Objective: To observe the effects of the drugs for supplementing Qi and nourishing Yin, promoting blood circulation to remove blood stasis on insulin resistance in type 2 diabetes. Methods: 89 patients of type 2 diabe...Objective: To observe the effects of the drugs for supplementing Qi and nourishing Yin, promoting blood circulation to remove blood stasis on insulin resistance in type 2 diabetes. Methods: 89 patients of type 2 diabetes treated with the Suifonylureas and the Biguanides were divided into treatment group (59 cases) and control group (30 cases). The treatment group were treated with the drugs for supplementing Qi and nourishing Yin, promoting blood circulation to remove blood stasis. Before and after the treatment, fasting plasma glucose and insulin (FPG and FINS ), insulin action index (IAI) were determined. Results: After the treatment, the level of FPG was decreased, the level of IAI was increased, the difference of FINS was not significant in the treatment group. Conclusions: The drugs for supplementing Qi and nourishing Yin, promoting blood circulation to remove blood stasis may improve insulin resistance to decrease FPG.展开更多
目的探讨基于三证三法辨证原则及菌毒炎并治理论采用血必净注射液联合西药常规治疗重症肺炎并脓毒症的临床疗效。方法选取2019年1月—2020年12月期间安庆市立医院收治的重症肺炎合并脓毒症患者84例,按随机数字表法分为对照组和治疗组,...目的探讨基于三证三法辨证原则及菌毒炎并治理论采用血必净注射液联合西药常规治疗重症肺炎并脓毒症的临床疗效。方法选取2019年1月—2020年12月期间安庆市立医院收治的重症肺炎合并脓毒症患者84例,按随机数字表法分为对照组和治疗组,各42例。对照组给予常规治疗,治疗组在对照组基础上给予血必净注射液治疗。两组患者均连续治疗10 d后,观察比较两组患者治疗后临床疗效、细菌清除率,以及治疗前后生命体征(呼吸、心率、体温、白细胞)、血气状态[血液酸碱度(Potential of hydrogen,pH)、血氧分压(Partial pressure of oxygen,PaO_(2))、二氧化碳分压(Arterial partial pressure of carbon dioxide,PaCO_(2))]、炎症感染指标[白细胞介素-6(Interleukin-6,IL-6)、肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)、降钙素原(Procalcitonin,PCT)、C反应蛋白(C-reactive protein,CRP)]。记录治疗期间不良反应发生情况。结果治疗后治疗组总有效率为92.86%(39/42)明显高于对照组73.17%(30/41),差异有统计学意义(P<0.05)。治疗后治疗组细菌清除率为90.48%(38/42)明显高于对照组68.29%(28/41),差异有统计学意义(P<0.05)。治疗后两组患者呼吸、心率、体温、白细胞值及血清IL-6、TNF-α、PCT、CRP水平均低于治疗前,差异有统计学意义(P<0.05);且治疗组呼吸、心率、体温、白细胞值及血清IL-6、TNF-α、PCT、CRP水平均低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者血液pH值、PaCO_(2)均低于治疗前,PaO_(2)均高于治疗前,差异有统计学意义(P<0.05);且治疗组血液pH值、PaCO_(2)均低于对照组,PaO_(2)高于对照组,差异有统计学意义(P<0.05)。治疗期间,两组患者不良反应总发生率比较,差异无统计学意义(P>0.05)。结论基于三证三法辨证原则及菌毒炎并治理论,采用血必净注射液治疗重症肺炎合并脓毒症患者可显著提高临床疗效和细菌清除率,促进患�展开更多
文摘Objective: To observe the effects of the drugs for supplementing Qi and nourishing Yin, promoting blood circulation to remove blood stasis on insulin resistance in type 2 diabetes. Methods: 89 patients of type 2 diabetes treated with the Suifonylureas and the Biguanides were divided into treatment group (59 cases) and control group (30 cases). The treatment group were treated with the drugs for supplementing Qi and nourishing Yin, promoting blood circulation to remove blood stasis. Before and after the treatment, fasting plasma glucose and insulin (FPG and FINS ), insulin action index (IAI) were determined. Results: After the treatment, the level of FPG was decreased, the level of IAI was increased, the difference of FINS was not significant in the treatment group. Conclusions: The drugs for supplementing Qi and nourishing Yin, promoting blood circulation to remove blood stasis may improve insulin resistance to decrease FPG.
文摘目的探讨基于三证三法辨证原则及菌毒炎并治理论采用血必净注射液联合西药常规治疗重症肺炎并脓毒症的临床疗效。方法选取2019年1月—2020年12月期间安庆市立医院收治的重症肺炎合并脓毒症患者84例,按随机数字表法分为对照组和治疗组,各42例。对照组给予常规治疗,治疗组在对照组基础上给予血必净注射液治疗。两组患者均连续治疗10 d后,观察比较两组患者治疗后临床疗效、细菌清除率,以及治疗前后生命体征(呼吸、心率、体温、白细胞)、血气状态[血液酸碱度(Potential of hydrogen,pH)、血氧分压(Partial pressure of oxygen,PaO_(2))、二氧化碳分压(Arterial partial pressure of carbon dioxide,PaCO_(2))]、炎症感染指标[白细胞介素-6(Interleukin-6,IL-6)、肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)、降钙素原(Procalcitonin,PCT)、C反应蛋白(C-reactive protein,CRP)]。记录治疗期间不良反应发生情况。结果治疗后治疗组总有效率为92.86%(39/42)明显高于对照组73.17%(30/41),差异有统计学意义(P<0.05)。治疗后治疗组细菌清除率为90.48%(38/42)明显高于对照组68.29%(28/41),差异有统计学意义(P<0.05)。治疗后两组患者呼吸、心率、体温、白细胞值及血清IL-6、TNF-α、PCT、CRP水平均低于治疗前,差异有统计学意义(P<0.05);且治疗组呼吸、心率、体温、白细胞值及血清IL-6、TNF-α、PCT、CRP水平均低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者血液pH值、PaCO_(2)均低于治疗前,PaO_(2)均高于治疗前,差异有统计学意义(P<0.05);且治疗组血液pH值、PaCO_(2)均低于对照组,PaO_(2)高于对照组,差异有统计学意义(P<0.05)。治疗期间,两组患者不良反应总发生率比较,差异无统计学意义(P>0.05)。结论基于三证三法辨证原则及菌毒炎并治理论,采用血必净注射液治疗重症肺炎合并脓毒症患者可显著提高临床疗效和细菌清除率,促进患�
