通过1-烯丙基咪唑与1,4-丁基磺酸内酯反应制备的两性离子分别与硫酸、三氟甲基磺酸、磷钨酸、磷钼酸和硅钨酸直接反应制备了5种磺酸功能化离子液体。采用1 H NMR、FTIR、TG/DTA等技术手段对其结构及热稳定性进行了表征。最后通过催化油...通过1-烯丙基咪唑与1,4-丁基磺酸内酯反应制备的两性离子分别与硫酸、三氟甲基磺酸、磷钨酸、磷钼酸和硅钨酸直接反应制备了5种磺酸功能化离子液体。采用1 H NMR、FTIR、TG/DTA等技术手段对其结构及热稳定性进行了表征。最后通过催化油酸与甲醇酯化反应制生物柴油过程对催化剂的催化活性和重复使用性进行了评价。结果表明,5种离子液体均具有高催化活性(高于浓硫酸),并且重复使用4次后,催化活性基本保持不变。3种杂多酸离子液体不溶于产物,以固态形式与产物混合,为其回收和重复利用提供了有利条件。展开更多
Sulfonic acid functionalized pyridinium chloride [pyridine-SO3 H]Cl has been synthesized as a novel Brnsted acidic ionic liquid and characterized on the basis of its FT-IR,1H and 13C NMR,MS,ther-mogravimetry,and deriv...Sulfonic acid functionalized pyridinium chloride [pyridine-SO3 H]Cl has been synthesized as a novel Brnsted acidic ionic liquid and characterized on the basis of its FT-IR,1H and 13C NMR,MS,ther-mogravimetry,and derivative thermogravimetry data.The material has also been used as a highly efficient,homogeneous,and reusable catalyst for the preparation of hexahydroquinolines according to the one-pot multi-component condensation of arylaldehydes,dimedone(5,5-dimethylcyclohexane-1,3-dione),β-ketoesters,and ammonium acetate under solvent-free conditions.展开更多
An efficient synthesis of novel coumarin derivatives via a three-component condensation of 4-hydroxycoumarin, aldehydes and aromatic amines catalyzed by sulfonic acid functionalized ionic liquid L-2-（hydroxymethyl）-...An efficient synthesis of novel coumarin derivatives via a three-component condensation of 4-hydroxycoumarin, aldehydes and aromatic amines catalyzed by sulfonic acid functionalized ionic liquid L-2-（hydroxymethyl）- 1-（4-sulfobutyl）pyrrolidinium hydrogen sulfate （[HYSBPI]·HSO4） is reported. The condensed product was obtained with excellent yields in water under microwave irradiation condition. The antitumor activities of all the synthesized compounds were assessed on two different human cancer cell lines （A-549 and MCF-7）, and the results showed that these compounds had weak-to-good antitumor activities and their IC50 ranged from 0.05 to more than 100 μmol.L-1.展开更多
文摘通过1-烯丙基咪唑与1,4-丁基磺酸内酯反应制备的两性离子分别与硫酸、三氟甲基磺酸、磷钨酸、磷钼酸和硅钨酸直接反应制备了5种磺酸功能化离子液体。采用1 H NMR、FTIR、TG/DTA等技术手段对其结构及热稳定性进行了表征。最后通过催化油酸与甲醇酯化反应制生物柴油过程对催化剂的催化活性和重复使用性进行了评价。结果表明,5种离子液体均具有高催化活性(高于浓硫酸),并且重复使用4次后,催化活性基本保持不变。3种杂多酸离子液体不溶于产物,以固态形式与产物混合,为其回收和重复利用提供了有利条件。
基金partial support for this work from the Research Affairs Office of Sayyed Jamaleddin Asadabadi University,Bu-Ali Sina University(Grant no. 32-1716 entitled development of chemical methods,reagents and molecules)the Center of Excellence in Development of Chemical Method(CEDCM),Hamedan,I.R. Iran
文摘Sulfonic acid functionalized pyridinium chloride [pyridine-SO3 H]Cl has been synthesized as a novel Brnsted acidic ionic liquid and characterized on the basis of its FT-IR,1H and 13C NMR,MS,ther-mogravimetry,and derivative thermogravimetry data.The material has also been used as a highly efficient,homogeneous,and reusable catalyst for the preparation of hexahydroquinolines according to the one-pot multi-component condensation of arylaldehydes,dimedone(5,5-dimethylcyclohexane-1,3-dione),β-ketoesters,and ammonium acetate under solvent-free conditions.
基金We thank the National Basic Research Program of China （973 Program） （No. 2003CB 114400） and the Na- tional Natural Science Foundation of China （Nos. 20476098 and 20676123） for financial support.
文摘An efficient synthesis of novel coumarin derivatives via a three-component condensation of 4-hydroxycoumarin, aldehydes and aromatic amines catalyzed by sulfonic acid functionalized ionic liquid L-2-（hydroxymethyl）- 1-（4-sulfobutyl）pyrrolidinium hydrogen sulfate （[HYSBPI]·HSO4） is reported. The condensed product was obtained with excellent yields in water under microwave irradiation condition. The antitumor activities of all the synthesized compounds were assessed on two different human cancer cell lines （A-549 and MCF-7）, and the results showed that these compounds had weak-to-good antitumor activities and their IC50 ranged from 0.05 to more than 100 μmol.L-1.
