CdSe:Sm nanocrystals(NCs) were synthesized by a water phase method,and their structures,shapes and optical properties were further characterized.X-ray diffraction(XRD) analysis suggested that both the CdSe and CdSe:Sm...CdSe:Sm nanocrystals(NCs) were synthesized by a water phase method,and their structures,shapes and optical properties were further characterized.X-ray diffraction(XRD) analysis suggested that both the CdSe and CdSe:Sm NCs contained(111),(220) and(311) lattice planes in the zinc blende structure overlapped with the(002),(110) and(112) lattice planes in the wurtzite structure,and the diameters were about 4.2,3.3 and 2.3 nm for CdSe,CdSe:Sm(8%) and CdSe:Sm(10%) NCs,respectively.All of the CdSe:Sm NCs were monodispersed and uniform spherical nanocrystals.The CdSe:Sm(10%) NCs prepared with different reaction times exhibited constant absorption spectra at 430 nm and a fixed emission peak at581 nm.Compared with those of pure CdSe NCs,the fluorescence emission of CdSe:Sm(10%) NCs blueshifted 20-36 nm,and the absorption peak initially redshifted and then blueshifted with the prolongation of reaction time.In addition,the Sm^2+ doping decreased the fluorescence lifetime and increased the quantum yields(QYs) of CdSe NCs.The QYs of CdSe:Sm NCs increased initially and then decreased with the increase in the amount of doped Sm2+.The initial pH and charge compensator concentration also exhibited significantly enhanced fluorescence emission of CdSe:Sm NCs.展开更多
As an anticonvulsant,the influences of Qingyangshen(QYS)on the development of brainand memory behavior were observed in four-week-old male rats.The dosage of QYS was100 mg/kg/QOD and the period of administration was o...As an anticonvulsant,the influences of Qingyangshen(QYS)on the development of brainand memory behavior were observed in four-week-old male rats.The dosage of QYS was100 mg/kg/QOD and the period of administration was one month.The results showedthat QYS had less influence on the development of body weight and brain wet weight inyoung-aged rats than diphenylhydantoin(DPH).However,QYS inhibited the establish-ment of passive avoidance conditional reflex and had influence on memory behavior inyoung-aged rats.展开更多
The concentrations of central neuropeptides,somatostatin(SS) and substance-P (SP),were determined in the different brain regions of young-aged male rats after a long-term ad-m inistration of anticonvulsants Qingyangsh...The concentrations of central neuropeptides,somatostatin(SS) and substance-P (SP),were determined in the different brain regions of young-aged male rats after a long-term ad-m inistration of anticonvulsants Qingyangshen(QYS),Diphenylhydantoin(DPH),andCarbamazepine(CBZ).The results were compared with Pentylenetetrazol(PTZ)-inducedseizure model and normal saline-treated controls.No effects of QYS on the concentrationsof SS and SP were found in the rats of four-week or eight week groups.Both of DPH andPTZ increased the SS levels in the midbrain of rats in four-week gronp.DPH,CBZ,andPTZ also increased the SP levels in the cerebral cortex,striatum,and brain stem of rats ineight-week group.Our present data indicated that the central neuropeptides SS and SPwere involved in the processes of epilepsy and antiepilepsy.Since QYS did not influence thecontents of SS and SP after a long-term administration,it suggested that theanticonvulsant mechanism of QYS may be different from those of DPH and CBZ,i.e.itmay be not due to its effect on the central neuropeptide pathway.展开更多
