贵州丹寨南皋在寒武纪属于扬子板块深水相区,最近在该区寒武系下部牛蹄塘组中上部黑色泥页岩中发现了大量保存完好的海绵动物化石,共9属10种。文中描述其中比较典型的海绵动物化石5属5种:赫兹海绵未定种Hintzespongia sp.,杯形对角海绵D...贵州丹寨南皋在寒武纪属于扬子板块深水相区,最近在该区寒武系下部牛蹄塘组中上部黑色泥页岩中发现了大量保存完好的海绵动物化石,共9属10种。文中描述其中比较典型的海绵动物化石5属5种:赫兹海绵未定种Hintzespongia sp.,杯形对角海绵Diagoniella cyathiformis(Dawson,1889),密集鬃毛状海绵Saeta-spongia densa Mehl and Reitner in Steineret al.,1993,大坪三岔五射海绵Sanshapentella dapingi Mehl and Erdt-mann,1994和羽状光芒海绵Solactiniella plumata Mehl and Reitner in Steineret al.,1993。在这套整体缺氧的黑色泥页岩中有如此多而完整的海绵动物化石的保存,可能是由于上涌洋流、水流或海平面的变化等导致短暂的充氧事件,加上多幕次的热水沉积,提供大量食料,从而利于需氧量相对较低的原始后生动物--海绵动物的大量繁盛。展开更多
Loofa sponge （LS） immobilized biomass of Chlorella sorokiniana （LSIBCS）, isolated from industrial wastewater, was investigated as a new biosorbent for the removal of Cr（Ⅲ） from aqueous solution. A comparison of...Loofa sponge （LS） immobilized biomass of Chlorella sorokiniana （LSIBCS）, isolated from industrial wastewater, was investigated as a new biosorbent for the removal of Cr（Ⅲ） from aqueous solution. A comparison of the biosorption of Cr（Ⅲ） by LSIBCS and free biomass of C. sorokiniana （FBCS） from 10-300 mg Cr（Ⅲ）/L aqueous solutions showed an increase in uptake of 17.79% when the microalgal biomass was immobilized onto loofa sponge. Maximum biosorption capacity for LSIBCS and FBCS was found to be 69.26 and 58.80 mg Cr（Ⅲ）/g biosorbent, respectively, whereas the amount of Cr（Ⅲ） ions adsorbed onto naked LS was 4.97 mg/g. The kinetics of Cr（Ⅲ） biosorption was extremely rapid and equilibrium was established in about 15 and 20 min by LSIBCS and FBCS, respectively. The biosorption equilibrium was well defined by Langmuir adsorption isotherm model. The biosorption kinetics followed the pseudo-second order kinetic model. The biosorption was found to be pH dependent and the maximum sorption occurred at the solution pH 4.0. Desorption studies showed that 98% of the adsorbed Cr（Ⅲ） could be desorbed with 0.1 mol/L HNO3, while other desorbing agents were less effective in the order： EDTA 〉 H2SO4 〉 CH3COOH 〉 HCl. The regenerated LSIBCS retained 92.68% of the initial Cr（Ⅲ） binding capacity up to five cycles of reuse in continuous flow-fixed bed columns. The study revealed that LSIBCS could be used as an effective biosorbent for the removal of Cr（Ⅲ） from wastewater.展开更多
As a newly discovered type of RNA, circular RNAs(circRNAs) are widespread throughout the eukaryotic genome. The expression of circRNAs is regulated by both cis-elements and trans-factors, and the expression pattern of...As a newly discovered type of RNA, circular RNAs(circRNAs) are widespread throughout the eukaryotic genome. The expression of circRNAs is regulated by both cis-elements and trans-factors, and the expression pattern of circRNAs is cell type-and diseasespecific. Similar to other types of non-coding RNAs, functions of circRNAs are also versatile. CircRNAs have been reported previously to function as microRNA(miRNA) sponges, protein sponges, coding RNAs or scaffolds for protein complexes.Recently, several circRNAs have been reported to play important roles in human malignancies, including glioma. Here, we reviewed several reports related to circRNAs and glioma, as well as the potential diagnostic and therapeutic applications of circRNAs in brain cancer. In general, some circRNAs, such as circSMARCA5 and circCFH, are found to be expressed in a gliomaspecific pattern, these circRNAs may be used as tumor biomarkers. In addition, some circRNAs have been found to play oncogenic roles in glioma(e.g., circNFIX and circNT5E), whereas others have been reported to function as tumor suppressors(e.g.,circFBXW7 and circSHPRH). Furthermore, circRNA is a good tool for protein expression because of its higher stability compared to linear RNAs. Thus, circRNAs may also be an ideal choice for gene/protein delivery in future brain cancer therapies. There are some challenges in circRNA research in glioma and other diseases. Research related to circRNAs in glioma is comparatively new and many mysteries remain to be solved.展开更多
