Objective:To study the relationship between sleep disturbances and symptoms in patients with Parkinson’s disease(PD).Methods:The Parkinson’s Disease Sleep Scale-Chinese Version(PDSS-CV)was used to evaluate the sleep...Objective:To study the relationship between sleep disturbances and symptoms in patients with Parkinson’s disease(PD).Methods:The Parkinson’s Disease Sleep Scale-Chinese Version(PDSS-CV)was used to evaluate the sleep disturbances of PD patients in a cross sectional study.The Unified Parkinson’s Disease Rating Scale(UPDRS)parts II-IV,and the Hoehn&Yahr(H&Y)stage were used to determine the level of motor function in PD and the severity of PD.The Spearman correlation and a multiple regression analysis were used to identify the relationship between sleep disturbances and symptoms of PD.The quantities derived from the UPDRS and the H&Y stage and disease duration were compared between groups of patients either with or without sleep disturbances identified by the PDSS.This study was conducted from December 2011 to March 2012 at the First Affiliated Hospital of Sun Yat-sen University,in Guangzhou.Results:A total of 136 PD patients were included in this study.The overall total PDSS score in PD patients was 107.58±23.35 points(range:30–146).There were significant differences in the disease duration,the H&Y stage,and the UPDRS section subscores between groups of patients either with or without sleep disturbances(Kruskal-Wallis Test,p<0.05).There were significant negative correlations between PDSS scores and the UPDRS subscores,the H&Y stage and the disease duration(Spearman correlation,p<0.05).The multiple regression analysis indicated that sleep disturbances identified by the PDSS were only associated with daily life activity,tremor intensity and clinical fluctuation(R2=0.22,F(3,132)=12.4,p<0.001).The correlations were also significant when the contribution of the other two factors was excluded using partial correlations.Conclusions:The level of daily life activity and the occurrences of tremor and clinical fluctuation are likely to be important factors that lead to PD patients’sleep disturbances.This study may elucidate an important clue for the relationship between sleep disturbances and PD symptoms.展开更多
目的探讨抗阻力运动护理应用于老年帕金森睡眠障碍患者的效果。方法根据随机数字表法将2020年3月-2021年6月到恩施州优抚医院接受治疗的86例老年帕金森睡眠障碍患者分为对照组43例与观察组43例。两组患者入院均接受基础的临床治疗,对照...目的探讨抗阻力运动护理应用于老年帕金森睡眠障碍患者的效果。方法根据随机数字表法将2020年3月-2021年6月到恩施州优抚医院接受治疗的86例老年帕金森睡眠障碍患者分为对照组43例与观察组43例。两组患者入院均接受基础的临床治疗,对照组采用常规的临床护理,观察组在对照组的基础上采用抗阻力运动护理。连续治疗3个月后,比较两组患者的治疗效果、睡眠质量、精神状况以及生活质量。结果治疗3个月后观察组总有效率高于对照组(P<0.05);两组匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI)入睡时间、睡眠时间、睡眠障碍、睡眠效率、主观睡眠时间、日间功能障碍、催眠药物应用及总分均低于治疗前,且观察组明显低于对照组(P<0.05);两组汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)评分均低于治疗前,且观察组明显低于对照组(P<0.05);两组简易精神状况检查量表(Minimental state examination,MMSE)、生活质量综合评分问卷(Generic Quality of Life Inventory,GQOLI)评分均明显高于治疗前,且观察组明显高于对照组(P<0.05)。结论抗阻力运动护理应用于老年帕金森睡眠障碍患者效果显著,可明显改善患者睡眠质量以及精神状况,提高预后生活质量。展开更多
基金This study was supported by grants from the Guangdong Natural Science Foundation(No.10151008901000187)the Guangdong Science and Technology Foundation(No.2010B080701107).
文摘Objective:To study the relationship between sleep disturbances and symptoms in patients with Parkinson’s disease(PD).Methods:The Parkinson’s Disease Sleep Scale-Chinese Version(PDSS-CV)was used to evaluate the sleep disturbances of PD patients in a cross sectional study.The Unified Parkinson’s Disease Rating Scale(UPDRS)parts II-IV,and the Hoehn&Yahr(H&Y)stage were used to determine the level of motor function in PD and the severity of PD.The Spearman correlation and a multiple regression analysis were used to identify the relationship between sleep disturbances and symptoms of PD.The quantities derived from the UPDRS and the H&Y stage and disease duration were compared between groups of patients either with or without sleep disturbances identified by the PDSS.This study was conducted from December 2011 to March 2012 at the First Affiliated Hospital of Sun Yat-sen University,in Guangzhou.Results:A total of 136 PD patients were included in this study.The overall total PDSS score in PD patients was 107.58±23.35 points(range:30–146).There were significant differences in the disease duration,the H&Y stage,and the UPDRS section subscores between groups of patients either with or without sleep disturbances(Kruskal-Wallis Test,p<0.05).There were significant negative correlations between PDSS scores and the UPDRS subscores,the H&Y stage and the disease duration(Spearman correlation,p<0.05).The multiple regression analysis indicated that sleep disturbances identified by the PDSS were only associated with daily life activity,tremor intensity and clinical fluctuation(R2=0.22,F(3,132)=12.4,p<0.001).The correlations were also significant when the contribution of the other two factors was excluded using partial correlations.Conclusions:The level of daily life activity and the occurrences of tremor and clinical fluctuation are likely to be important factors that lead to PD patients’sleep disturbances.This study may elucidate an important clue for the relationship between sleep disturbances and PD symptoms.
文摘目的探讨抗阻力运动护理应用于老年帕金森睡眠障碍患者的效果。方法根据随机数字表法将2020年3月-2021年6月到恩施州优抚医院接受治疗的86例老年帕金森睡眠障碍患者分为对照组43例与观察组43例。两组患者入院均接受基础的临床治疗,对照组采用常规的临床护理,观察组在对照组的基础上采用抗阻力运动护理。连续治疗3个月后,比较两组患者的治疗效果、睡眠质量、精神状况以及生活质量。结果治疗3个月后观察组总有效率高于对照组(P<0.05);两组匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI)入睡时间、睡眠时间、睡眠障碍、睡眠效率、主观睡眠时间、日间功能障碍、催眠药物应用及总分均低于治疗前,且观察组明显低于对照组(P<0.05);两组汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)评分均低于治疗前,且观察组明显低于对照组(P<0.05);两组简易精神状况检查量表(Minimental state examination,MMSE)、生活质量综合评分问卷(Generic Quality of Life Inventory,GQOLI)评分均明显高于治疗前,且观察组明显高于对照组(P<0.05)。结论抗阻力运动护理应用于老年帕金森睡眠障碍患者效果显著,可明显改善患者睡眠质量以及精神状况,提高预后生活质量。