The effects of QYS on the functions of central GABAergic system in mice brain were investi-gated by determining the release and uptake of label GABA and Glu in the brain slice andextractive synaptic membrane.The drama...The effects of QYS on the functions of central GABAergic system in mice brain were investi-gated by determining the release and uptake of label GABA and Glu in the brain slice andextractive synaptic membrane.The dramatic actions of QYS in the oral group were showed bythe increasing releases of ~3H-GABA and ~3H-Glu after high K^+ stimulation in the anterior partof hemispheres slices.However,the GAD activity in the hippocampus slice of QYS-treatedgroup was not influenced as the PTZ-treated group.No effect of QYS on the uptakes of^3H-GABA and ~3H-Glu in the extractive synaptic membrane was found in the intraperitonealgroup.These results suggested that QYS does influence the functions of central GABAergic sys-tern due to the increasing releases of GABA and Glu in the anterior part of hemispheres,whichmay play an important role in the anticonvulsant action of QYS.展开更多
Novel rare-earth (RE;e.g., europium (Eu^(3+)), samarium (Sm^(3+)), and praseodymium (Pr^(3+))) and transition metal (TM^(4+);e.g., manganese (Mn^(4+))) ion single-/co-doped double-perovskite Ca2InTaO6 (CITO) phosphors...Novel rare-earth (RE;e.g., europium (Eu^(3+)), samarium (Sm^(3+)), and praseodymium (Pr^(3+))) and transition metal (TM^(4+);e.g., manganese (Mn^(4+))) ion single-/co-doped double-perovskite Ca2InTaO6 (CITO) phosphors were prepared and investigated with respect to their crystal structure and photoluminescence (PL) properties. Among them, the CITO:Eu^(3+) phosphors were found to exhibit an ultra-high internal PL quantum yield (89.1%) and good thermal stability (78.7% at 423 K relative to the initial value at 303 K). As such, the corresponding packaged white light-emitting diode (LED) was able to display a remarkable color rendering index (CRI;= 91.51@10 mA). Besides, the potential in applications of anti-counterfeiting fields and a novel LED structure based on flexible phosphor-converted films was also studied. Moreover, due to their different thermal quenching, trivalent lanthanide (Ln^(3+))/Mn^(4+) co-doped CITO phosphors were designed for optical thermometry based on the luminescence intensity ratio (LIR) between different 4f transitions of various Ln^(3+) ions and ^(2)Eg → ^(4)A_(2g) (Mn^(4+)) transition. Particularly, the LIR between the ^(4)G_(5/2) → ^(6)H_(9/2) and ^(2)Eg → ^(4)A_(2g) peaks of the CITO activated with 5 mol% Sm^(3+) and 0.3 mol% Mn^(4+) exhibited the most excellent relative sensitivity (Sr;= 3.80 %·K^(−1)) with beneficial temperature uncertainty of 0.0648 K. Overall, these results are of significance to offer valuable databases for constructing multifunctional high-performance optical platforms using single-/co-doped double-perovskite tantalates.展开更多
基金financially supported by the National Natural Science Foundation of China(No.21364007)the Natural Science Foundation of Inner Mongolia(No.2016MS0201)the Program for Young Talents of Science and Technology of Baotou Teachers College(No.01135003/003)
文摘CdSe:Sm nanocrystals(NCs) were synthesized by a water phase method,and their structures,shapes and optical properties were further characterized.X-ray diffraction(XRD) analysis suggested that both the CdSe and CdSe:Sm NCs contained(111),(220) and(311) lattice planes in the zinc blende structure overlapped with the(002),(110) and(112) lattice planes in the wurtzite structure,and the diameters were about 4.2,3.3 and 2.3 nm for CdSe,CdSe:Sm(8%) and CdSe:Sm(10%) NCs,respectively.All of the CdSe:Sm NCs were monodispersed and uniform spherical nanocrystals.The CdSe:Sm(10%) NCs prepared with different reaction times exhibited constant absorption spectra at 430 nm and a fixed emission peak at581 nm.Compared with those of pure CdSe NCs,the fluorescence emission of CdSe:Sm(10%) NCs blueshifted 20-36 nm,and the absorption peak initially redshifted and then blueshifted with the prolongation of reaction time.In addition,the Sm^2+ doping decreased the fluorescence lifetime and increased the quantum yields(QYs) of CdSe NCs.The QYs of CdSe:Sm NCs increased initially and then decreased with the increase in the amount of doped Sm2+.The initial pH and charge compensator concentration also exhibited significantly enhanced fluorescence emission of CdSe:Sm NCs.
