Three new phenanthrenes,along with one known phenanthrene,were isolated from the ethanolic extract of the tubers of Cremastra appendiculata（D.Don） Makino.Their structures were elucidated on the basis of extensive sp...Three new phenanthrenes,along with one known phenanthrene,were isolated from the ethanolic extract of the tubers of Cremastra appendiculata（D.Don） Makino.Their structures were elucidated on the basis of extensive spectroscopic analysis.Compounds 1-4 were tested for in vitro cytotoxic activities against human lung（A549）,colon（HCT-116）,liver（HepG2）,and breast（MCF-7 and MDA-MB-231） cancer cell lines.展开更多
Shan Ci Gu(山慈菇Pseudobulbus Cremastrae seu Pleiones),a rare and precious traditional Chinese medicine,has attracted attention for the treatment of various cancers and bacterial infections.According to the Pharmacopo...Shan Ci Gu(山慈菇Pseudobulbus Cremastrae seu Pleiones),a rare and precious traditional Chinese medicine,has attracted attention for the treatment of various cancers and bacterial infections.According to the Pharmacopoeia of the People's Republic of China,Pseudobulbus Cremastrae seu Pleionesis sourced from the pseudobulbs of three plants in the Orchidaceae family:Cremastra appendiculata(D.Don)Makino,Pleione bulbocodioides(Franch.)Rolfe,and Pleione yunnanensis Rolfe.Extracts from Pseudobulbus Cremastrae seu Pleiones are used for the treatment of tumors,burns,and frostbite.The aims of this review are to provide information on the historical and herbological origins of Pseudobulbus Cremastrae seu Pleiones,to summarize research conducted on its phytochemical and biological activities over the last twenty years,and to detail planting efforts.展开更多
基金supported by National Key Technology R&D Program "New Drug Innovation" of China(Nos. 2012ZX09301002-002-002 and 2012ZX09304-005)
文摘Three new phenanthrenes,along with one known phenanthrene,were isolated from the ethanolic extract of the tubers of Cremastra appendiculata（D.Don） Makino.Their structures were elucidated on the basis of extensive spectroscopic analysis.Compounds 1-4 were tested for in vitro cytotoxic activities against human lung（A549）,colon（HCT-116）,liver（HepG2）,and breast（MCF-7 and MDA-MB-231） cancer cell lines.
基金This project was supported by the Special Fund of the Guangxi Zhuang Autonomous Region for Specially-invited Experts of China(No.2019B24).
文摘Shan Ci Gu(山慈菇Pseudobulbus Cremastrae seu Pleiones),a rare and precious traditional Chinese medicine,has attracted attention for the treatment of various cancers and bacterial infections.According to the Pharmacopoeia of the People's Republic of China,Pseudobulbus Cremastrae seu Pleionesis sourced from the pseudobulbs of three plants in the Orchidaceae family:Cremastra appendiculata(D.Don)Makino,Pleione bulbocodioides(Franch.)Rolfe,and Pleione yunnanensis Rolfe.Extracts from Pseudobulbus Cremastrae seu Pleiones are used for the treatment of tumors,burns,and frostbite.The aims of this review are to provide information on the historical and herbological origins of Pseudobulbus Cremastrae seu Pleiones,to summarize research conducted on its phytochemical and biological activities over the last twenty years,and to detail planting efforts.