Since 2014, China has been implementing the Sponge City Construction initiative, which represents an enormous and unprecedented effort by any government in the world for achieving urban sustainability. According to pr...Since 2014, China has been implementing the Sponge City Construction initiative, which represents an enormous and unprecedented effort by any government in the world for achieving urban sustainability. According to preliminary estimates, the total investment on the Sponge City Plan is roughly 100 to 150 million Yuan （RMB） （$15 to $22.5 million） average per square kilometer or 10 Trillion Yuan （RMB） （$1.5 Trillion） for the 657 cities nationwide. The Sponge City Plan （SCP） calls for the use of natural processes such as soil and vegetation as part of the urban runoff control strategy, which is similar to that of low impact development （LID） and green infrastructure （G1） practices being promoted in many parts of the world. The SCP includes as its goals not only effective urban flood control, but also rainwater harvest, water quality improvement and ecological restoration. So far, the SCP implementation has encountered-some barriers and challenges due to many factors. The present paper presents a review of those barriers and challenges, oftizrs discussions and recommendations on several technical aspects such as control goals and objectives; planning/design and construction of LID/GI practices; performance evaluation. Several key recommendations are proposed on Sponge City implementation strategy, Site-specific regulatory fi＇amework and technical gmdance, Product innovation and certification, LID/GI Project financing, LID/G1 profcssional training and certification, public outreach and education. It is expected that the successful implemen!atiun of the. SCP not only will bring about a sustainable, eco-friendly urbanization process in China, but also contribute enormously to the LID/Gl research and development with the vast amount of relevant data and experiences generated from the Sponge City construction projects.展开更多
BACKGROUND Compared with traditional open surgery,laparoscopic surgery is preferred due to the advantages of less trauma,less pain,and faster recovery.Nevertheless,many patients still suffer from postoperative pain re...BACKGROUND Compared with traditional open surgery,laparoscopic surgery is preferred due to the advantages of less trauma,less pain,and faster recovery.Nevertheless,many patients still suffer from postoperative pain resulting from the surgical incision and associated tissue injury.Many researchers have reported methods to improve postoperative pain control,but there is not a simple and effective method that can be clinically adopted in a widespread manner.We designed this study to prove the hypothesis that application of ropivacaine in the port site and operative site in patients is an effective and convenient method which can decrease postoperative pain and accelerate recovery.AIM To evaluate the effects of ropivacaine on pain control after laparoscopic hepatectomy and its contribution to patient recovery.METHODS From May 2017 to November 2018,146 patients undergoing laparoscopic hepatectomy were randomized to receive infiltration of either 7.5 mg/mL ropivacaine around the trocar insertions,incision,and cutting surface of the liver(with a gelatin sponge soaked with ropivacaine)at the end of surgery(ropivacaine group),or normal saline(5 mL)at the same sites at the end of surgery(control group).The degree of pain,nausea,vomiting,heart rate(HR),and blood pressure were collected.The length of postoperative hospitalization,complications,and the levels of stress hormones were also compared between the two groups.RESULTS Compared with the control group,the ropivacaine group showed reduced postoperative pain at rest within 12 h(P<0.05),and pain on movement was reduced within 48 h.The levels of epinephrine,norepinephrine,and cortisol at 24 and 48 h,HR,blood pressure,and cumulative sufentanil consumption in the ropivacaine group were significantly lower than those in the control group(P<0.05).In the ropivacaine group,hospitalization after operation was shorter,but the difference was not statistically significant.There were no significant differences in postoperative nausea,vomiting,or other complications,including hydrotho展开更多
