Naturally occurring cembrene-C (1) has been synthesized from geraniol. The key steps were coupling reaction of the sulphone (6) and chloride (8) and selective cyclization of dicarbonyl compound (12) catalyzed by low v...Naturally occurring cembrene-C (1) has been synthesized from geraniol. The key steps were coupling reaction of the sulphone (6) and chloride (8) and selective cyclization of dicarbonyl compound (12) catalyzed by low valent titanium.展开更多
Three new naphthaline-type chromophores end-capped with different (p-substituted amino) styryl groups on the both sides (named as BPASN, BHMASN and BMASN) have been synthesized. Under excitation of 380 nm, strong gree...Three new naphthaline-type chromophores end-capped with different (p-substituted amino) styryl groups on the both sides (named as BPASN, BHMASN and BMASN) have been synthesized. Under excitation of 380 nm, strong green light-emitting locating at 517 nm with the fluorescence quantum yield of 0.88 in CH2Cl2 has been obtained. In the presence of b-cyclodextrin (b-CD), strong blue-emitting at 456 nm in DMF was also recorded.展开更多
2-Phenyl-3-thioformylindolizine and 1,2-dimethyl-3-thioformylindolizine undergo a novel desulfur coupling reaction in the presence of tributylphosphine to give （E）-1,2-bis（3-indolizinyl）ethenes in high yields. The...2-Phenyl-3-thioformylindolizine and 1,2-dimethyl-3-thioformylindolizine undergo a novel desulfur coupling reaction in the presence of tributylphosphine to give （E）-1,2-bis（3-indolizinyl）ethenes in high yields. The structures of products were confirmed by IR, ^1H NMR, MS, elemental analysis and single crystal X-ray diffraction analysis. The mechanisms involved in various stages of the reaction were discussed.展开更多
目的:优化8-氯-5,10-二氢-11H-二苯并[b,e][1,4]-二氮-11-酮的制备工艺。方法:重结晶提纯化合物,依据HPLC分析的结果,利用正交试验法,以反应时间、二甲苯用量、多聚磷酸用量和干燥温度作为影响因素,考查其对制备工艺优化的影响。结果:...目的:优化8-氯-5,10-二氢-11H-二苯并[b,e][1,4]-二氮-11-酮的制备工艺。方法:重结晶提纯化合物,依据HPLC分析的结果,利用正交试验法,以反应时间、二甲苯用量、多聚磷酸用量和干燥温度作为影响因素,考查其对制备工艺优化的影响。结果:确立了最优的工艺配方为反应时间21 h,二甲苯用量450 m L,多聚磷酸用量3 m L和干燥温度20℃。结论:经过多次试验证实,通过本文的试验方法制备8-氯-5,10-二氢-11H-二苯并[b,e][1,4]-二氮-11-酮的收率和纯度比文献工艺有了明显的提升,效果显著。展开更多
基金Project supported by the National Natural Science Foundation of China and by the Special Research Grant for Doctoral Sites in Universities
文摘Naturally occurring cembrene-C (1) has been synthesized from geraniol. The key steps were coupling reaction of the sulphone (6) and chloride (8) and selective cyclization of dicarbonyl compound (12) catalyzed by low valent titanium.
文摘Three new naphthaline-type chromophores end-capped with different (p-substituted amino) styryl groups on the both sides (named as BPASN, BHMASN and BMASN) have been synthesized. Under excitation of 380 nm, strong green light-emitting locating at 517 nm with the fluorescence quantum yield of 0.88 in CH2Cl2 has been obtained. In the presence of b-cyclodextrin (b-CD), strong blue-emitting at 456 nm in DMF was also recorded.
基金Project supported by the National Natural Science Foundation of China （No. 20672090）, the Natural Science Foundation of Jiangsu Education Department （No. 06KJD150015）, the Key Laboratory of Marine Biotechnology Foundation of Jiangsu Province （No. 2006HS014） and the Hualhai Institute of Technology Disciplinary Construction Foundation （No. XK200309）.
文摘2-Phenyl-3-thioformylindolizine and 1,2-dimethyl-3-thioformylindolizine undergo a novel desulfur coupling reaction in the presence of tributylphosphine to give （E）-1,2-bis（3-indolizinyl）ethenes in high yields. The structures of products were confirmed by IR, ^1H NMR, MS, elemental analysis and single crystal X-ray diffraction analysis. The mechanisms involved in various stages of the reaction were discussed.
文摘目的:优化8-氯-5,10-二氢-11H-二苯并[b,e][1,4]-二氮-11-酮的制备工艺。方法:重结晶提纯化合物,依据HPLC分析的结果,利用正交试验法,以反应时间、二甲苯用量、多聚磷酸用量和干燥温度作为影响因素,考查其对制备工艺优化的影响。结果:确立了最优的工艺配方为反应时间21 h,二甲苯用量450 m L,多聚磷酸用量3 m L和干燥温度20℃。结论:经过多次试验证实,通过本文的试验方法制备8-氯-5,10-二氢-11H-二苯并[b,e][1,4]-二氮-11-酮的收率和纯度比文献工艺有了明显的提升,效果显著。
