目的探讨全民加碘10年后浙江省8-10岁儿童的甲状腺容积的正常值及其校正方法,建立浙江省8-10岁儿童甲状腺容积的正常值标准。方法以2005年全国第5次碘缺乏病监测中的浙江省1110名8-10岁儿童B超测得的甲状腺容积数据为基础,应用SPSS10.0 ...目的探讨全民加碘10年后浙江省8-10岁儿童的甲状腺容积的正常值及其校正方法,建立浙江省8-10岁儿童甲状腺容积的正常值标准。方法以2005年全国第5次碘缺乏病监测中的浙江省1110名8-10岁儿童B超测得的甲状腺容积数据为基础,应用SPSS10.0 for windows统计软件进行统计分析检验。结果儿童甲状腺容积随着年龄的增加而递增,性别对甲状腺容积没有影响。浙江省8-10岁儿童甲状腺容积的正常值标准按年龄分组分别为:4.7、5.3和6.0ml。体质指数校正法(BMIV)、体重身高甲状腺容积指数法(WHVI)、体表面积甲状腺容积指数法(BSAV)和身高甲状腺容积指数法(HVI)四种甲状腺容积校正方法中,HVI校正法比其它校正方法更方便实用。结论浙江省8-10岁儿童甲状腺容积各年龄段的正常值标准较为合理,可为今后浙江省碘缺乏病监测及我国修订儿童甲状腺容积正常值标准提供依据。HVI是目前校正甲状腺容积的最适合方法。展开更多
AIM: To assess the prevalence and socio-demographic distribution of hepatitis B virus (HBV) infection in Albania. METHODS: Blood samples from 410 unselected schoolboys, 666 students, 500 military personnel, 1286 c...AIM: To assess the prevalence and socio-demographic distribution of hepatitis B virus (HBV) infection in Albania. METHODS: Blood samples from 410 unselected schoolboys, 666 students, 500 military personnel, 1286 casual blood donors, 378 voluntary blood donors and 640 pregnant women (total 3880 non-vaccinated residents of rural and metropolitan areas from all over Albania; 2354 (60.7%) male and 1526 (39.3%) female; mean age of 26.3 years) were tested during 2004-2006 for hepatitis B surface antigen (HBsAg) and antibodies to hepatitis B virus (anti-HBs) by ELISA. RESULTS: The HBsAg and anti-HBs prevalence were 9.5% and 28.7%, respectively. The highest HI3sAg prevalence was evident in the younger age group, such as in schoolchildren (11.8%) and the military (10.6%). Consequently, the anti-HBs prevalence increased with age, from 21.2% in schoolchildren (mean age: 15.7 years), to 36.3% in pregnant women (mean age: 26.3 years) and 29.7% in voluntary blood donors (mean age: 40.1 years). There were no significant differences between males and females. CONCLUSION: Despite the estimated two-fold reduction of HBsAg prevalence in the general population from about 18%-19% to 9.5%, Albania remains a highly endemic country (i.e. over 8% of HBsAg prevalence rate).展开更多
AIM:To characterize peripheral refraction and its relationship with myopia development in a selected group of male teenage Chinese students.METHODS:This 2-year prospective cohort study randomly enrolled 85 non-myopic ...AIM:To characterize peripheral refraction and its relationship with myopia development in a selected group of male teenage Chinese students.METHODS:This 2-year prospective cohort study randomly enrolled 85 non-myopic boys(age,14-16 y)from the Experimental Class of Air Force in China.Cycloplegic peripheral refraction was examined at 0°,±10°,and±20°along the horizontal visual field in the right eye at the baseline and 2-year follow-up.RESULTS:The incidence of myopia at the 2-year followup was 15.29%(13/85).The baseline central refraction(CR)and peripheral refraction at±10°were significantly lower in students who developed myopia than in those who did not(P<0.05).Relative peripheral refraction(RPR)did not differ between students with and without myopia(P>0.05).At the 2-year follow-up,the RPR at±10°and 20°nasal was significantly more hyperopic in the myopic group than in the non-myopic group.Multiple linear regression analysis indicated that the change in CR was significantly correlated with the changes in RPR at 20°nasal,10°nasal,and 20°temporal.Multivariate Logistic regression analysis indicated that the baseline CR[odds ratio(OR):0.092,95%confidence interval(CI):0.012-0.688,P=0.020]and the baseline RPR at 10°nasal(OR:0.182,95%CI:0.042-0.799,P=0.024)were significantly correlated with incident myopia(Omnibus test,χ=10.20,P=0.006).CONCLUSION:CR change is significantly correlated with changes in RPR,and students who develop myopia have more relative peripheral hyperopia.More baseline CR and relative peripheral hyperopia at 10°nasal are protective of myopia onset.展开更多