文摘贵州丹寨南皋在寒武纪属于扬子板块深水相区,最近在该区寒武系下部牛蹄塘组中上部黑色泥页岩中发现了大量保存完好的海绵动物化石,共9属10种。文中描述其中比较典型的海绵动物化石5属5种:赫兹海绵未定种Hintzespongia sp.,杯形对角海绵Diagoniella cyathiformis(Dawson,1889),密集鬃毛状海绵Saeta-spongia densa Mehl and Reitner in Steineret al.,1993,大坪三岔五射海绵Sanshapentella dapingi Mehl and Erdt-mann,1994和羽状光芒海绵Solactiniella plumata Mehl and Reitner in Steineret al.,1993。在这套整体缺氧的黑色泥页岩中有如此多而完整的海绵动物化石的保存,可能是由于上涌洋流、水流或海平面的变化等导致短暂的充氧事件,加上多幕次的热水沉积,提供大量食料,从而利于需氧量相对较低的原始后生动物--海绵动物的大量繁盛。
文摘Loofa sponge （LS） immobilized biomass of Chlorella sorokiniana （LSIBCS）, isolated from industrial wastewater, was investigated as a new biosorbent for the removal of Cr（Ⅲ） from aqueous solution. A comparison of the biosorption of Cr（Ⅲ） by LSIBCS and free biomass of C. sorokiniana （FBCS） from 10-300 mg Cr（Ⅲ）/L aqueous solutions showed an increase in uptake of 17.79% when the microalgal biomass was immobilized onto loofa sponge. Maximum biosorption capacity for LSIBCS and FBCS was found to be 69.26 and 58.80 mg Cr（Ⅲ）/g biosorbent, respectively, whereas the amount of Cr（Ⅲ） ions adsorbed onto naked LS was 4.97 mg/g. The kinetics of Cr（Ⅲ） biosorption was extremely rapid and equilibrium was established in about 15 and 20 min by LSIBCS and FBCS, respectively. The biosorption equilibrium was well defined by Langmuir adsorption isotherm model. The biosorption kinetics followed the pseudo-second order kinetic model. The biosorption was found to be pH dependent and the maximum sorption occurred at the solution pH 4.0. Desorption studies showed that 98% of the adsorbed Cr（Ⅲ） could be desorbed with 0.1 mol/L HNO3, while other desorbing agents were less effective in the order： EDTA 〉 H2SO4 〉 CH3COOH 〉 HCl. The regenerated LSIBCS retained 92.68% of the initial Cr（Ⅲ） binding capacity up to five cycles of reuse in continuous flow-fixed bed columns. The study revealed that LSIBCS could be used as an effective biosorbent for the removal of Cr（Ⅲ） from wastewater.
文摘As a newly discovered type of RNA, circular RNAs(circRNAs) are widespread throughout the eukaryotic genome. The expression of circRNAs is regulated by both cis-elements and trans-factors, and the expression pattern of circRNAs is cell type-and diseasespecific. Similar to other types of non-coding RNAs, functions of circRNAs are also versatile. CircRNAs have been reported previously to function as microRNA(miRNA) sponges, protein sponges, coding RNAs or scaffolds for protein complexes.Recently, several circRNAs have been reported to play important roles in human malignancies, including glioma. Here, we reviewed several reports related to circRNAs and glioma, as well as the potential diagnostic and therapeutic applications of circRNAs in brain cancer. In general, some circRNAs, such as circSMARCA5 and circCFH, are found to be expressed in a gliomaspecific pattern, these circRNAs may be used as tumor biomarkers. In addition, some circRNAs have been found to play oncogenic roles in glioma(e.g., circNFIX and circNT5E), whereas others have been reported to function as tumor suppressors(e.g.,circFBXW7 and circSHPRH). Furthermore, circRNA is a good tool for protein expression because of its higher stability compared to linear RNAs. Thus, circRNAs may also be an ideal choice for gene/protein delivery in future brain cancer therapies. There are some challenges in circRNA research in glioma and other diseases. Research related to circRNAs in glioma is comparatively new and many mysteries remain to be solved.
