The clinical effects of dosage during the period of treatment of Lithospermum Ruderale extract-a kind of Chinese traditional herbal medicine-on medicinal abortion induced by mifepristone and misoprostol were studied. ...The clinical effects of dosage during the period of treatment of Lithospermum Ruderale extract-a kind of Chinese traditional herbal medicine-on medicinal abortion induced by mifepristone and misoprostol were studied. Lithospermum Ruderale extract was administrated 3 d before, 3 d after or 3 d before plus 3 d after the administration of misoprostol respectively. The dose of Lithospermum Ruderale extract was 50 g, 75 g or 100 g respectively. Thus 1 350 women of early pregnancy were grouped into 9 groups and observed. The results showed that the effects of Lithospermum Ruderale used 3 d before, and 3 d before plus 3 d after (6 days misoprostol were significantly better than those only used 3 d after misoprostol both for complete abortion and bleeding (P<0.05). The dosage between 50 g and 100 g made no significant difference in clinical effects. Therefore it is reasonable to use 50 g Lithospermum Ruderale before misoprostol to improve medicinal abortion.展开更多
Objectives:To observe trophoblastic and other blood flows after medicinal abortion, to analyze factors of prolonged bleeding, and to determine indications for medicinal termination of early pregnancy. Methods:Transvag...Objectives:To observe trophoblastic and other blood flows after medicinal abortion, to analyze factors of prolonged bleeding, and to determine indications for medicinal termination of early pregnancy. Methods:Transvaginal color Doppler (TVCD) observation in combination with β--hCG determination in clinical trial involving 145 early pregnant women. Results: In cases of prolonged bleeding trophoblastic blood flow (TBF) is more significant. After aspiration of retained tissues, parallel to disappearance of TBF, prolonged uterine bleeding is stopped. Ectopics, lower--situated myoma and scar--site--implantation are relatively contraindicative for medicinal abortion. Too early pregnancy with too small embryonic--sac is not favourable. The sac is more difficult to be expelled. Prolonged bleeding can occur in cases of amenorrhea or recovery of menstruation due to retention of decidual tissues with microvilli. Conclusion: Retention of decidual tissues with microvilli plays an important role in the mechanism of prolonged uterine bleeding during medicinal termination of early pregnancy. TVCD is very helpful in monitoring this method. Ectopic pregnancy should be contraindicated. In cases of myoma or with history of cesarean section the location of implantation and myoma or scar should be examined by ultrasound before decision. Pregnancy of 6--7 weeks is more favorable for medicinal abortion.展开更多
目的:观察安宫黄体酮对药物流产后阴道出血的疗效。方法:将排除宫腔内滋养层细胞残留的98例药物流产后阴道出血者,随机分为观察组52例(安宫黄体酮12mg qd×7d治疗)和对照组46例(益母草颗粒剂20g b id×7d治疗)。结果:应用安宫...目的:观察安宫黄体酮对药物流产后阴道出血的疗效。方法:将排除宫腔内滋养层细胞残留的98例药物流产后阴道出血者,随机分为观察组52例(安宫黄体酮12mg qd×7d治疗)和对照组46例(益母草颗粒剂20g b id×7d治疗)。结果:应用安宫黄体酮后3d内阴道出血停止,撤退出血后B超示宫腔内1 cm以下的异常回声消失率达83.33%,与对照组比较差异有显著意义。结论:安宫黄体酮对除外宫腔残留的药物流产后阴道出血,止血迅速、有效。展开更多
基金This study was funded by National Family Planning Commission of China
文摘The clinical effects of dosage during the period of treatment of Lithospermum Ruderale extract-a kind of Chinese traditional herbal medicine-on medicinal abortion induced by mifepristone and misoprostol were studied. Lithospermum Ruderale extract was administrated 3 d before, 3 d after or 3 d before plus 3 d after the administration of misoprostol respectively. The dose of Lithospermum Ruderale extract was 50 g, 75 g or 100 g respectively. Thus 1 350 women of early pregnancy were grouped into 9 groups and observed. The results showed that the effects of Lithospermum Ruderale used 3 d before, and 3 d before plus 3 d after (6 days misoprostol were significantly better than those only used 3 d after misoprostol both for complete abortion and bleeding (P<0.05). The dosage between 50 g and 100 g made no significant difference in clinical effects. Therefore it is reasonable to use 50 g Lithospermum Ruderale before misoprostol to improve medicinal abortion.
文摘Objectives:To observe trophoblastic and other blood flows after medicinal abortion, to analyze factors of prolonged bleeding, and to determine indications for medicinal termination of early pregnancy. Methods:Transvaginal color Doppler (TVCD) observation in combination with β--hCG determination in clinical trial involving 145 early pregnant women. Results: In cases of prolonged bleeding trophoblastic blood flow (TBF) is more significant. After aspiration of retained tissues, parallel to disappearance of TBF, prolonged uterine bleeding is stopped. Ectopics, lower--situated myoma and scar--site--implantation are relatively contraindicative for medicinal abortion. Too early pregnancy with too small embryonic--sac is not favourable. The sac is more difficult to be expelled. Prolonged bleeding can occur in cases of amenorrhea or recovery of menstruation due to retention of decidual tissues with microvilli. Conclusion: Retention of decidual tissues with microvilli plays an important role in the mechanism of prolonged uterine bleeding during medicinal termination of early pregnancy. TVCD is very helpful in monitoring this method. Ectopic pregnancy should be contraindicated. In cases of myoma or with history of cesarean section the location of implantation and myoma or scar should be examined by ultrasound before decision. Pregnancy of 6--7 weeks is more favorable for medicinal abortion.
文摘目的:观察安宫黄体酮对药物流产后阴道出血的疗效。方法:将排除宫腔内滋养层细胞残留的98例药物流产后阴道出血者,随机分为观察组52例(安宫黄体酮12mg qd×7d治疗)和对照组46例(益母草颗粒剂20g b id×7d治疗)。结果:应用安宫黄体酮后3d内阴道出血停止,撤退出血后B超示宫腔内1 cm以下的异常回声消失率达83.33%,与对照组比较差异有显著意义。结论:安宫黄体酮对除外宫腔残留的药物流产后阴道出血,止血迅速、有效。
