Electrochemical micromachining （EMM） technology for fabricating micro structures is presented in this article. By applying ultra short pulses, dissolution of a workpiece can be restricted to the region very close to...Electrochemical micromachining （EMM） technology for fabricating micro structures is presented in this article. By applying ultra short pulses, dissolution of a workpiece can be restricted to the region very close to the electrode. First, an EMM system for meeting the requirements of the EMM process is established. Second, sets of experiments is carried out to investigate the influence of some of the predominant electrochemical process parameters such as electrical parameters, feed rate, electrode geometry features and electrolyte composition on machining quality, especially the influences of pulse on time on shape precision and working end shape of electrode on machined surface quality. Finally, after the preliminary experiments, a complex microstructure with good shape precision and surface quality is successfully obtained.展开更多
目的:探究痤疮清热合剂加减联合超脉冲点阵CO_(2)激光在寻常痤疮治疗中的应用效果。方法:选取2017年1月-2019年12月在笔者医院就诊的100例寻常痤疮患者为研究对象,随机分为观察组和对照组,每组50例。两组患者均给予超脉冲点阵CO_(2)激...目的:探究痤疮清热合剂加减联合超脉冲点阵CO_(2)激光在寻常痤疮治疗中的应用效果。方法:选取2017年1月-2019年12月在笔者医院就诊的100例寻常痤疮患者为研究对象,随机分为观察组和对照组,每组50例。两组患者均给予超脉冲点阵CO_(2)激光治疗,观察组在此基础上联合痤疮清热合剂加减治疗,持续治疗3个月后比较两组患者的炎症指标、血清睾酮水平、皮肤生理指标、中医皮损积分、痤疮瘢痕严重程度、生活质量及复发率。结果:治疗后,观察组的皮损程度、皮损数量、皮损肿痛、皮损颜色积分均低于对照组(P<0.05);观察组痤疮瘢痕权重评分(échelle d’évaluation chiniquc dcs cicatrices d’acné,ECCA)均低于对照组(P<0.05);观察组的角质层含水量高于对照组,油脂含量及酸碱度(pH)低于对照组(P<0.05);观察组的白介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)、白介素-8(IL-8)、血清睾酮(T)水平低于对照组(P<0.05);观察组的痤疮患者特异性生活质量量表(Acne-specific quality of life scale,Acne-QOL)评分高于对照组,1年内复发率低于对照组(P<0.05),差异均有统计学意义。结论:痤疮清热合剂加减联合超脉冲点阵CO_(2)激光治疗寻常痤疮,可有效缓解临床症状,改善皮肤生理状态及痤疮瘢痕,提高患者生活质量,抑制复发。展开更多
基金National Natural Science Foundation of China (50635040)National High-tech Research and Development Program (2009AA04Z302)Jiangsu Provincial Natural Science Foundation (BK2008043)
文摘Electrochemical micromachining （EMM） technology for fabricating micro structures is presented in this article. By applying ultra short pulses, dissolution of a workpiece can be restricted to the region very close to the electrode. First, an EMM system for meeting the requirements of the EMM process is established. Second, sets of experiments is carried out to investigate the influence of some of the predominant electrochemical process parameters such as electrical parameters, feed rate, electrode geometry features and electrolyte composition on machining quality, especially the influences of pulse on time on shape precision and working end shape of electrode on machined surface quality. Finally, after the preliminary experiments, a complex microstructure with good shape precision and surface quality is successfully obtained.
文摘目的:探究痤疮清热合剂加减联合超脉冲点阵CO_(2)激光在寻常痤疮治疗中的应用效果。方法:选取2017年1月-2019年12月在笔者医院就诊的100例寻常痤疮患者为研究对象,随机分为观察组和对照组,每组50例。两组患者均给予超脉冲点阵CO_(2)激光治疗,观察组在此基础上联合痤疮清热合剂加减治疗,持续治疗3个月后比较两组患者的炎症指标、血清睾酮水平、皮肤生理指标、中医皮损积分、痤疮瘢痕严重程度、生活质量及复发率。结果:治疗后,观察组的皮损程度、皮损数量、皮损肿痛、皮损颜色积分均低于对照组(P<0.05);观察组痤疮瘢痕权重评分(échelle d’évaluation chiniquc dcs cicatrices d’acné,ECCA)均低于对照组(P<0.05);观察组的角质层含水量高于对照组,油脂含量及酸碱度(pH)低于对照组(P<0.05);观察组的白介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)、白介素-8(IL-8)、血清睾酮(T)水平低于对照组(P<0.05);观察组的痤疮患者特异性生活质量量表(Acne-specific quality of life scale,Acne-QOL)评分高于对照组,1年内复发率低于对照组(P<0.05),差异均有统计学意义。结论:痤疮清热合剂加减联合超脉冲点阵CO_(2)激光治疗寻常痤疮,可有效缓解临床症状,改善皮肤生理状态及痤疮瘢痕,提高患者生活质量,抑制复发。