文摘目的探讨全民加碘10年后浙江省8-10岁儿童的甲状腺容积的正常值及其校正方法,建立浙江省8-10岁儿童甲状腺容积的正常值标准。方法以2005年全国第5次碘缺乏病监测中的浙江省1110名8-10岁儿童B超测得的甲状腺容积数据为基础,应用SPSS10.0 for windows统计软件进行统计分析检验。结果儿童甲状腺容积随着年龄的增加而递增,性别对甲状腺容积没有影响。浙江省8-10岁儿童甲状腺容积的正常值标准按年龄分组分别为:4.7、5.3和6.0ml。体质指数校正法(BMIV)、体重身高甲状腺容积指数法(WHVI)、体表面积甲状腺容积指数法(BSAV)和身高甲状腺容积指数法(HVI)四种甲状腺容积校正方法中,HVI校正法比其它校正方法更方便实用。结论浙江省8-10岁儿童甲状腺容积各年龄段的正常值标准较为合理,可为今后浙江省碘缺乏病监测及我国修订儿童甲状腺容积正常值标准提供依据。HVI是目前校正甲状腺容积的最适合方法。
文摘AIM: To assess the prevalence and socio-demographic distribution of hepatitis B virus (HBV) infection in Albania. METHODS: Blood samples from 410 unselected schoolboys, 666 students, 500 military personnel, 1286 casual blood donors, 378 voluntary blood donors and 640 pregnant women (total 3880 non-vaccinated residents of rural and metropolitan areas from all over Albania; 2354 (60.7%) male and 1526 (39.3%) female; mean age of 26.3 years) were tested during 2004-2006 for hepatitis B surface antigen (HBsAg) and antibodies to hepatitis B virus (anti-HBs) by ELISA. RESULTS: The HBsAg and anti-HBs prevalence were 9.5% and 28.7%, respectively. The highest HI3sAg prevalence was evident in the younger age group, such as in schoolchildren (11.8%) and the military (10.6%). Consequently, the anti-HBs prevalence increased with age, from 21.2% in schoolchildren (mean age: 15.7 years), to 36.3% in pregnant women (mean age: 26.3 years) and 29.7% in voluntary blood donors (mean age: 40.1 years). There were no significant differences between males and females. CONCLUSION: Despite the estimated two-fold reduction of HBsAg prevalence in the general population from about 18%-19% to 9.5%, Albania remains a highly endemic country (i.e. over 8% of HBsAg prevalence rate).
基金Supported by National Natural Science Foundation of China(No.81800854)Joint Innovation Project of National Defense Technology Innovation Zone(No.20-163-15-ZT-001-001-10)Efficiency Improvement Project of Air Force Medical University(No.2021HKYX24)。
文摘AIM:To characterize peripheral refraction and its relationship with myopia development in a selected group of male teenage Chinese students.METHODS:This 2-year prospective cohort study randomly enrolled 85 non-myopic boys(age,14-16 y)from the Experimental Class of Air Force in China.Cycloplegic peripheral refraction was examined at 0°,±10°,and±20°along the horizontal visual field in the right eye at the baseline and 2-year follow-up.RESULTS:The incidence of myopia at the 2-year followup was 15.29%(13/85).The baseline central refraction(CR)and peripheral refraction at±10°were significantly lower in students who developed myopia than in those who did not(P<0.05).Relative peripheral refraction(RPR)did not differ between students with and without myopia(P>0.05).At the 2-year follow-up,the RPR at±10°and 20°nasal was significantly more hyperopic in the myopic group than in the non-myopic group.Multiple linear regression analysis indicated that the change in CR was significantly correlated with the changes in RPR at 20°nasal,10°nasal,and 20°temporal.Multivariate Logistic regression analysis indicated that the baseline CR[odds ratio(OR):0.092,95%confidence interval(CI):0.012-0.688,P=0.020]and the baseline RPR at 10°nasal(OR:0.182,95%CI:0.042-0.799,P=0.024)were significantly correlated with incident myopia(Omnibus test,χ=10.20,P=0.006).CONCLUSION:CR change is significantly correlated with changes in RPR,and students who develop myopia have more relative peripheral hyperopia.More baseline CR and relative peripheral hyperopia at 10°nasal are protective of myopia onset.