A system for in vitro investigation of ultrasound contrast agent＇s enhancement effect is presented and evaluated. It includes the digital B-mode ultrasound scanner Belson3000A, the tissue-mimicking ultrasound phantom...A system for in vitro investigation of ultrasound contrast agent＇s enhancement effect is presented and evaluated. It includes the digital B-mode ultrasound scanner Belson3000A, the tissue-mimicking ultrasound phantoms and the software which is used for image quantitative analysis. The linear range, optimal settings and repeatability of the system are assessed and explored by scanning the ultrasound phantoms with different reflective intensities. The measurements are performed under an acoustic power from 4.8 to 12.3 mW, the scanner centre frequency is 3.5 MH and the gain setting is 50 dB. Both a self-made surfactant encapsulated microbubble and a commercial ultrasound contrast agent are scanned. The results show that the pixel intensity of ultrasonic images increases with the increase in the sound power, and for the stronger reflective phantoms of more particles, the increasing trend is much more evident. The system is optimal for evaluating the microbubble contrast agents＇ enhancement effects. It presents a simple, effective and real-time means for characterizing the enhancement ability of microbubbles.展开更多
Ultrasound guided breast biopsy navigation system with a graphical user interface and a passive robotic needle holder is developed to increase the performance and reliability of the radiologist.Ultrasound calibration ...Ultrasound guided breast biopsy navigation system with a graphical user interface and a passive robotic needle holder is developed to increase the performance and reliability of the radiologist.Ultrasound calibration and tool tip calibration are required before using the system.A ladder phantom is developed to be used for ultrasound calibration in real time system with only one ultrasound image required.The passive robotic needle holder structure results in an identity matrix for the makes the rotation matrix;therefore,only translation and scaling are required in the system.This method can be applied to multiple ultrasound depths,which has a relationship at each depth and a relationship to the ultrasound image on the display.The results show high accuracy(<1 mm.)and rapid calibration(5–10 minutes)which is suitable for a real time system like a breast biopsy navigation system based on tests with a breast phantom.展开更多
基金The National Basic Research Program of China (973Program) (No.2006CB933206)the National Natural Science Foundation of China(No.50872021,60725101)
文摘A system for in vitro investigation of ultrasound contrast agent＇s enhancement effect is presented and evaluated. It includes the digital B-mode ultrasound scanner Belson3000A, the tissue-mimicking ultrasound phantoms and the software which is used for image quantitative analysis. The linear range, optimal settings and repeatability of the system are assessed and explored by scanning the ultrasound phantoms with different reflective intensities. The measurements are performed under an acoustic power from 4.8 to 12.3 mW, the scanner centre frequency is 3.5 MH and the gain setting is 50 dB. Both a self-made surfactant encapsulated microbubble and a commercial ultrasound contrast agent are scanned. The results show that the pixel intensity of ultrasonic images increases with the increase in the sound power, and for the stronger reflective phantoms of more particles, the increasing trend is much more evident. The system is optimal for evaluating the microbubble contrast agents＇ enhancement effects. It presents a simple, effective and real-time means for characterizing the enhancement ability of microbubbles.
基金the Computer-Integrated Intelligent Medical System Project under the National Research University Grant through Mahidol Universitythe Integration of Surgical Navigation and Surgical Robotics for Breast Biopsy in Breast Cancer using Mammogram and ultrasound Images on Breast Mathematical Model Project under the Government Research Budget through Mahidol University(Grant 111-2558)。
文摘Ultrasound guided breast biopsy navigation system with a graphical user interface and a passive robotic needle holder is developed to increase the performance and reliability of the radiologist.Ultrasound calibration and tool tip calibration are required before using the system.A ladder phantom is developed to be used for ultrasound calibration in real time system with only one ultrasound image required.The passive robotic needle holder structure results in an identity matrix for the makes the rotation matrix;therefore,only translation and scaling are required in the system.This method can be applied to multiple ultrasound depths,which has a relationship at each depth and a relationship to the ultrasound image on the display.The results show high accuracy(<1 mm.)and rapid calibration(5–10 minutes)which is suitable for a real time system like a breast biopsy navigation system based on tests with a breast phantom.
