Objective:To explore the expression and significance of human epidermal growth factor(EOF) and nerve growth factor(NGF) in patients with knee osteoarthritis. Methods:RT-PCR and enzyme-linked immunosorbent assay were u...Objective:To explore the expression and significance of human epidermal growth factor(EOF) and nerve growth factor(NGF) in patients with knee osteoarthritis. Methods:RT-PCR and enzyme-linked immunosorbent assay were used to measure the serum EOF and NGF expression levels of patients with limb fracture and brain trauma injurry after 1 d,3 d,7 d,14 d and the relationship between them was analyzed.The level was compared among the simple fracture group,traumatic brain injury group and the normal control group,with 40 cases in each group.Results:The serum NGF levels were significantly different among three groups. Senun NGF,EGF mKNA and protein levels gradually decreased with the increasing injury time in the limb fracture combined with brain injury gnmp,traumatic brain injury group,the simple fracture group and the health control group(P【0.05).Conclusions:The serum of NGF.EGF levels significandy increased when limb fracture combined with brain injury,so EGF and NGF may be involved in the process of fracture healing.展开更多
This study examines the impact of electric solar wind sail(E-sail)parameters on the attitude stability of E-sail’s central spacecraft by using a comprehensive rigid–flexible coupling dynamic model.In this model,the ...This study examines the impact of electric solar wind sail(E-sail)parameters on the attitude stability of E-sail’s central spacecraft by using a comprehensive rigid–flexible coupling dynamic model.In this model,the nodal position finite element method is used to model the elastic deformation of the tethers through interconnected two-node tensile elements.The attitude dynamics of the central spacecraft is described using a natural coordinate formulation.The rigid–flexible coupling between the central spacecraft and its flexible tethers is established using Lagrange multipliers.Our research reveals the significant influences of parameters such as tether numbers,tether’s electric potential,and solar wind velocity on attitude stability.Specifically,solar wind fluctuations and the distribution of electric potential on the main tethers considerably affect the attitude stability of the spacecraft.For consistent management,the angular velocities of the spacecraft must remain at target values.Moreover,the attitude stability of a spacecraft has a pronounced dependence on the geometrical configuration of the E-sail,with axisymmetric E-sails proving to be more stable.展开更多
Fabrication method and device of ultra-small gradient-index (GRIN) fiber probe were investigated in order to explore the development of ultra-small probes for optical coherence tomography (OCT) imaging. The beam- ...Fabrication method and device of ultra-small gradient-index (GRIN) fiber probe were investigated in order to explore the development of ultra-small probes for optical coherence tomography (OCT) imaging. The beam- expanding effect of no-core fiber (NCF) and the focusing properties of the GRIN fiber lens were analyzed based on the model of GRIN fiber probe consisting of single-mode fiber (SMF), NCF and GRIN fiber lens. A stereo micro- scope based system was developed to fabricate the GRIN fiber probe. A fiber fusion splicer and an ultrasonic cleaver were used to weld and cut the fiber respectively. A con- focal microscopy was used to measure the dimensions of probe components. The results show that the sizes of probe components developed are at the level of millimeter. Therefore, the proposed experimental system meets the fabrication requirements of an ultra-small self-focusing GRIN fiber probe. This shows that this fabrication device and method can be employed in the fabrication of ultra- small self-focusing GRIN fiber probe and applied in the study of miniaturized optical probes and OCT systems.展开更多
文摘Objective:To explore the expression and significance of human epidermal growth factor(EOF) and nerve growth factor(NGF) in patients with knee osteoarthritis. Methods:RT-PCR and enzyme-linked immunosorbent assay were used to measure the serum EOF and NGF expression levels of patients with limb fracture and brain trauma injurry after 1 d,3 d,7 d,14 d and the relationship between them was analyzed.The level was compared among the simple fracture group,traumatic brain injury group and the normal control group,with 40 cases in each group.Results:The serum NGF levels were significantly different among three groups. Senun NGF,EGF mKNA and protein levels gradually decreased with the increasing injury time in the limb fracture combined with brain injury gnmp,traumatic brain injury group,the simple fracture group and the health control group(P【0.05).Conclusions:The serum of NGF.EGF levels significandy increased when limb fracture combined with brain injury,so EGF and NGF may be involved in the process of fracture healing.
基金supported by the Fundamental Research Funds for the Central Universities(Grant No.XJSJ23128)Discovery Grant(Grant No.RGPIN2018-05991)from the Natural Sciences and Engineering Research Council of Canada.
文摘This study examines the impact of electric solar wind sail(E-sail)parameters on the attitude stability of E-sail’s central spacecraft by using a comprehensive rigid–flexible coupling dynamic model.In this model,the nodal position finite element method is used to model the elastic deformation of the tethers through interconnected two-node tensile elements.The attitude dynamics of the central spacecraft is described using a natural coordinate formulation.The rigid–flexible coupling between the central spacecraft and its flexible tethers is established using Lagrange multipliers.Our research reveals the significant influences of parameters such as tether numbers,tether’s electric potential,and solar wind velocity on attitude stability.Specifically,solar wind fluctuations and the distribution of electric potential on the main tethers considerably affect the attitude stability of the spacecraft.For consistent management,the angular velocities of the spacecraft must remain at target values.Moreover,the attitude stability of a spacecraft has a pronounced dependence on the geometrical configuration of the E-sail,with axisymmetric E-sails proving to be more stable.
基金supported by the National Natural Science Foundation of China(Grant No.41104065)the Dawn Planning Foundation of Shanghai Municipal Education Commission (Grant No.12CG047)by the Scientific Research Innovation Project of Shanghai Municipal Education Commission(Grant No. 13YZ022)
文摘Fabrication method and device of ultra-small gradient-index (GRIN) fiber probe were investigated in order to explore the development of ultra-small probes for optical coherence tomography (OCT) imaging. The beam- expanding effect of no-core fiber (NCF) and the focusing properties of the GRIN fiber lens were analyzed based on the model of GRIN fiber probe consisting of single-mode fiber (SMF), NCF and GRIN fiber lens. A stereo micro- scope based system was developed to fabricate the GRIN fiber probe. A fiber fusion splicer and an ultrasonic cleaver were used to weld and cut the fiber respectively. A con- focal microscopy was used to measure the dimensions of probe components. The results show that the sizes of probe components developed are at the level of millimeter. Therefore, the proposed experimental system meets the fabrication requirements of an ultra-small self-focusing GRIN fiber probe. This shows that this fabrication device and method can be employed in the fabrication of ultra- small self-focusing GRIN fiber probe and applied in the study of miniaturized optical probes and OCT systems.