To evaluate the value of 16-slice spiral CT in the demonstration of coronary artery and in the diagnose of coronary artery stenosis. Methods Plain and enhanced CT scans were performed with a 16-slice CT scanner (Sensa...To evaluate the value of 16-slice spiral CT in the demonstration of coronary artery and in the diagnose of coronary artery stenosis. Methods Plain and enhanced CT scans were performed with a 16-slice CT scanner (Sensation 16, Siemens, Germany) in 230 patients with suspected coronary heart disease (CHD). Parameters of the plain scan were: 120 kV, 133 mA, slice col-limation 16 mm×1.5 mm, rotation time 0.42 seconds, increment 1.5 mm, and slice width 3 mm. Parameters of the enhanced scan were: 120 kV, 500 mA, slice collimation 16 mm×0.75 mm, rotation time 0.42 seconds, increment 0.5 mm, and slice width 1 mm. Enhanced CT scan was performed with a rapid intravenous injection of 100 mL iothalamate meglumine (Ultravist) (370 mgI/mL) or Omnipaque (350 mgI/mL) and 30 mL 0.9% NaCl chaser bolus at a flow rate of 3.5 mL/s. Calcium scoring with plain scan images and two and three dimensional reconstruction with enhanced scan images were made in all cases, among which 30 cases underwent conventional coronary angiography. Demonstration of coronary arteries and their stenosis were evaluated and the factors that might influence the image quality were analyzed. Results Coronary calcium scores were calculated and coronary artery was demonstrated in our study. In the evaluationof image quality with volume rendering technique (VRT) images, 78.3% of the images were of the first class, 12.2% the sec-ond class, and 9.6% the third class. Multi-planar reconstruction (MPR) and maximal intensity projection (MIP) were better than VRT in the demonstration of small branches. The image quality was related to the heart rate, with or without arrhythmia, and breath-hold ability of patients. Comparative study of the stenosis of coronary arteries in 30 cases showed that the sensi-tivity and specificity of 16-slice coronary CT angiography (CTA) to diagnose significant stenosis were 95.8% and 94.8% resp-ectively. Conclusion As a non-invasive and quick method, 16-slice coronary CTA is sensitive and specific to diagnose the stenosis of coronary arterie展开更多
目的汇总磁共振成像(MRI)辅助钼靶对致密型乳腺女性进行乳腺癌筛查的灵敏度、特异度及阳性预测值。方法检索PubMed、Web of Science、Embase、中国知网和万方数据库获取2021-09-30之前发表的相关文献。文献入选标准:(1)研究对象为致密...目的汇总磁共振成像(MRI)辅助钼靶对致密型乳腺女性进行乳腺癌筛查的灵敏度、特异度及阳性预测值。方法检索PubMed、Web of Science、Embase、中国知网和万方数据库获取2021-09-30之前发表的相关文献。文献入选标准:(1)研究对象为致密型乳腺女性;(2)研究类型为观察性研究或干预性研究;(3)研究报告了钼靶联合MRI或钼靶阴性之后再行MRI筛查乳腺癌的灵敏度、特异度或阳性预测值。排除标准:(1)文献类型为综述、会议摘要、评论或社论等;(2)不能获取原文;(3)未报告准确性相关指标或阳性预测值且未提供基础数据。采用诊断试验质量评价工具诊断准确性研究质量评价标准-2(quality assessment of diagnostic accuracy studies-2,QUADAS-2)围绕病例选择、待评价的诊断试验、金标准等领域从研究偏倚与临床适用性2个维度评价文献质量,评价结果分为高风险、低风险和风险不详。结果共纳入13项研究,涉及13011名研究对象。MRI辅助钼靶筛查致密型乳腺女性乳腺癌的灵敏度为0.94(95%CI为0.87~0.97),特异度为0.87(95%CI为0.82~0.91),阳性预测值中位数及四分位数间距为0.10(0.07~0.18)。亚组分析显示,MRI快速检查法的灵敏度(0.97 vs 0.92,P=0.42)和特异度(0.90 vs 0.86,P=0.03)不劣于MRI常规检查法。结论MRI辅助钼靶筛查致密型乳腺女性乳腺癌灵敏度较高,特异度略低,用于人群筛查时阳性预测值较低,宜谨慎解读筛查结果。MRI快速检查法省时、高效且准确性不劣于常规检查法,或可优先选用。展开更多