基金We gratefully acknowledge financial support from the Beijing Natural Science Foundation Project （No. 8161003）, Natural Science Foundation Project （No. 51278267）, and the National Water Pollution Control Special Project （No. 2011ZX07301-003）. Several points and the contents in the manuscript are discussed with many experts during 2016 International Low Impact Conference in Beijing.
文摘Since 2014, China has been implementing the Sponge City Construction initiative, which represents an enormous and unprecedented effort by any government in the world for achieving urban sustainability. According to preliminary estimates, the total investment on the Sponge City Plan is roughly 100 to 150 million Yuan （RMB） （$15 to $22.5 million） average per square kilometer or 10 Trillion Yuan （RMB） （$1.5 Trillion） for the 657 cities nationwide. The Sponge City Plan （SCP） calls for the use of natural processes such as soil and vegetation as part of the urban runoff control strategy, which is similar to that of low impact development （LID） and green infrastructure （G1） practices being promoted in many parts of the world. The SCP includes as its goals not only effective urban flood control, but also rainwater harvest, water quality improvement and ecological restoration. So far, the SCP implementation has encountered-some barriers and challenges due to many factors. The present paper presents a review of those barriers and challenges, oftizrs discussions and recommendations on several technical aspects such as control goals and objectives; planning/design and construction of LID/GI practices; performance evaluation. Several key recommendations are proposed on Sponge City implementation strategy, Site-specific regulatory fi＇amework and technical gmdance, Product innovation and certification, LID/GI Project financing, LID/G1 profcssional training and certification, public outreach and education. It is expected that the successful implemen!atiun of the. SCP not only will bring about a sustainable, eco-friendly urbanization process in China, but also contribute enormously to the LID/Gl research and development with the vast amount of relevant data and experiences generated from the Sponge City construction projects.
基金Supported by the National Natural Science Foundation of China,No.81571367Technological Project of Shandong Province,No.2017GSF218021
文摘BACKGROUND Compared with traditional open surgery,laparoscopic surgery is preferred due to the advantages of less trauma,less pain,and faster recovery.Nevertheless,many patients still suffer from postoperative pain resulting from the surgical incision and associated tissue injury.Many researchers have reported methods to improve postoperative pain control,but there is not a simple and effective method that can be clinically adopted in a widespread manner.We designed this study to prove the hypothesis that application of ropivacaine in the port site and operative site in patients is an effective and convenient method which can decrease postoperative pain and accelerate recovery.AIM To evaluate the effects of ropivacaine on pain control after laparoscopic hepatectomy and its contribution to patient recovery.METHODS From May 2017 to November 2018,146 patients undergoing laparoscopic hepatectomy were randomized to receive infiltration of either 7.5 mg/mL ropivacaine around the trocar insertions,incision,and cutting surface of the liver(with a gelatin sponge soaked with ropivacaine)at the end of surgery(ropivacaine group),or normal saline(5 mL)at the same sites at the end of surgery(control group).The degree of pain,nausea,vomiting,heart rate(HR),and blood pressure were collected.The length of postoperative hospitalization,complications,and the levels of stress hormones were also compared between the two groups.RESULTS Compared with the control group,the ropivacaine group showed reduced postoperative pain at rest within 12 h(P<0.05),and pain on movement was reduced within 48 h.The levels of epinephrine,norepinephrine,and cortisol at 24 and 48 h,HR,blood pressure,and cumulative sufentanil consumption in the ropivacaine group were significantly lower than those in the control group(P<0.05).In the ropivacaine group,hospitalization after operation was shorter,but the difference was not statistically significant.There were no significant differences in postoperative nausea,vomiting,or other complications,including hydrotho
