Background There is a paucity of studies conducted in India on neonatal outcomes of preterm birth and low birth weight.Hence,we aimed to assess the impact of preterm birth and low birth weight on medical conditions,me...Background There is a paucity of studies conducted in India on neonatal outcomes of preterm birth and low birth weight.Hence,we aimed to assess the impact of preterm birth and low birth weight on medical conditions,medication use and mortality among neonates.Methods A prospective observational cohort study was conducted at the neonatal intensive care unit (NICU) over a period of 9 months.Neonates of either sex,admitted to NICU and who received at least one medication were enrolled in the study.Perinatal and demographic data,reason(s) for NICU admission,diagnoses,medications prescribed,medication-related problems,discharge status and the direct medical cost were documented and analyzed.Results Four hundred and five neonates Were included in the study:60.5% were boys,32.7% were preterm and 44.2% were born underweight.Neonatal sepsis (n =125,16.7%),unconjugated hyperbilirubinemia (n =83,11.1%) and respiratory distress syndrome (n =62,8.3%) were the most common medical conditions and were significantly more common among preterm and underweight neonates.Nearly half of the medications prescribed were anti-infectives for systemic use (n =1310,47.4%).The mean number of medications received by neonates increased from term to extremely preterm (5.2-15.0) and normal birth weight to extremely low birth weight (5.0-14.9).Mortality rate was significantly higher among extremely preterm (66.7%),and very preterm (15.2%) neonates compared to term (2.9%) neonates.The median direct medical cost for NICU admission was INR 21,430 (USD 331).Conclusion Medical conditions,medications prescribed and mortality rate were significantly higher among preterm and underweight neonates admitted to NICU.展开更多
Information was obtained from the same questionnaire (23 risk factors listed) of cases and controls. We used a multivariate logistic model, which described variables significantly increased risk of birth defects....Information was obtained from the same questionnaire (23 risk factors listed) of cases and controls. We used a multivariate logistic model, which described variables significantly increased risk of birth defects. The risk factors included maternal educational levels, medicine taken during pregnancy and antenatal care. It was suggested to strengthen antenatal care was the main preventive measure against birth defects.展开更多
文摘Background There is a paucity of studies conducted in India on neonatal outcomes of preterm birth and low birth weight.Hence,we aimed to assess the impact of preterm birth and low birth weight on medical conditions,medication use and mortality among neonates.Methods A prospective observational cohort study was conducted at the neonatal intensive care unit (NICU) over a period of 9 months.Neonates of either sex,admitted to NICU and who received at least one medication were enrolled in the study.Perinatal and demographic data,reason(s) for NICU admission,diagnoses,medications prescribed,medication-related problems,discharge status and the direct medical cost were documented and analyzed.Results Four hundred and five neonates Were included in the study:60.5% were boys,32.7% were preterm and 44.2% were born underweight.Neonatal sepsis (n =125,16.7%),unconjugated hyperbilirubinemia (n =83,11.1%) and respiratory distress syndrome (n =62,8.3%) were the most common medical conditions and were significantly more common among preterm and underweight neonates.Nearly half of the medications prescribed were anti-infectives for systemic use (n =1310,47.4%).The mean number of medications received by neonates increased from term to extremely preterm (5.2-15.0) and normal birth weight to extremely low birth weight (5.0-14.9).Mortality rate was significantly higher among extremely preterm (66.7%),and very preterm (15.2%) neonates compared to term (2.9%) neonates.The median direct medical cost for NICU admission was INR 21,430 (USD 331).Conclusion Medical conditions,medications prescribed and mortality rate were significantly higher among preterm and underweight neonates admitted to NICU.
文摘Information was obtained from the same questionnaire (23 risk factors listed) of cases and controls. We used a multivariate logistic model, which described variables significantly increased risk of birth defects. The risk factors included maternal educational levels, medicine taken during pregnancy and antenatal care. It was suggested to strengthen antenatal care was the main preventive measure against birth defects.