文摘To evaluate the value of 16-slice spiral CT in the demonstration of coronary artery and in the diagnose of coronary artery stenosis. Methods Plain and enhanced CT scans were performed with a 16-slice CT scanner (Sensation 16, Siemens, Germany) in 230 patients with suspected coronary heart disease (CHD). Parameters of the plain scan were: 120 kV, 133 mA, slice col-limation 16 mm×1.5 mm, rotation time 0.42 seconds, increment 1.5 mm, and slice width 3 mm. Parameters of the enhanced scan were: 120 kV, 500 mA, slice collimation 16 mm×0.75 mm, rotation time 0.42 seconds, increment 0.5 mm, and slice width 1 mm. Enhanced CT scan was performed with a rapid intravenous injection of 100 mL iothalamate meglumine (Ultravist) (370 mgI/mL) or Omnipaque (350 mgI/mL) and 30 mL 0.9% NaCl chaser bolus at a flow rate of 3.5 mL/s. Calcium scoring with plain scan images and two and three dimensional reconstruction with enhanced scan images were made in all cases, among which 30 cases underwent conventional coronary angiography. Demonstration of coronary arteries and their stenosis were evaluated and the factors that might influence the image quality were analyzed. Results Coronary calcium scores were calculated and coronary artery was demonstrated in our study. In the evaluationof image quality with volume rendering technique (VRT) images, 78.3% of the images were of the first class, 12.2% the sec-ond class, and 9.6% the third class. Multi-planar reconstruction (MPR) and maximal intensity projection (MIP) were better than VRT in the demonstration of small branches. The image quality was related to the heart rate, with or without arrhythmia, and breath-hold ability of patients. Comparative study of the stenosis of coronary arteries in 30 cases showed that the sensi-tivity and specificity of 16-slice coronary CT angiography (CTA) to diagnose significant stenosis were 95.8% and 94.8% resp-ectively. Conclusion As a non-invasive and quick method, 16-slice coronary CTA is sensitive and specific to diagnose the stenosis of coronary arterie
文摘目的汇总磁共振成像(MRI)辅助钼靶对致密型乳腺女性进行乳腺癌筛查的灵敏度、特异度及阳性预测值。方法检索PubMed、Web of Science、Embase、中国知网和万方数据库获取2021-09-30之前发表的相关文献。文献入选标准:(1)研究对象为致密型乳腺女性;(2)研究类型为观察性研究或干预性研究;(3)研究报告了钼靶联合MRI或钼靶阴性之后再行MRI筛查乳腺癌的灵敏度、特异度或阳性预测值。排除标准:(1)文献类型为综述、会议摘要、评论或社论等;(2)不能获取原文;(3)未报告准确性相关指标或阳性预测值且未提供基础数据。采用诊断试验质量评价工具诊断准确性研究质量评价标准-2(quality assessment of diagnostic accuracy studies-2,QUADAS-2)围绕病例选择、待评价的诊断试验、金标准等领域从研究偏倚与临床适用性2个维度评价文献质量,评价结果分为高风险、低风险和风险不详。结果共纳入13项研究,涉及13011名研究对象。MRI辅助钼靶筛查致密型乳腺女性乳腺癌的灵敏度为0.94(95%CI为0.87~0.97),特异度为0.87(95%CI为0.82~0.91),阳性预测值中位数及四分位数间距为0.10(0.07~0.18)。亚组分析显示,MRI快速检查法的灵敏度(0.97 vs 0.92,P=0.42)和特异度(0.90 vs 0.86,P=0.03)不劣于MRI常规检查法。结论MRI辅助钼靶筛查致密型乳腺女性乳腺癌灵敏度较高,特异度略低,用于人群筛查时阳性预测值较低,宜谨慎解读筛查结果。MRI快速检查法省时、高效且准确性不劣于常规检查法,或可优先选用。