文摘As an anticonvulsant,the influences of Qingyangshen(QYS)on the development of brainand memory behavior were observed in four-week-old male rats.The dosage of QYS was100 mg/kg/QOD and the period of administration was one month.The results showedthat QYS had less influence on the development of body weight and brain wet weight inyoung-aged rats than diphenylhydantoin(DPH).However,QYS inhibited the establish-ment of passive avoidance conditional reflex and had influence on memory behavior inyoung-aged rats.
文摘The concentrations of central neuropeptides,somatostatin(SS) and substance-P (SP),were determined in the different brain regions of young-aged male rats after a long-term ad-m inistration of anticonvulsants Qingyangshen(QYS),Diphenylhydantoin(DPH),andCarbamazepine(CBZ).The results were compared with Pentylenetetrazol(PTZ)-inducedseizure model and normal saline-treated controls.No effects of QYS on the concentrationsof SS and SP were found in the rats of four-week or eight week groups.Both of DPH andPTZ increased the SS levels in the midbrain of rats in four-week gronp.DPH,CBZ,andPTZ also increased the SP levels in the cerebral cortex,striatum,and brain stem of rats ineight-week group.Our present data indicated that the central neuropeptides SS and SPwere involved in the processes of epilepsy and antiepilepsy.Since QYS did not influence thecontents of SS and SP after a long-term administration,it suggested that theanticonvulsant mechanism of QYS may be different from those of DPH and CBZ,i.e.itmay be not due to its effect on the central neuropeptide pathway.
文摘The effects of QYS on the functions of central GABAergic system in mice brain were investi-gated by determining the release and uptake of label GABA and Glu in the brain slice andextractive synaptic membrane.The dramatic actions of QYS in the oral group were showed bythe increasing releases of ~3H-GABA and ~3H-Glu after high K^+ stimulation in the anterior partof hemispheres slices.However,the GAD activity in the hippocampus slice of QYS-treatedgroup was not influenced as the PTZ-treated group.No effect of QYS on the uptakes of^3H-GABA and ~3H-Glu in the extractive synaptic membrane was found in the intraperitonealgroup.These results suggested that QYS does influence the functions of central GABAergic sys-tern due to the increasing releases of GABA and Glu in the anterior part of hemispheres,whichmay play an important role in the anticonvulsant action of QYS.
基金supported by the National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIP)(No.2018R1A6A1A03025708).
文摘Novel rare-earth (RE;e.g., europium (Eu^(3+)), samarium (Sm^(3+)), and praseodymium (Pr^(3+))) and transition metal (TM^(4+);e.g., manganese (Mn^(4+))) ion single-/co-doped double-perovskite Ca2InTaO6 (CITO) phosphors were prepared and investigated with respect to their crystal structure and photoluminescence (PL) properties. Among them, the CITO:Eu^(3+) phosphors were found to exhibit an ultra-high internal PL quantum yield (89.1%) and good thermal stability (78.7% at 423 K relative to the initial value at 303 K). As such, the corresponding packaged white light-emitting diode (LED) was able to display a remarkable color rendering index (CRI;= 91.51@10 mA). Besides, the potential in applications of anti-counterfeiting fields and a novel LED structure based on flexible phosphor-converted films was also studied. Moreover, due to their different thermal quenching, trivalent lanthanide (Ln^(3+))/Mn^(4+) co-doped CITO phosphors were designed for optical thermometry based on the luminescence intensity ratio (LIR) between different 4f transitions of various Ln^(3+) ions and ^(2)Eg → ^(4)A_(2g) (Mn^(4+)) transition. Particularly, the LIR between the ^(4)G_(5/2) → ^(6)H_(9/2) and ^(2)Eg → ^(4)A_(2g) peaks of the CITO activated with 5 mol% Sm^(3+) and 0.3 mol% Mn^(4+) exhibited the most excellent relative sensitivity (Sr;= 3.80 %·K^(−1)) with beneficial temperature uncertainty of 0.0648 K. Overall, these results are of significance to offer valuable databases for constructing multifunctional high-performance optical platforms using single-/co-doped double-perovskite tantalates.
