Tuberculosis(TB) involving the pancreas are uncommon, especially when present in immunocompetent hosts. Pancreatic TB is more frequently associated with miliary TB or widely disseminated disease. Pancreatic TB may pre...Tuberculosis(TB) involving the pancreas are uncommon, especially when present in immunocompetent hosts. Pancreatic TB is more frequently associated with miliary TB or widely disseminated disease. Pancreatic TB may present as cystic or solid pancreatic masses, pancreatic abscess or acute or chronic pancreatitis. Majority of the cases are diagnosed after surgical exploration for presumed pancreatic malignancy and preoperative diagnosis is quite difficult. However, improvement in imaging techniques and the resulting imageguided interventions gradually can obviate the need for more invasive diagnostic surgical procedures and expedite the planning of therapy. Herein, we report a rare case of isolated pancreatic TB which presented with pancreatic mass lesion in an immunocompetent host. Diagnosis was made by contrast enhanced computed tomography and guided fine needle aspiration of the pancreatic mass which revealed acid-fast bacillion Ziehl-Neelsen stain. The case was treated successfully with antituberculous drugs. Pancreatic tuberculosis should be considered in the differential diagnosis of a pancreatic mass when the patient is young, residing in the endemic zone of tuberculosis. Every attempt should be made to diagnose the cases to prevent unnecessary operation.展开更多
介绍近年的新型抗结核药物及其发展情况。以"抗结核新药""Tuberculosis new drug"等为关键词,分别查询2010年1月至2016年8月PubMed、维普中文科技期刊数据库等中有关抗结核新药的研究文献及其作用特点进行综述。文...介绍近年的新型抗结核药物及其发展情况。以"抗结核新药""Tuberculosis new drug"等为关键词,分别查询2010年1月至2016年8月PubMed、维普中文科技期刊数据库等中有关抗结核新药的研究文献及其作用特点进行综述。文章中会依次介绍受人瞩目的呗达喹啉等抗结核药物。此类药物不仅在肺结核的治疗上,同时也在治疗多重耐药、广泛耐药结核菌上提供了可能。展开更多
文摘Tuberculosis(TB) involving the pancreas are uncommon, especially when present in immunocompetent hosts. Pancreatic TB is more frequently associated with miliary TB or widely disseminated disease. Pancreatic TB may present as cystic or solid pancreatic masses, pancreatic abscess or acute or chronic pancreatitis. Majority of the cases are diagnosed after surgical exploration for presumed pancreatic malignancy and preoperative diagnosis is quite difficult. However, improvement in imaging techniques and the resulting imageguided interventions gradually can obviate the need for more invasive diagnostic surgical procedures and expedite the planning of therapy. Herein, we report a rare case of isolated pancreatic TB which presented with pancreatic mass lesion in an immunocompetent host. Diagnosis was made by contrast enhanced computed tomography and guided fine needle aspiration of the pancreatic mass which revealed acid-fast bacillion Ziehl-Neelsen stain. The case was treated successfully with antituberculous drugs. Pancreatic tuberculosis should be considered in the differential diagnosis of a pancreatic mass when the patient is young, residing in the endemic zone of tuberculosis. Every attempt should be made to diagnose the cases to prevent unnecessary operation.
文摘介绍近年的新型抗结核药物及其发展情况。以"抗结核新药""Tuberculosis new drug"等为关键词,分别查询2010年1月至2016年8月PubMed、维普中文科技期刊数据库等中有关抗结核新药的研究文献及其作用特点进行综述。文章中会依次介绍受人瞩目的呗达喹啉等抗结核药物。此类药物不仅在肺结核的治疗上,同时也在治疗多重耐药、广泛耐药结核菌上提供了可能。
