BACKGROUND: In the rehabilitation of stroke patients, clinicians usually concentrate on motor problems, such as spasm of limbs and restriction of joint motion, while sensory and perceptive problems are almost always ...BACKGROUND: In the rehabilitation of stroke patients, clinicians usually concentrate on motor problems, such as spasm of limbs and restriction of joint motion, while sensory and perceptive problems are almost always neglected, although they are just as important. One such area is the sensory disorder. OBJECTIVE: To evaluate the motor function and activities of daily living in stroke patients with and without sensory disorders after treatment of integrated western and Chinese medicine. DESIGN: A non-randomized synchronically controlled trial. SETTING: First Affiliated Hospital of Tianjin College of Traditional Chinese Medicine. PARTICIPANTS: Totally 500 stroke inpatients were selected from the Department of Acupuncture and Massage, the First Affiliated Hospital of Tianjin College of Traditional Chinese Medicine from January 2003 to December 2004. They all had suffered from stroke in the last 4 weeks and accompanied by sensory disorder of the ipsilateral limb to different severity. The patients were all accorded with the Diagnostic and Efficacy Evaluative Standards for Stroke (in trial) set by the Encephalopathy Emergency Assistant Group, the State Administration of Traditional Chinese Medicine in 1995, and they were diagnosed by imaging examination. The patients were stratified into sensory disorder group (n =220) and normal sense group (n =280). Informed consent for the detected items and therapeutic program was obtained from the relatives of all the participants. The study was approved by the hospital ethical committee. METHODS: All the patients were treated with acupuncture of Xing Nao Kai Qiao for restoring consciousness and inducing resuscitation, assisted by traditional Chinese medicine and western medicine specific to corresponding symptoms. The therapeutic principles were restoring consciousness and inducing resuscitation, nourishing liver and kidney, and dredging meridian. In addition, the patients were given western medical treatments for decreasing intracranial pressure, thrombol展开更多
目的:探讨益气通络方对丘脑型脑卒中感觉障碍患者血清炎症因子及血脂的影响。方法:将丘脑型脑卒中患者118例随机分两组各59例,对照组采用常规治疗,包括生活方式干预、药物治疗、物理疗法及其他对症治疗,观察组在此基础上加益气通络方,治...目的:探讨益气通络方对丘脑型脑卒中感觉障碍患者血清炎症因子及血脂的影响。方法:将丘脑型脑卒中患者118例随机分两组各59例,对照组采用常规治疗,包括生活方式干预、药物治疗、物理疗法及其他对症治疗,观察组在此基础上加益气通络方,治疗4周后比较两组患者临床疗效,治疗前后Fugl-meyer评分、Berg平衡量表(berg balance scale,BBS)评分、美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)评分及血清肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)、白细胞介素6(Interleukin-6,IL-6)、甘油三酯(triglyceride,TG)、总胆固醇(total cholesterol,TC)水平,并记录不良反应。结果:总有效率对照组为79.66%(47/59),观察组为93.22%(55/59),差异有统计学意义(P<0.05)。与治疗前相比,两组患者治疗后Fugl-meyer评分、BBS评分均升高,NIHSS评分及血清TNF-α、IL-6与TC、TG降低;与对照组比较,观察组患者治疗后Fugl-meyer评分、BBS评分升高,NIHSS评分及血清TNF-α、IL-6与TC、TG降低,差异有统计学意义(P<0.05)。治疗期间两组均无不良反应出现。结论:益气通络方治疗丘脑型脑卒中感觉障碍疗效确切,可改善患者感觉、平衡及神经功能,降低血脂和炎症因子水平。展开更多
基金the National Key Basic Study Development Planning of China (973 Program),No.2006CB504504
文摘BACKGROUND: In the rehabilitation of stroke patients, clinicians usually concentrate on motor problems, such as spasm of limbs and restriction of joint motion, while sensory and perceptive problems are almost always neglected, although they are just as important. One such area is the sensory disorder. OBJECTIVE: To evaluate the motor function and activities of daily living in stroke patients with and without sensory disorders after treatment of integrated western and Chinese medicine. DESIGN: A non-randomized synchronically controlled trial. SETTING: First Affiliated Hospital of Tianjin College of Traditional Chinese Medicine. PARTICIPANTS: Totally 500 stroke inpatients were selected from the Department of Acupuncture and Massage, the First Affiliated Hospital of Tianjin College of Traditional Chinese Medicine from January 2003 to December 2004. They all had suffered from stroke in the last 4 weeks and accompanied by sensory disorder of the ipsilateral limb to different severity. The patients were all accorded with the Diagnostic and Efficacy Evaluative Standards for Stroke (in trial) set by the Encephalopathy Emergency Assistant Group, the State Administration of Traditional Chinese Medicine in 1995, and they were diagnosed by imaging examination. The patients were stratified into sensory disorder group (n =220) and normal sense group (n =280). Informed consent for the detected items and therapeutic program was obtained from the relatives of all the participants. The study was approved by the hospital ethical committee. METHODS: All the patients were treated with acupuncture of Xing Nao Kai Qiao for restoring consciousness and inducing resuscitation, assisted by traditional Chinese medicine and western medicine specific to corresponding symptoms. The therapeutic principles were restoring consciousness and inducing resuscitation, nourishing liver and kidney, and dredging meridian. In addition, the patients were given western medical treatments for decreasing intracranial pressure, thrombol
文摘目的:探讨益气通络方对丘脑型脑卒中感觉障碍患者血清炎症因子及血脂的影响。方法:将丘脑型脑卒中患者118例随机分两组各59例,对照组采用常规治疗,包括生活方式干预、药物治疗、物理疗法及其他对症治疗,观察组在此基础上加益气通络方,治疗4周后比较两组患者临床疗效,治疗前后Fugl-meyer评分、Berg平衡量表(berg balance scale,BBS)评分、美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)评分及血清肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)、白细胞介素6(Interleukin-6,IL-6)、甘油三酯(triglyceride,TG)、总胆固醇(total cholesterol,TC)水平,并记录不良反应。结果:总有效率对照组为79.66%(47/59),观察组为93.22%(55/59),差异有统计学意义(P<0.05)。与治疗前相比,两组患者治疗后Fugl-meyer评分、BBS评分均升高,NIHSS评分及血清TNF-α、IL-6与TC、TG降低;与对照组比较,观察组患者治疗后Fugl-meyer评分、BBS评分升高,NIHSS评分及血清TNF-α、IL-6与TC、TG降低,差异有统计学意义(P<0.05)。治疗期间两组均无不良反应出现。结论:益气通络方治疗丘脑型脑卒中感觉障碍疗效确切,可改善患者感觉、平衡及神经功能,降低血脂和炎症因子水平。