OBJECTIVE： To investigate the factors associated with sensory and motor recovery after the repair of upper limb peripheral nerve injuries. DATA SOURCES： The online PubMed database was searched for English articles d...OBJECTIVE： To investigate the factors associated with sensory and motor recovery after the repair of upper limb peripheral nerve injuries. DATA SOURCES： The online PubMed database was searched for English articles describing outcomes after the repair of median, ulnar, radial, and digital nerve injuries in humans with a publication date between 1 January 1990 and 16 February 2011. STUDY SELECTION： The following types of article were selected： （1） clinical trials describ- ing the repair of median, ulnar, radial, and digital nerve injuries published in English; and （2） studies that reported sufficient patient information, including age, mechanism of injury, nerve injured, injury location, defect length, repair time, repair method, and repair materials. SPSS 13.0 software was used to perform univariate and multivariate logistic regression analyses and to in- vestigate the patient and intervention factors associated with outcomes. MAIN OUTCOME MEASURES： Sensory function was assessed using the Mackinnon-Dellon scale and motor function was assessed using the manual muscle test. Satisfactory motor recovery was defined as grade M4 or M5, and satisfactory sensory recovery was defined as grade S3＋ or S4. RESULTS： Seventy-one articles were included in this study. Univariate and multivariate logistic regression analyses showed that repair time, repair materials, and nerve injured were inde- pendent predictors of outcome after the repair of nerve injuries （P 〈 0.05）, and that the nerve injured was the main factor affecting the rate of good to excellent recovery. CONCLUSION： Predictors of outcome after the repair of peripheral nerve injuries include age, gender, repair time, repair materials, nerve injured, defect length, and duration of follow-up.展开更多
目的:探讨口腔颌面部间隙感染患者不良结局的发生情况及相关影响因素,为其治疗和预防提供参考。方法:选择长沙市第四医院2011年1月-2020年6月收治的口腔颌面部间隙感染的患者为研究对象。通过医院信息管理系统(hospital information sys...目的:探讨口腔颌面部间隙感染患者不良结局的发生情况及相关影响因素,为其治疗和预防提供参考。方法:选择长沙市第四医院2011年1月-2020年6月收治的口腔颌面部间隙感染的患者为研究对象。通过医院信息管理系统(hospital information system,HIS)收集患者的临床资料,采用描述流行病学分析方法进行分析,采用单因素分析和多因素Logistic线性回归方法对口腔颌面部间隙感染患者不良结局的相关影响因素进行分析。结果:共收集到249例口腔颌面部间隙感染患者的临床资料,其中32例出现不良结局,发生率为12.85%,其中发生相关严重并发症27例、放弃治疗3例、死亡2例。多因素Logistic回归分析结果显示,年龄越大(OR=0.563)、感染至就诊时间越长(OR=1.324)、累及间隙越多(OR=0.441)、呼吸困难(OR=1.715)、合并糖尿病(OR=2.261)、中性粒细胞计数>0.9×10^(9)/L(OR=1.505)、C-反应蛋白≥10 mg/mL(OR=2.231)是口腔颌面部间隙感染患者发生不良结局的危险因素。结论:口腔颌面部间隙感染患者不良结局的发生率较高,与年龄、感染至就诊时间、累及间隙情况、呼吸困难、合并糖尿病、中性粒细胞计数和C-反应蛋白水平等因素有高相关性,临床应针对存在这些危险因素的患者加强干预和监护。展开更多
基金supported by the National High-Technology Research and Development Program of China(863 Program),No.2012A A020507985 Program of Sun Yat-sen University,No.90035-3283312+1 种基金Specialized Research Fund for the Doctoral Program of Higher Education,No.20120171120075Doctoral Start-up Project of the Natural Science Foundation of Guangdong Province,No.S201204006336
文摘OBJECTIVE： To investigate the factors associated with sensory and motor recovery after the repair of upper limb peripheral nerve injuries. DATA SOURCES： The online PubMed database was searched for English articles describing outcomes after the repair of median, ulnar, radial, and digital nerve injuries in humans with a publication date between 1 January 1990 and 16 February 2011. STUDY SELECTION： The following types of article were selected： （1） clinical trials describ- ing the repair of median, ulnar, radial, and digital nerve injuries published in English; and （2） studies that reported sufficient patient information, including age, mechanism of injury, nerve injured, injury location, defect length, repair time, repair method, and repair materials. SPSS 13.0 software was used to perform univariate and multivariate logistic regression analyses and to in- vestigate the patient and intervention factors associated with outcomes. MAIN OUTCOME MEASURES： Sensory function was assessed using the Mackinnon-Dellon scale and motor function was assessed using the manual muscle test. Satisfactory motor recovery was defined as grade M4 or M5, and satisfactory sensory recovery was defined as grade S3＋ or S4. RESULTS： Seventy-one articles were included in this study. Univariate and multivariate logistic regression analyses showed that repair time, repair materials, and nerve injured were inde- pendent predictors of outcome after the repair of nerve injuries （P 〈 0.05）, and that the nerve injured was the main factor affecting the rate of good to excellent recovery. CONCLUSION： Predictors of outcome after the repair of peripheral nerve injuries include age, gender, repair time, repair materials, nerve injured, defect length, and duration of follow-up.
文摘目的:探讨口腔颌面部间隙感染患者不良结局的发生情况及相关影响因素,为其治疗和预防提供参考。方法:选择长沙市第四医院2011年1月-2020年6月收治的口腔颌面部间隙感染的患者为研究对象。通过医院信息管理系统(hospital information system,HIS)收集患者的临床资料,采用描述流行病学分析方法进行分析,采用单因素分析和多因素Logistic线性回归方法对口腔颌面部间隙感染患者不良结局的相关影响因素进行分析。结果:共收集到249例口腔颌面部间隙感染患者的临床资料,其中32例出现不良结局,发生率为12.85%,其中发生相关严重并发症27例、放弃治疗3例、死亡2例。多因素Logistic回归分析结果显示,年龄越大(OR=0.563)、感染至就诊时间越长(OR=1.324)、累及间隙越多(OR=0.441)、呼吸困难(OR=1.715)、合并糖尿病(OR=2.261)、中性粒细胞计数>0.9×10^(9)/L(OR=1.505)、C-反应蛋白≥10 mg/mL(OR=2.231)是口腔颌面部间隙感染患者发生不良结局的危险因素。结论:口腔颌面部间隙感染患者不良结局的发生率较高,与年龄、感染至就诊时间、累及间隙情况、呼吸困难、合并糖尿病、中性粒细胞计数和C-反应蛋白水平等因素有高相关性,临床应针对存在这些危险因素的患者加强干预和监护。
