Melatonin and gamma-aminobutyric acid（GABA） have been shown to regulate sleep. The nocturnal concentrations of melatonin, GABA and total antioxidants may relate to insomnia in stroke patients. In this prospective si...Melatonin and gamma-aminobutyric acid（GABA） have been shown to regulate sleep. The nocturnal concentrations of melatonin, GABA and total antioxidants may relate to insomnia in stroke patients. In this prospective single-center non-randomized controlled clinical trial performed in the China Rehabilitation Research Center, we analyzed the relationship of nocturnal concentrations of melatonin, GABA and total antioxidants with insomnia after stroke. Patients during rehabilitation of stroke were recruited and assigned to the insomnia group or non-insomnia group. Simultaneously, persons without stroke or insomnia served as normal controls. Each group contained 25 cases. The primary outcome was nocturnal concentrations of melatonin, GABA and total antioxidants in peripheral blood. The secondary outcomes were Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, Fatigue Severity Scale, Morningness-Eveningness Questionnaire（Chinese version）, and National Institute of Health Stroke Scale. The relationship of nocturnal concentrations of melatonin, GABA and total antioxidants with insomnia after stroke was analyzed and showed that they were lower in the insomnia group than in the non-insomnia group. The severity of stroke was higher in the insomnia group than in the non-insomnia group. Correlation analysis demonstrated that the nocturnal concentrations of melatonin and GABA were associated with insomnia after stroke. This trial was registered at Clinical Trials.gov, identifier： NCT03202121.展开更多
Fire numbers, burned areas and return intervals in each large scale forest type with average patch area of 500?km 2 in Heilongjiang Province during the period of 1980 to 1999 were obtained by overlapping the ignition ...Fire numbers, burned areas and return intervals in each large scale forest type with average patch area of 500?km 2 in Heilongjiang Province during the period of 1980 to 1999 were obtained by overlapping the ignition points and areas of 1482 forest fires with the Province’s forest type maps in the same period by means of GIS software ARC/INFO. Analysis on the data indicated that the effects of the forest types on fire occurrence and burned areas in the Province were not significant, thus it was not necessary to take forest types into consideration when forest fire hazard was rated on a large scale. Years long human fire suppression activities increased fire return intervals in the region. Comparison was also made on the effects of forest types on fires at various scales.展开更多
基金supported by the Optional Research Project of China Rehabilitation Research Center,No.2014-7the Sub-Project under National“Twelfth Five-Year”Plan for Science&Technology Support Project,No.2011BAI08B11
文摘Melatonin and gamma-aminobutyric acid（GABA） have been shown to regulate sleep. The nocturnal concentrations of melatonin, GABA and total antioxidants may relate to insomnia in stroke patients. In this prospective single-center non-randomized controlled clinical trial performed in the China Rehabilitation Research Center, we analyzed the relationship of nocturnal concentrations of melatonin, GABA and total antioxidants with insomnia after stroke. Patients during rehabilitation of stroke were recruited and assigned to the insomnia group or non-insomnia group. Simultaneously, persons without stroke or insomnia served as normal controls. Each group contained 25 cases. The primary outcome was nocturnal concentrations of melatonin, GABA and total antioxidants in peripheral blood. The secondary outcomes were Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, Fatigue Severity Scale, Morningness-Eveningness Questionnaire（Chinese version）, and National Institute of Health Stroke Scale. The relationship of nocturnal concentrations of melatonin, GABA and total antioxidants with insomnia after stroke was analyzed and showed that they were lower in the insomnia group than in the non-insomnia group. The severity of stroke was higher in the insomnia group than in the non-insomnia group. Correlation analysis demonstrated that the nocturnal concentrations of melatonin and GABA were associated with insomnia after stroke. This trial was registered at Clinical Trials.gov, identifier： NCT03202121.
文摘Fire numbers, burned areas and return intervals in each large scale forest type with average patch area of 500?km 2 in Heilongjiang Province during the period of 1980 to 1999 were obtained by overlapping the ignition points and areas of 1482 forest fires with the Province’s forest type maps in the same period by means of GIS software ARC/INFO. Analysis on the data indicated that the effects of the forest types on fire occurrence and burned areas in the Province were not significant, thus it was not necessary to take forest types into consideration when forest fire hazard was rated on a large scale. Years long human fire suppression activities increased fire return intervals in the region. Comparison was also made on the effects of forest types on fires at various scales.
