Mario I.Ortiz Edna J.Arreola-Bautista +2 位作者 Beatriz A.Sánchez-Reyes Georgina Romo-Hernández Marco A.Escamilla-Acosta 《Open Journal of Obstetrics and Gynecology》 2013年第2期243-248,共6页
Study Objective: To determine the prevalence of vulvovaginitis, predisposing factors, microbial etiology and therapy in patients treated at the Hospital del Nino DIF, Pachuca, Hidalgo, Mexico. Design. This was an obse... Study Objective: To determine the prevalence of vulvovaginitis, predisposing factors, microbial etiology and therapy in patients treated at the Hospital del Nino DIF, Pachuca, Hidalgo, Mexico. Design. This was an observational and descriptive study from 2006 to 2009. Setting: Hospital del Nino DIF, Pachuca, Hidalgo, Mexico. Participants. Patients from 0 to 16 years, with vulvovaginitis and/or vaginal discharge were included. Interventions: None. Main Outcome Measures: Demographic data, etiology, clinical features, risk factors and therapy were analyzed. Results: Four hundred twenty seven patients with diagnosis of vulvovaginitis were included. The average prevalence to 4 years in the study period was 0.19%. The age group most affected was schoolchildren (225 cases: 52.69%). The main signs and symptoms presented were leucorrhea (99.3%), vaginal hyperemia (32.6%), vulvar itching (32.1%) and erythema (28.8%). Identified risk factors were poor hygiene (15.7%), urinary tract infection (14.7%), intestinal parasites (5.6%) and obesity or overweight (3.3%). The main microorganisms found in vaginal cultures were enterobacteriaceae (Escherichia coli, Klebsiella and Enterococcus faecalis), Staphylococcus spp, and Gardnerella vaginalis. Several inconsistent were found in the drug prescription of the patients. Conclusion: Vulvovaginitis prevalence in Mexican girls is low and this was caused mainly by opportunist microorganisms. The initial treatment of vulvovaginitis must include hygienic measure and an antimicrobial according to the clinical features and microorganism found. 展开更多
关键词 VULVOVAGINITIS PREVALENCE etiologic Microorganisms Mexican Children and Adolescents
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各地区中医药预防新型冠状病毒肺炎(COVID-19)方案分析 被引量:125
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作者 徐旭 张莹 +1 位作者 李新 李晓霞 《中草药》 CAS CSCD 北大核心 2020年第4期866-872,共7页
分析湖北省武汉市新型冠状病毒肺炎(COVID-19)疫情蔓延后各地区发布的中医药预防方案,探究其规律,更好地指导临床用药。收集互联网上发布的新闻和通报,自2019年12月8日官方通报的武汉首例不明原因肺炎发病病例至2020年2月1日北京、天津... 分析湖北省武汉市新型冠状病毒肺炎(COVID-19)疫情蔓延后各地区发布的中医药预防方案,探究其规律,更好地指导临床用药。收集互联网上发布的新闻和通报,自2019年12月8日官方通报的武汉首例不明原因肺炎发病病例至2020年2月1日北京、天津等地区的13项含中药处方的中医药预防COVID-19的方案。13项预防方案中多用黄芪、玉屏风散等中药和方剂补"正气";由于疫情发于冬季,预防方案体现因时制宜的原则;北方8个地区多使用麦冬、玄参等滋阴润燥中药,南方5个地区多用苍术、藿香等芳香除湿中药,预防方案体现因地制宜的原则;根据人群体质不同采用不同处方,体现因人制宜的原则。此外,还应重视隔离病原、起居有节、调节情志、饮食营养、适当运动等预防措施。COVID-19的中医药预防应注重补正气,根据不同气候、不同地区、不同人群辨证用药,重视综合预防,灵活运用各种措施,达到最佳预防效果。 展开更多
关键词 新型冠状病毒肺炎 中医药 预防方案分析 补正气 三因制宜
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